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公开(公告)号：EP2099789A1
公开(公告)日：2009-09-16
申请号：EP07855439.1
申请日：2007-12-03
发明人： YOAKIM, Christiane , DEROY, Patrick , DUPLESSIS, Martin , GAGNON, Alexandre , GOULET, Sylvie , HÜCKE, Oliver , LEMKE, Christopher , SURPRENANT, Simon
IPC分类号： C07D405/14 , A61K31/4184 , A61K31/4439 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61P31/18 , C07D409/14 , C07D413/14 , C07D417/14
CPC分类号： C07D409/14 , C07D405/14 , C07D413/14 , C07D417/14
摘要： The present invention relates to compounds of formula (I) wherein R1, R2, R3 and R4 are as defined herein, compositions and uses thereof for treating human immunodeficiency virus (HIV) infection. In particular, the present invention provides novel inhibitors of HIV replication, pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HIV infection.
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公开(公告)号：EP1654261A1
公开(公告)日：2006-05-10
申请号：EP04733750.6
申请日：2004-05-19
发明人： LLINAS-BRUNET, Montse , BAILEY, Murray, D. , BHARDWAJ, Punit , BORDELEAU, Josée , FORGIONE, Pasquale , GHIRO, Elise , GORYS, Vida , GOUDREAU, Nathalie , GOULET, Sylvie , HALMOS, Teddy , RANCOURT, Jean
IPC分类号： C07D417/04 , C07K5/08 , A61P31/00
CPC分类号： A61K31/4709 , A61K38/06 , A61K38/212 , C07K5/0808 , C07K5/0827 , Y02A50/463 , A61K2300/00
摘要： Compounds of formula (I): wherein B, X, R3, L0, L1, L2, R2, R1 and RC are defined herein. The compounds are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection.
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公开(公告)号：EP2054388A1
公开(公告)日：2009-05-06
申请号：EP07785026.1
申请日：2007-08-06
发明人： BEAULIEU, Pierre L , COULOMBE, René , FAZAL, Gulrez , GOULET, Sylvie , POIRIER, Martin , RANCOURT, Jean , STAMMERS, Timothy , THAVONEKHAM, Bounkham
IPC分类号： C07D213/62 , A61K31/351 , A61K31/381 , A61K31/415 , A61K31/4184 , A61K31/44 , A61K31/4439 , A61K31/497 , A61K31/5377 , A61P31/14 , C07D231/18 , C07D235/12 , C07D309/12 , C07D333/32 , C07D401/06 , C07D401/12 , C07D413/04 , C07D413/06 , C07D417/06
CPC分类号： C07D213/68 , C07D213/70 , C07D213/71 , C07D213/73 , C07D213/74 , C07D213/79 , C07D213/80 , C07D213/85 , C07D213/89 , C07D215/227 , C07D217/24 , C07D231/18 , C07D235/08 , C07D235/12 , C07D237/14 , C07D239/34 , C07D239/56 , C07D241/20 , C07D241/24 , C07D307/20 , C07D309/12 , C07D333/32 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/12 , C07D413/06 , C07D413/12 , C07D417/06 , C07D417/12 , C07D471/04
摘要： Compounds of formula (I) : wherein X, R2, R3, R5 and R6 are defined herein, are useful as inhibitors of the hepatitis C virus NS5B polymerase.
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公开(公告)号：EP1654261B1
公开(公告)日：2007-11-14
申请号：EP04733750.6
申请日：2004-05-19
发明人： LLINAS-BRUNET, Montse , BAILEY, Murray, D. , BHARDWAJ, Punit , BORDELEAU, Josée , FORGIONE, Pasquale , GHIRO, Elise , GORYS, Vida , GOUDREAU, Nathalie , GOULET, Sylvie , HALMOS, Teddy , RANCOURT, Jean
IPC分类号： C07D417/04 , C07K5/08 , A61P31/00
CPC分类号： A61K31/4709 , A61K38/06 , A61K38/212 , C07K5/0808 , C07K5/0827 , Y02A50/463 , A61K2300/00
摘要： Compounds of formula (I): wherein B, X, R3, L0, L1, L2, R2, R1 and RC are defined herein. The compounds are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection.
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