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1.发明公开ORALLY ADMINISTRABLE VIRIDIOFUNGIN DERIVATIVE HAVING ANTI-HCV ACTIVITY 审中-公开具有抗HCV活性的口服给药VIRIDIOFUNGINDERIVAT
公开(公告)号：EP2886530A4
公开(公告)日：2016-01-27
申请号：EP13829884
申请日：2013-08-16
IPC分类号： C07C235/28 , A61K31/192 , A61K31/357 , A61P1/16 , A61P31/14 , A61P43/00 , C07D317/40
CPC分类号： C07D317/36 , A61K31/192 , A61K31/357 , C07C235/28 , C07C235/74 , C07C2601/16 , C07D293/06 , C07D317/34 , C07D317/40
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2.发明公开NOVEL 4-PHENYLAMINO-BENZALDOXIME DERIVATIVE AND USE THEREOF AS MEK INHIBITOR 审中-公开新的4 PHENYLAMINOBENZALDOXIMDERIVATIE和其作为MEK抑制剂的
公开(公告)号：EP1674452A4
公开(公告)日：2007-10-10
申请号：EP04773160
申请日：2004-09-16
发明人： ISSHIKI YOSHIAKI , KOHCHI YASUNORI , HATTORI KAZUO , SHIMMA NOBUO , MIWA MASANORI , INAGAKI NAOHITO , IIKURA HITOSHI , MATSUBARA YASUAKI
IPC分类号： C07C259/10 , A61K31/166 , A61K45/00 , A61P1/00 , A61P1/16 , A61P1/18 , A61P3/10 , A61P9/00 , A61P9/04 , A61P9/08 , A61P9/10 , A61P11/00 , A61P11/06 , A61P13/08 , A61P15/00 , A61P17/06 , A61P19/02 , A61P19/04 , A61P25/28 , A61P29/00 , A61P31/04 , A61P31/12 , A61P31/18 , A61P35/00 , A61P37/00 , A61P37/06 , A61P43/00 , C07C229/58 , C07C251/48 , C07C311/04 , C07C317/18 , C07C323/12 , C07D207/08 , C07D207/26 , C07D207/27 , C07D211/46 , C07D213/30 , C07D233/32 , C07D233/34 , C07D233/54 , C07D233/64 , C07D263/32 , C07D295/08 , C07D295/088 , C07D295/155 , C07F7/18
CPC分类号： C07D207/08 , A61K31/166 , C07C259/10 , C07C311/04 , C07C317/18 , C07C323/12 , C07C2601/02 , C07D207/27 , C07D211/46 , C07D213/30 , C07D233/32 , C07D233/64 , C07D263/32 , C07D295/088 , C07D295/155 , C07F7/1856
摘要： A compound of the present invention and pharmaceutically acceptable salts thereof are represented by the following general formula (1). (1) (In the formula (1), the definitions of R1, R2, R3, R4, R5, R6, Q, R8 and R9 are the same as those defined in the description.)
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3.发明公开PROCESS FOR PRODUCTION OF 2,3,4-TRIFLUORO-5-(IODO OR BROMO)BENZOIC ACID 有权用于生产2,3,4-三氟-5-（IOD或溴）苯甲酸
公开(公告)号：EP1870392A4
公开(公告)日：2009-04-15
申请号：EP06731258
申请日：2006-04-06
IPC分类号： C07C51/363 , C07B61/00 , C07C63/70
CPC分类号： C07C51/363 , C07C63/70
摘要： A process for producing 2,3,4-trifluoro-5-(iodo or bromo)benzoic acid, the process comprising a haloganation step in which 2,3,4-trifluorobenzoic acid is iodinated or brominated directly with an iodinating agent or brominating agent in a reaction solvent in the presence of an oxidizing agent. This process can produce 2,3,4-trifluoro-5-(iodo or bromo)benzoic acid in a simple manner in high yield, at high purity and with high stereoselectivity.
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公开(公告)号：EP1780197A4
公开(公告)日：2008-06-25
申请号：EP05767184
申请日：2005-07-26
发明人： ISSHIKI YOSHIAKI , KOHCHI YASUNORI , MIZUGUCHI EISAKU , IIKURA HITOSHI , MATSUBARA YASUAKI , TSUJII SHINJI , SHIMMA NOBUO , MIWA MASANORI , AIDA SATOSHI , KOHCHI MASAMI , MURATA TAKESHI , ASO KOSUKE
IPC分类号： C07C259/10 , A61K31/166 , A61K31/4015 , A61K31/4164 , A61K31/42 , A61K31/421 , A61K31/45 , C07C11/24 , C07C317/04 , C07C323/12 , C07D207/27 , C07D211/76 , C07D233/64 , C07D239/10 , C07D261/04 , C07D263/24 , C07D265/02 , C07D265/32 , C07D273/01 , C07D295/08
CPC分类号： C07C259/10 , C07C317/18 , C07C323/12 , C07D207/27 , C07D211/76 , C07D239/10 , C07D261/04 , C07D263/22 , C07D265/02 , C07D265/32 , C07D273/00
摘要： Disclosed are a compound and pharmaceutically acceptable salts thereof represented by the general formula (1) below. (In the formula (1), R1, R2, R3, R4 and X are the same as R1, R2, R3, R4 and X defined in the description.)
摘要翻译： 公开了由以下通式（1）表示的化合物及其药学上可接受的盐。 （式（1）中，R1，R2，R3，R4和X与说明书中定义的R1，R2，R3，R4和X相同。）
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