-
公开(公告)号：EP1807182B1
公开(公告)日：2009-02-18
申请号：EP05777913.4
申请日：2005-09-04
CPC分类号： B01D67/0093 , B01D71/56 , B01D2323/38 , C02F1/441
摘要： The invention provides a process for improving the antifouling properties and for increasing the selectivity of commercial composite polyamide nanofiltration (NF) and reverse osmosis (RO) membranes comprising circulating a low concentration of water soluble monomers and an initiating redox couple in an aqueous solvent, without transverse pressure over the surface of the membrane thereby effecting a free-radical graft polymerization on the surface of the membrane.
-
2.发明公开NANO-SIZED PARTICLES COMPRISING MULTI-HEADED AMPHIPHILES FOR TARGETED DRUG DELIVERY 审中-公开NANOTEILCHEN MITMEHRKÖPFIGENAMPHIPHILEN ZUR GEZIELTEN ARZNEIABGABE
公开(公告)号：EP2427175A2
公开(公告)日：2012-03-14
申请号：EP10725503.6
申请日：2010-05-04
CPC分类号： A61K9/1272 , A61K9/0019 , A61K9/127 , A61K9/51 , C07C229/22
摘要： Nano-sized particles are provided comprising at least one multi-headed amphiphilic compound, in which at least one headgroup of said multi-headed amphiphilic compound is selectively cleavable or contains a selectively cleavable group, and at least one biologically active agent, which is both encapsulated within the nano-particle and non-covalently associated thereto.
摘要翻译： 提供包含至少一种多头两亲化合物的纳米尺寸颗粒，其中所述多头两亲化合物的至少一个头基可选择性切割或含有选择性可切割基团，以及至少一种生物活性剂，其均为 封装在纳米颗粒内并与其非共价缔合。
-
3.发明公开AMPHIPHILIC DERIVATIVES FOR THE PRODUCTION OF VESICLES, MICELLES AND COMPLEXANTS, AND PRECURSORS THEREOF 审中-公开“两亲衍生物用于制备囊泡，胶束和络合剂，它们的PRE”
公开(公告)号：EP1360168A2
公开(公告)日：2003-11-12
申请号：EP02716274.2
申请日：2002-01-16
IPC分类号： C07C69/76
CPC分类号： C07C247/12 , A61K8/14 , A61K8/41 , A61K8/416 , A61K8/42 , A61K8/46 , A61K8/4926 , A61K8/922 , A61K9/0014 , A61K9/1075 , A61K9/1272 , A61K47/18 , A61K47/24 , A61Q19/00 , C07C69/675 , C07C69/732 , C07C229/12 , C07C229/22 , C07C235/28 , C07C301/00 , C07D213/53 , C07D303/04 , C07D303/48 , C07D407/12 , C07F9/65505
摘要： Amphiphilic derivatives composed of at least one fatty acid chain are derived from natural vegetable oils such as vernonia oil, lesquerella oil and castor oil, in which the several reactive groups such as epoxy, hydroxy and double bonds can be modified to polar and ionic groups. The head group of the amphiphilic derivative may be in the main fatty acid chain or in a side chain. The amphiphiles are useful for the formation of vesicles and micelles and for use as complexants and surfactants.
-
公开(公告)号：EP2033324B1
公开(公告)日：2016-04-13
申请号：EP07736374.5
申请日：2007-05-24
发明人： LINDER, Charles , KEDEM, Ora , OREN, Yoram
IPC分类号： B01D67/00 , B01D69/10 , B01D69/12 , B01D71/28 , B01D71/32 , B01D71/68 , B01D71/82 , H01M8/10
CPC分类号： B01D67/0006 , B01D69/10 , B01D69/105 , B01D69/125 , B01D71/28 , B01D71/32 , B01D71/52 , B01D71/68 , B01D71/82 , B01D2323/30 , B01D2323/40 , H01M8/1023 , H01M8/1025 , H01M8/1027 , H01M8/1032 , H01M8/1039 , H01M8/1041 , H01M8/1072 , H01M8/1081 , H01M2300/0082 , Y02P70/56
-
公开(公告)号：EP2033324A2
公开(公告)日：2009-03-11
申请号：EP07736374.5
申请日：2007-05-24
发明人： LINDER, Charles , KEDEM, Ora , OREN, Yoram
IPC分类号： H04B1/16
CPC分类号： B01D67/0006 , B01D69/10 , B01D69/105 , B01D69/125 , B01D71/28 , B01D71/32 , B01D71/52 , B01D71/68 , B01D71/82 , B01D2323/30 , B01D2323/40 , H01M8/1023 , H01M8/1025 , H01M8/1027 , H01M8/1032 , H01M8/1039 , H01M8/1041 , H01M8/1072 , H01M8/1081 , H01M2300/0082 , Y02P70/56
摘要： There are provided herein selective membranes, such as composite membranes, and/or films and processes for their preparation. The membranes and/or films have a given morphology which may be stabilized, for example against swelling and chemical degradation, by covalent crosslinking and optionally, in addition, by hydrophobization. There is provided a membrane and/or film and a process for the preparation thereof, the membrane and/or film include an ionomer and/or polyelectrolyte crosslinked through aryl-aryl (-Ar-Ar-), aryl-ether-aryl (-Ar-O-Ar-) and/or aryl-sulfide-aryl (-Ar-S-Ar-) bonds.
-
公开(公告)号：EP1622713A1
公开(公告)日：2006-02-08
申请号：EP04731450.5
申请日：2004-05-06
发明人： MARKUS, Arie , LINDER, Charles
CPC分类号： A01N25/28 , A01N65/00 , A01N65/06 , A01N65/28 , B01J13/16 , Y02A50/351 , Y10T428/2984 , A01N2300/00
摘要： The invention provides a process for the preparation of essential oil microcapsules comprising dissolving a di- or polyisocyanate into an essential oil, emulsifying the resulting mixture in an aqueous solution containing a di- or polyamine, and or a di or polyhydroxy compound to effect encapsulation of said essential oil through interfacial polymerization, whereby there is formed a polyurea and/or polyurethane film around the essential oil droplets which film enhances the stability of said essential oil, reduces its evaporation rate and controls its release rate when applied to a substrate.
-
公开(公告)号：EP2427175B1
公开(公告)日：2018-08-29
申请号：EP10725503.6
申请日：2010-05-04
CPC分类号： A61K9/1272 , A61K9/0019 , A61K9/127 , A61K9/51 , C07C229/22
摘要： Nano-sized particles are provided comprising at least one multi-headed amphiphilic compound, in which at least one headgroup of said multi-headed amphiphilic compound is selectively cleavable or contains a selectively cleavable group, and at least one biologically active agent, which is both encapsulated within the nano-particle and non-covalently associated thereto.
-
8.发明公开CHEMICALLY RESISTANT MEMBRANES, COATINGS AND FILMS AND METHODS FOR THEIR PREPARATION 审中-公开耐化学腐蚀的膜材料涂层和薄膜及其制造方法
公开(公告)号：EP2398578A1
公开(公告)日：2011-12-28
申请号：EP10711723.6
申请日：2010-02-21
发明人： LINDER, Charles , KEDEM, Ora , OREN, Yoram
CPC分类号： C08G75/00 , B01D67/0006 , B01D69/125 , B01D71/52 , B01D71/66 , B01D71/68 , B01D71/82 , B01D2323/30 , B01D2323/36 , B01D2323/40 , B01D2325/28 , B01D2325/30 , C08G65/00
摘要： There is provided herein a membrane or film comprising one or more aromatic ionomers covalently crosslinked through aryl-aryl (-Ar-Ar-), aryl-ether-aryl (-Ar-O-Ar-), aryl-sulfide-aryl (-Ar-S-Ar-), aryl-sulfone-aryl bonds, or any combination thereof, wherein said one or more aromatic ionomers further comprises at least one electron withdrawing group adapted to improve oxidant resistance of said membrane or film.
-
公开(公告)号：EP1807182A1
公开(公告)日：2007-07-18
申请号：EP05777913.4
申请日：2005-09-04
CPC分类号： B01D67/0093 , B01D71/56 , B01D2323/38 , C02F1/441
摘要： The invention provides a process for improving the antifouling properties and for increasing the selectivity of commercial composite polyamide nanofiltration (NF) and reverse osmosis (RO) membranes comprising circulating a low concentration of water soluble monomers and an initiating redox couple in an aqueous solvent, without transverse pressure over the surface of the membrane thereby effecting a free-radical graft polymerization on the surface of the membrane.
-
10.发明公开AMPHIPHILIC COMPOUNDS AND VESICLES/LIPOSOMES FOR ORGAN-SPECIFIC DRUG TARGETING 审中-公开两亲化合物和囊泡/脂质体为该机构特异性药物靶向
公开(公告)号：EP1461014A2
公开(公告)日：2004-09-29
申请号：EP02788510.2
申请日：2002-12-04
IPC分类号： A61K9/127 , C07D303/00 , C07C233/00
CPC分类号： C07D401/04 , A61K9/1272 , C07C219/06 , C07C233/36 , C07C235/28 , C07C237/10 , C07D303/46 , C07H7/00 , C07H15/10 , C07H15/26
摘要： An amphiphilic compound is provided capable of forming vesicles or liposomes, said amphiphilic compound having at least one headgroup containing a selectively cleavable group or moiety such as a residue of a choline or phenylalanine derivative, and at least one hydrogen-bonding group located either within said headgroup and/or in close proximity thereto. The cleavable group or moiety is cleaved under selective conditions including change of chemical, physical or biological environment and is preferably cleaved enzymatically in a biological environment such as the brain or the blood. Vesicles or liposomes made from said amphiphilic compounds are suitable for delivery of a therapeutic substance or a diagnostic agent specifically to a target organ or tissue, or for delivery of a nucleic acid for gene therapy.
-
-
-
-
-
-
-
-
-
搜索结果
10 条记录 (耗时 0.022 秒)
