-
1.发明公开
公开(公告)号：EP1077950A1
公开(公告)日：2001-02-28
申请号：EP99920662.6
申请日：1999-04-14
发明人： BRENNER, Michael , PALLUK, Rainer , WIENRICH, Marion , WEISER, Thomas , CEREDA, Enzo , BIGNOTTI, Maura , PELLEGRINI, Carlo, Maria , SCHIAVI, Giovanni, Battista , CESANA, Raffaele
IPC分类号： C07D239/26 , C07D239/36 , C07D251/22 , C07D253/06 , A61K31/505 , A61K31/53
CPC分类号： C07D239/26 , C07D239/36 , C07D251/16 , C07D253/065
摘要： The invention relates to novel diphenyl-substituted 6-ring-heterocycles of general formula (I), wherein A, X and the radicals R?1, R2, R3, R4 and R5¿ have the meanings given in the description. The invention also relates to methods for producing the inventive compounds and to their use as medicaments.
-
2.发明授权
公开(公告)号：EP1077950B1
公开(公告)日：2004-09-22
申请号：EP99920662.6
申请日：1999-04-14
发明人： BRENNER, Michael , PALLUK, Rainer , WIENRICH, Marion , WEISER, Thomas , CEREDA, Enzo , BIGNOTTI, Maura , PELLEGRINI, Carlo Maria , SCHIAVI, Giovanni, Battista , CESANA, Raffaele
IPC分类号： C07D239/26 , C07D239/36 , C07D251/22 , C07D253/06 , A61K31/505 , A61K31/53
CPC分类号： C07D239/26 , C07D239/36 , C07D251/16 , C07D253/065
-
3.发明公开
公开(公告)号：EP1071670A1
公开(公告)日：2001-01-31
申请号：EP99920661.8
申请日：1999-04-14
发明人： BRENNER, Michael , BECHTEL, Wolf-Dietrich , PALLUK, Rainer , WIENRICH, Marion , WEISER, Thomas , CEREDA, Enzo , BIGNOTTI, Maura , PELLEGRINI, Carlomaria
IPC分类号： C07D249/08 , C07D263/32 , C07D263/38 , C07D233/54 , C07D233/70 , C07D233/78 , C07D271/10 , C07D207/32 , C07D207/44 , C07D231/22
CPC分类号： C07D207/333 , C07D231/12 , C07D231/22 , C07D233/64 , C07D249/08 , C07D261/08 , C07D263/32
摘要： The invention relates to novel diphenyl-substituted 5-ring-heterocycles of general formula (I), wherein A, X and the radicals R?1, R2, R3, R4 and R5¿ have the meanings given in the description. The invention also relates to methods for producing the inventive compounds and to their use as medicaments.
-
4.发明授权
公开(公告)号：EP1071670B1
公开(公告)日：2004-07-07
申请号：EP99920661.8
申请日：1999-04-14
发明人： BRENNER, Michael , BECHTEL, Wolf-Dietrich , PALLUK, Rainer , WIENRICH, Marion , WEISER, Thomas , CEREDA, Enzo , BIGNOTTI, Maura , PELLEGRINI, Carlomaria
IPC分类号： C07D249/08 , C07D263/32 , C07D263/38 , C07D233/54 , C07D233/70 , C07D233/78 , C07D271/10 , C07D207/32 , C07D207/44 , C07D231/22
CPC分类号： C07D207/333 , C07D231/12 , C07D231/22 , C07D233/64 , C07D249/08 , C07D261/08 , C07D263/32
-
公开(公告)号：EP1311471A1
公开(公告)日：2003-05-21
申请号：EP01971870.9
申请日：2001-08-04
发明人： FUCHS, Klaus , STRANSKY, Werner , GRAUERT, Matthias , CARTER, Adrian , GAIDA, Wolfram , WEISER, Thomas , ENSINGER, Helmut
IPC分类号： C07C217/48 , C07C211/35 , C07C211/27 , C07D295/092 , C07D295/125 , A61K31/137 , A61K31/14 , A61K31/40 , A61K31/4453 , A61P9/06 , A61P25/28
CPC分类号： C07D295/125 , C07C211/35 , C07C217/48 , C07C2601/02 , C07C2601/14 , C07C2601/16 , C07D231/12 , C07D233/56 , C07D249/08 , C07D295/092
摘要： The invention relates to compounds of the general formula (1), wherein A, R?1, R2, R3, R4, R5 and R6¿ are defined as in the description and the claims. The invention further relates to a method for producing said compounds and to their use as medicaments. The compounds of formula (1) are used as blockers of the voltage-dependent sodium channel and can be used for diseases that are associated with a functional disorder caused by hyperexcitability.
-
6.发明授权SUBSTITUIERTE 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCIN-10-OLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权取代的1,2,3,4,5,6-六氢-2,6-亚甲基-3- benzazocine-10 OLE，制造方法相同，并且它们作为药物
公开(公告)号：EP1157020B1
公开(公告)日：2002-09-25
申请号：EP00907557.3
申请日：2000-02-12
发明人： GRAUERT, Matthias , BRIEM, Hans , HOFFMANN, Matthias , CARTER, Adrian , WEISER, Thomas , BECHTEL, Wolf-Dietrich , PALLUK, Rainer
IPC分类号： C07D405/06 , A61K31/4748 , A61P25/08 , A61P25/14 , A61P25/18
CPC分类号： C07D405/06
摘要： The invention relates to N-(5-phenyl-tetrahydrofuranyl)methyl-and N-(6-phenyl-tetrahydropyranyl)methyl substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols of general formula (1), to a method for producing them and to their use as medicaments.
-
7.发明公开SUBSTITUIERTE 1,2,3,4,5,6-HEXAHYDRO-2,6-METHANO-3-BENZAZOCIN-10-OLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权取代的1,2,3,4,5,6-六氢-2,6-亚甲基-3- benzazocine-10 OLE，制造方法相同，并且它们作为药物
公开(公告)号：EP1015433A1
公开(公告)日：2000-07-05
申请号：EP98950009.5
申请日：1998-09-09
发明人： GRAUERT, Matthias , CARTER, Adrian , BECHTEL, Wolf-Dietrich , WEISER, Thomas , PALLUK, Rainer , PSCHORN, Uwe
IPC分类号： C07D221/26 , A61K31/435 , A61K31/485
CPC分类号： C07D221/26
摘要： The invention relates to novel substituted 1,2,3,4,5,6-hexahydro-2.6-methano-3-benzazocine-10-oles of general formula (I), and to a method for the production and the use thereof as medicaments.
-
8.发明公开2,3,3A,4,9,9A-HEXAHYDRO-8-HYDROXY-1H-BENZ[F]INDOLE, VERFAHREN ZU IHRER HERSTELLUNG UND IHRE VERWENDUNG ALS ARZNEIMITTEL 有权甲基-2,3,3a，4,9,9a - 六氢-8-羟基-1H-苯并[F]吲哚，其制造方法相同，并且它们作为药物
公开(公告)号：EP1100780A1
公开(公告)日：2001-05-23
申请号：EP99936584.4
申请日：1999-07-22
发明人： GRAUERT, Matthias , HOENKE, Christoph , CARTER, Adrian , BECHTEL, Wolf-Dietrich , WEISER, Thomas , PALLUK, Rainer , PSCHORN, Uwe
IPC分类号： C07D209/60 , A61K31/40
CPC分类号： C07D209/60
摘要： The application relates to substituted 2,3,3a,4,9,9a hexahydro-8-hydroxy-1H-benz[f]indole derivatives, to a method for the production thereof, and to their use as medicaments. The inventive indole derivatives correspond to general formula (1).
-
公开(公告)号：EP1648436A1
公开(公告)日：2006-04-26
申请号：EP04741036.0
申请日：2004-07-15
发明人： WEISER, Thomas , GAIDA, Wolfram , KLINDER, Klaus
IPC分类号： A61K31/137 , A61P25/08
CPC分类号： A61K45/06 , A61K31/137 , A61K31/498 , A61K2300/00
摘要： The invention concerns the use of ambroxol and its pharmaceutically acceptable salts for producing a medicine for treating epilepsy.
-
10.发明公开
公开(公告)号：EP1154983A1
公开(公告)日：2001-11-21
申请号：EP00907556.5
申请日：2000-02-12
发明人： STRANSKY, Werner , GRAUERT, Matthias , CARTER, Adrian , WEISER, Thomas , BECHTEL, Wolf-Dietrich , ENSINGER, Helmut , LOTZ, Ralf, Richard, Hermann , PALLUK, Rainer , PSCHORN, Uwe
IPC分类号： C07C217/48 , C07D295/08 , C07D307/52 , C07D309/14 , C07D233/48 , A61K31/138 , A61K31/4453 , A61P9/06 , A61P25/28
CPC分类号： C07D295/088 , C07C217/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/66 , C07D233/48 , C07D307/52 , C07D309/14
摘要： The invention relates to novel substituted 3-phenoxy or 3-phenylalkyloxy-2-phenyl-propylamines of general formula (1), to methods for producing them and to their use as medicaments.
-
-
-
-
-
-
-
-
-
搜索结果
17 条记录 (耗时 0.017 秒)
