公开(公告)号：EP1131113B1

公开(公告)日：2005-07-20

申请号：EP99972115.2

申请日：1999-11-15

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ,  INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  Kerckhoff-Klinik GmbH

发明人： LE MOEL, Alain ,  BETZ, Natacha ,  BUREAU, Christophe ,  DENIAU, Guy ,  BAQUEY, Charles ,  DELERIS, Gérard ,  HABERBOSCH, Werner

IPC分类号： A61L31/10 ,  A61L31/16

CPC分类号： A61L33/0029 ,  A61F2/06 ,  A61F2/82 ,  A61L27/28 ,  A61L27/34 ,  A61L27/54 ,  A61L2300/258 ,  A61L2300/406 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2400/18

摘要： The invention concerns a bioactive prosthesis comprising a support coated with a polymer layer with reactive functions, and a bioactive substance fixed on the prosthesis via said reactive functions so as to be gradually released on a site for implanting the prosthesis. Such prostheses are useful in the field of cardiology to avoid for example restenosis resulting from implantation of stents in coronary arteries.

公开(公告)号：EP1543080B1

公开(公告)日：2010-03-03

申请号：EP03773827.5

申请日：2003-08-25

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： BUREAU, Christophe ,  DENIAU, Guy ,  PALACIN, Serge

IPC分类号： C09D5/44 ,  C25D13/08

CPC分类号： C09D5/4476 ,  Y10T29/49126 ,  Y10T29/49128 ,  Y10T29/49165

公开(公告)号：EP1131113A1

公开(公告)日：2001-09-12

申请号：EP99972115.2

申请日：1999-11-15

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE ,  INSTITUT NATIONAL DE LA SANTE ET DE LARECHERCHE MEDICALE (INSERM) ,  Justus-Liebig- Universitat Giessen

发明人： LE MOEL, Alain ,  BETZ, Natacha ,  BUREAU, Christophe ,  DENIAU, Guy ,  BAQUEY, Charles ,  DELERIS, Gérard ,  HABERBOSCH, Werner

IPC分类号： A61L31/10 ,  A61L31/16

CPC分类号： A61L33/0029 ,  A61F2/06 ,  A61F2/82 ,  A61L27/28 ,  A61L27/34 ,  A61L27/54 ,  A61L2300/258 ,  A61L2300/406 ,  A61L2300/41 ,  A61L2300/416 ,  A61L2300/42 ,  A61L2400/18

摘要： The invention concerns a bioactive prosthesis comprising a support coated with a polymer layer with reactive functions, and a bioactive substance fixed on the prosthesis via said reactive functions so as to be gradually released on a site for implanting the prosthesis. Such prostheses are useful in the field of cardiology to avoid for example restenosis resulting from implantation of stents in coronary arteries.

公开(公告)号：EP1595001B1

公开(公告)日：2007-05-02

申请号：EP04710908.7

申请日：2004-02-13

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： VIEL, Pascal ,  AMEUR, Sami ,  BUREAU, Christophe

IPC分类号： C23C14/02 ,  B05D7/00

CPC分类号： C25D15/00 ,  C09D5/4407 ,  C23C26/00 ,  C25D3/38 ,  C25D5/34 ,  C25D5/54 ,  Y10T428/12493

摘要： The invention relates to a method of depositing or fixing materials to surfaces. More specifically, the invention relates to a method of coating a surface with first and second materials, comprising the following steps consisting in: depositing a first material on the surface; inserting precursor molecules of a second material into the first material deposited on the surface; and transforming the aforementioned precursor molecules of the second material into the second material, such that said second material forms on the surface to be coated and inside the first material deposited thereon. The inventive method can be used to deposit any type of material on any type of surface.

公开(公告)号：EP1551928A1

公开(公告)日：2005-07-13

申请号：EP03762703.1

申请日：2003-06-16

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： BUREAU, Christophe ,  MOUANDA, Brigitte ,  AMEUR, Sami ,  CHARLIER, Julienne ,  PALACIN, Serge

IPC分类号： C09D5/44 ,  C25D13/04

CPC分类号： C09D5/4476

摘要： The invention concerns a solid support comprising a functionalized electricity conductor or semiconductor surface coated with a functionalized electrografted organic layer wherein at least 90 % of the number of functional groups of interest is accessible. The invention also concerns the method for preparing such a support and uses thereof, in particular as adhesive primer for fixing molecules of interest or objects bearing a complementary function (molecular adhesive).

公开(公告)号：EP1315565B1

公开(公告)日：2004-10-20

申请号：EP01965373.2

申请日：2001-08-29

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： BUREAU, Christophe ,  LEDERF, Franck ,  VIEL, Pascal ,  DESCOURS, Francis

IPC分类号： B01J45/00 ,  B01J20/32 ,  B01J47/12 ,  C02F1/26

CPC分类号： B01J45/00 ,  B01J20/226 ,  B01J20/264 ,  B01J20/28011 ,  B01J20/3204 ,  B01J20/327 ,  B01J20/3276 ,  B01J20/3278 ,  B01J20/3297 ,  B01J20/3425 ,  B01J20/3475 ,  B01J47/12 ,  C02F1/285 ,  C02F2101/20 ,  C02F2103/16 ,  G21F9/12

公开(公告)号：EP1425108A2

公开(公告)日：2004-06-09

申请号：EP02774884.7

申请日：2002-08-27

申请人： Commissariat A L'Energie Atomique

发明人： BUREAU, Christophe ,  LEVY, Edouard ,  VIEL, Pascal

IPC分类号： B05D1/00

CPC分类号： H01B1/12 ,  B05D5/12 ,  C09D5/4476

摘要： The present invention relates to a process for grafting and growing a conductive organic film on(to) an electrically conductive or semiconductive surface in which the grafting and growing of the film are performed simultaneously by electro-reduction of a diazonium salt that is a precursor of the said film on(to) the said surface cathodically polarized at a potential greater than or equal, in absolute value, to the electro-reduction potential of the diazonium salt relative to a reference electrode. The invention finds an application especially in the protection of surfaces, the manufacture of localized conductive coatings, of chemical sensors in the fields of chemistry and molecular biology, the manufacture of biomedical equipment, etc.

公开(公告)号：EP1687463B1

公开(公告)日：2007-04-25

申请号：EP04787470.6

申请日：2004-09-28

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： BUREAU, Christophe ,  GONZALEZ, José ,  DENIAU, Guy

IPC分类号： C25D13/08 ,  C08F2/58 ,  C09D5/44

CPC分类号： C09D5/4476 ,  C25D9/02 ,  Y10T428/265

摘要： The invention relates to a method for forming a polymer film on a surface that conducts or semiconducts electricity by means of electrografting. Said method uses an electrolytic solution containing a selected quantity of Brönsted acid. The invention also relates to the electrically conductive or semiconductive surfaces obtained by means of said method.

公开(公告)号：EP1543080A2

公开(公告)日：2005-06-22

申请号：EP03773827.5

申请日：2003-08-25

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： BUREAU, Christophe ,  DENIAU, Guy ,  PALACIN, Serge

IPC分类号： C09D5/44 ,  C25D13/08

CPC分类号： C09D5/4476 ,  Y10T29/49126 ,  Y10T29/49128 ,  Y10T29/49165

摘要： The invention relates to a method of coating a simple or complex, conducting or semiconducting surface with an organic film using at least one precursor of said organic film. The invention is characterised in that the surface is coated with the organic film through the initiated electro-grafting of said at least one precursor onto the surface by performing at least one potential scanning on the surface such that, at every point of the surface, the maximum potential of each scanning of potentials, in absolute value and in relation to a reference electrode, is greater than or equal to the potential value (Vbloc) from which the curves of a graphic representation, expressing the quantity of electro-grafted precursor on a surface identical to said surface according to the number of potential scannings, all overlap and are independent of potential Vbloc.

公开(公告)号：EP1425108B1

公开(公告)日：2007-05-02

申请号：EP02774884.7

申请日：2002-08-27

申请人： COMMISSARIAT A L'ENERGIE ATOMIQUE

发明人： BUREAU, Christophe ,  LEVY, Edouard ,  VIEL, Pascal

IPC分类号： B05D1/00

CPC分类号： H01B1/12 ,  B05D5/12 ,  C09D5/4476

摘要： The present invention relates to a process for grafting and growing a conductive organic film on(to) an electrically conductive or semiconductive surface in which the grafting and growing of the film are performed simultaneously by electro-reduction of a diazonium salt that is a precursor of the said film on(to) the said surface cathodically polarized at a potential greater than or equal, in absolute value, to the electro-reduction potential of the diazonium salt relative to a reference electrode. The invention finds an application especially in the protection of surfaces, the manufacture of localized conductive coatings, of chemical sensors in the fields of chemistry and molecular biology, the manufacture of biomedical equipment, etc.