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公开(公告)号:EP2036895A4
公开(公告)日:2010-12-22
申请号:EP07744100
申请日:2007-05-25
发明人: TSUKUDA TAKUO , KAWASAKI KEN-ICHI , KOMIYAMA SUSUMU , ISSHIKI YOSHIAKI , SHIRATORI YASUHIKO , HASEGAWA KIYOSHI , FUKAMI TAKAAKI , MIURA TAKAAKI , ONO NAOMI , YAMAZAKI TOSHIKAZU , NA YOUNG-JUN , YOON DONG-OH , KIM SUNG-JIN
IPC分类号: C07D239/47 , A61K31/505 , A61K31/506 , A61K31/53 , A61K31/5377 , A61P1/16 , A61P3/04 , A61P9/10 , A61P11/00 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P35/04
CPC分类号: C07D251/16 , C07D239/47 , C07D239/48 , C07D401/12 , C07D403/10 , C07D403/12 , C07D405/04 , C07D405/14 , C07D409/04 , C07D413/14 , C07D417/12 , C07D417/14
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2.PROCESS FOR PRODUCING COMPOUND WITH ANTI-HCV POTENCY AND INTERMEDIATE FOR USE THEREIN 审中-公开
标题翻译: 方法在其中产生具有抗HCV行动和使用连接中间体公开(公告)号:EP1857456A4
公开(公告)日:2011-03-09
申请号:EP06713828
申请日:2006-02-16
发明人: KATO TATSUYA , KOMIYAMA SUSUMU , MIZUTANI AKEMI , MAKINO TOSHIHIKO , KAWASAKI KENICHI , TSUKUDA TAKUO , FUKUDA HIROSHI , KIMURA NOBUAKI
IPC分类号: C07D413/06 , C07C231/02 , C07C233/76 , C07F7/18
CPC分类号: C07D413/06 , C07C231/12 , C07F7/1852 , C07F7/1856 , C07C235/76
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3.ORALLY ADMINISTRABLE VIRIDIOFUNGIN DERIVATIVE HAVING ANTI-HCV ACTIVITY 审中-公开
标题翻译: 具有抗HCV活性的口服给药VIRIDIOFUNGINDERIVAT公开(公告)号:EP2886530A4
公开(公告)日:2016-01-27
申请号:EP13829884
申请日:2013-08-16
IPC分类号: C07C235/28 , A61K31/192 , A61K31/357 , A61P1/16 , A61P31/14 , A61P43/00 , C07D317/40
CPC分类号: C07D317/36 , A61K31/192 , A61K31/357 , C07C235/28 , C07C235/74 , C07C2601/16 , C07D293/06 , C07D317/34 , C07D317/40
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公开(公告)号:EP2119718A4
公开(公告)日:2010-12-15
申请号:EP08721047
申请日:2008-02-29
发明人: SHIMMA NOBUO , TSUKUDA TAKUO , KOYANO HIROSHI , SUDA ATSUSHI , HAYASE TADAKATSU , HADA KIHITO , KAWASAKI KEN-ICHI , KOMIYAMA SUSUMU , ONO NAOMI , YAMAZAKI TOSHIKAZU , SAITOH RYOICHI , KOHCHI MASAMI , HASEGAWA KIYOSHI
IPC分类号: C07D497/08 , A61K31/529 , A61K31/53 , A61K31/5377 , A61P1/16 , A61P9/10 , A61P11/00 , A61P13/12 , A61P17/00 , A61P17/02 , A61P19/02 , A61P21/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/00 , A61P35/00 , A61P35/02 , A61P37/02 , A61P37/06
CPC分类号: C07D497/08 , C07D513/08 , C07D513/18 , C07D513/20
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5.
公开(公告)号:EP1661882A4
公开(公告)日:2007-01-31
申请号:EP04747271
申请日:2004-07-09
发明人: SUDOH MASAYUKI , TSUKUDA TAKUO , MASUBUCHI MIYAKO , KAWASAKI KENICHI , MURATA TAKESHI , WATANABE FUMIO , FUKUDA HIROSHI , KOMIYAMA SUSUMU , HAYASE TADAKATSU
IPC分类号: C07C231/02 , A61K31/195 , A61K31/201 , A61K31/216 , A61K31/405 , A61P31/12 , C07C69/738 , C07C235/76 , C07D303/12 , C07D317/18
CPC分类号: A61K31/195 , A61K31/216 , A61K31/405 , C07C235/76
摘要: A compound which has high HCV replication inhibitory activity and is hence useful in the prevention of and treatments for viral infectious diseases, especially liver diseases attributable to HCV infection; a process for producing the compound; an intermediate useful for the production; and a medicinal composition containing the compound. The compound is any of a compound represented by the formula (I): [wherein A represents -(CH2)n-, etc.; B represents -(C=O)-, etc.; D represents -(CH2)m-R', etc.; E represents hydrogen, etc.; G represents -(CH2)p-J, etc.; bond Q represents a single bond or double bond; and R1, R2, and R3 are the same or different and each represents hydrogen, etc.], a prodrug thereof, and a pharmaceutically acceptable salt of either.
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