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公开(公告)号：EP1442112A4
公开(公告)日：2009-02-25
申请号：EP02799574
申请日：2002-09-09
申请人： CYNTELLECT INC
IPC分类号： C12N15/09 , C12M1/00 , C12M1/34 , C12M1/42 , C12M3/00 , C12N5/00 , C12N5/06 , C12N13/00 , C12N15/10 , C12N15/87 , G01N33/50 , G01N33/569 , C12N1/18 , G01N33/48
CPC分类号： C12N13/00 , C12M35/02 , C12M47/06 , C12N5/0087 , C12N5/0093 , C12N15/1034 , C12N15/87 , G01N33/5005 , G01N33/5091 , G01N33/56966
摘要： Optoinjection method for transiently permeabilizing a target cell by (a) illuminating a population of cells contained in a frame; (b) detecting at least one property of light directed from the frame; (c) locating a target cell by the property of light; and (d) irradiating the target cell with a pulse (See Figure 9) of radiation.
摘要翻译： （a）照射包含在框架中的细胞群体的瞬时透化靶细胞的Optoinjection方法; （b）检测从所述框架引导的光的至少一个属性; （c）通过光的属性来定位目标细胞; 和（d）用辐射的脉冲（见图9）照射靶细胞。
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2.发明公开METHOD AND DEVICE FOR SELECTIVELY TARGETING CELLS WITHIN A THREE -DIMENSIONAL SPECIMEN 有权方法和装置选择性旨在细胞在三维COPY
公开(公告)号：EP1344181A4
公开(公告)日：2008-12-03
申请号：EP01992423
申请日：2001-10-24
申请人： CYNTELLECT INC
IPC分类号： C12N15/09 , G06K9/00 , A61N5/06 , A61N5/067 , A61N5/10 , C12M1/00 , C12M1/42 , C12Q1/04 , G01N15/14
CPC分类号： G06K9/00127 , A61N5/062 , A61N5/1069 , A61N2005/067 , G01N15/1468 , G01N15/1475 , G01N2015/1415 , G01N2015/144 , G01N2015/1443 , G01N2015/1445 , G01N2015/1452 , G01N2015/1472 , G01N2015/149
摘要： The invention provides an apparatus for electromagnetically affecting a particle of interest in a specimen (600). The apparatus includes a stage (500) capable of supporting the specimen, a detector including at least one camera (450A) , wherein the detector is capable of resolving a particle of interest within the specimen (600) means for locating the particle of interest in three dimension, a means for focusing electromagnetic radiation to a focal volume within the specimen; and a means for adjusting the relative positions of the stage and electromagnetic radiation focusing means, thereby positioning the particle of interest within the focal volume.
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