-
公开(公告)号：EP4415659A1
公开(公告)日：2024-08-21
申请号：EP22801624.2
申请日：2022-10-11
CPC分类号： A61F2/9524 , A61F2/2418
-
公开(公告)号：EP2629832A1
公开(公告)日：2013-08-28
申请号：EP11749650.5
申请日：2011-08-16
发明人： RADHAKRISHNAN, Rajesh , LARSEN, Steve , SCHEWE, Scott , FENG, James , WARNER, Robert , FOLAN, Martyn , FLANAGAN, Aiden , CLARKE, John , O'CONNOR, Tim , MALONE, Anthony
IPC分类号： A61M25/10
CPC分类号： A61M25/1027 , A61L29/085 , A61L29/16 , A61L2300/40 , A61L2420/08 , A61M2025/1031 , A61M2025/105 , A61M2025/1075 , A61M2025/1086
摘要： A medical balloon having an inner surface and an outer surface comprising a first coating composition comprising at least one therapeutic agent, the first coating composition disposed on the balloon outer surface and forming an interface between the balloon outer surface and the first coating composition and a second coating composition comprising a bioadhesive, the second coating composition disposed on the first coating composition so as to not affect the interface between the balloon outer surface and the first coating composition, the bioadhesive selected so as to adhere to body tissue, and methods of making the same.
-
3.发明授权
公开(公告)号：EP2190493B1
公开(公告)日：2012-06-27
申请号：EP08833080.8
申请日：2008-09-24
发明人： CLARKE, John , MCMORROW, David , FLANAGAN, Aiden , O'CONNOR, Tim , WEBER, Jan , O'BRIEN, Barry, J.
CPC分类号： A61L31/022 , A61L31/14 , A61L31/16 , A61L2300/00
摘要： An implantable or insertable medical device is provided which includes as components: (a) a substrate component comprising a depression that is at least partially filled with a therapeutic agent-containing material that comprises a first therapeutic agent, and (b) a particulate composition disposed in the depression such that it regulates transport of chemical species between the depression and the exterior of the device upon implantation or insertion of the device into a subject.
-
公开(公告)号：EP2076296A2
公开(公告)日：2009-07-08
申请号：EP07842484.3
申请日：2007-09-14
IPC分类号： A61L31/14
CPC分类号： A61L31/146 , A61F2/82 , A61F2/91 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/626
摘要： A stent having a surface or portion thereof comprising a polymer having a morphology of surface features having a substantially uniform periodicity of about 1 to 50 microns.
-
5.发明公开
公开(公告)号：EP4391970A1
公开(公告)日：2024-07-03
申请号：EP22772701.3
申请日：2022-08-24
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2250/003620130101 , A61F2250/003920130101
-
-
公开(公告)号：EP3681439A1
公开(公告)日：2020-07-22
申请号：EP18766529.4
申请日：2018-08-29
发明人： MCAFEE, Patricia , FLANAGAN, Aiden , O'CONNOR, Tim , WEBER, Jan , JARRAL, Omar
IPC分类号： A61F2/24
-
公开(公告)号：EP3547966A1
公开(公告)日：2019-10-09
申请号：EP17829747.9
申请日：2017-12-01
发明人： O'CONNOR, Tim , O'TOOLE, Pat , O'SULLIVAN, Richard , FEELEY, Marc , GUNNING, Paul , HORGAN, Fergal , SMYTH, Coley , SHANLEY, Sean , LINKE, Axel
IPC分类号： A61F2/24
-
公开(公告)号：EP2231216B1
公开(公告)日：2012-08-08
申请号：EP08862659.3
申请日：2008-12-12
发明人： CLARKE, John T. , O'CONNOR, Tim , XU, Yixin , O'BRIEN, Barry , ARCAND, Ben , SHIPPY, James Lee, III , ATANASOSKA, Liliana , FLANAGAN, Aiden , MCMORROW, Dave , WEBER, Jan , KREMER, John , KUEHLING, Michael , SEIDEL, Dominique
CPC分类号： A61L31/088 , A61L31/16 , A61L2300/45 , A61L2300/61
摘要： A drug-eluting endoprosthesis that includes a bioerodible metal portion and a therapeutic agent. In some aspects, the endoprosthesis includes a plurality of discrete deposits and a plurality of overlying layers each overlying one of the plurality of discrete deposits. Each discrete deposit includes one or more therapeutic agents and each overlying layer includes one or more bioerodible metals. In other aspects, the bioerodible metal portion includes at least two bioerodible metal regions having different electronegativities. The at least two bioerodible metal regions being in electrical contact with each other. The bioerodible metal erodes in a physiological environment to release the therapeutic agent.
-
公开(公告)号：EP2271380A2
公开(公告)日：2011-01-12
申请号：EP09735464.1
申请日：2009-04-17
发明人： FLANAGAN, Aiden , KILCOOLEY, John , O'CONNOR, Tim , O'BRIEN, Barry , SEIDEL, Dominique , KUEHLING, Michael , SCHEUERMANN, Torsten , WEBER, Jan
CPC分类号： A61L29/10 , A61L29/16 , A61L31/082 , A61L31/16 , A61L2300/602 , A61L2300/61
摘要： In one aspect, a medical device has a first configuration and a second configuration, a reservoir containing a therapeutic agent, and a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material. In another aspect, a medical device has a reservoir containing a therapeutic agent, a barrier layer disposed over the reservoir, wherein the barrier layer comprises an inorganic material, and a swellable material disposed between the barrier layer and a surface of the medical device, wherein the swellable material is a material that swells upon exposure to an aqueous environment. In yet another aspect, a medical device has a multi-layered coating having alternating reservoir layers and barrier layers, and a plurality of excavated regions penetrating through at least a partial thickness of the multi-layered coating. In yet another aspect, a medical device has a polymer layer comprising a block co-polymer, wherein the polymer layer contains a therapeutic agent, and a barrier layer disposed over the polymer layer, wherein the barrier layer comprises an inorganic material, and wherein the barrier layer has a plurality of discontinuities. Methods of forming coatings on medical devices and methods of delivering therapeutic agents to body sites are also disclosed.
-
-
-
-
-
-
-
-
-
搜索结果
33 条记录 (耗时 0.017 秒)
