专利检索 ap:("Centre National de la Recherche Scientifique" OR "Universite de Nantes" OR "INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)") AND inv:"JOSSE, Solen" 第 1 页

1.

发明授权
COMPOSE PHOSPHOCALCIQUE MODIFIE, COMPOSITION INJECTABLE LE CONTENANT 有权
标题翻译：改性钙磷酸盐化合物和组合物含有该注射用

公开(公告)号：EP1480687B1

公开(公告)日：2009-02-11

申请号：EP03717407.5

申请日：2003-02-18

申请人： CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , UNIVERSITE DE NANTES , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)

发明人： BUJOLI, Bruno , JOSSE, Solen , GUICHEUX, Jérôme , JANVIER, Pascal , BOULER, Jean-Michel , DACULSI, Guy

IPC分类号： A61L27/12 , A61L27/54

CPC分类号： A61L27/12 , A61L27/54 , A61L2300/216 , A61L2300/432 , A61L2300/602

摘要： The invention concerns a phosphocalcic compound modified by a gem-bisphosphonic acid or one of its salts, a method for preparing same, as well as its use for preparing an injectable composition. The modified phosphocalcic compound is obtained by adding a gem-bisphosphonic acid or one of its alkali metal or alkaline earth salts to a suspension of a precursor phosphocalcic compound in ultra-pure water, while stirring the reaction medium at room temperature, then in recovering by centrifuging the formed compound. Said compound is useful for making an injectable composition, for use in the treatment of bone remodeling equilibrium.

2.

发明公开
COMPOSE PHOSPHOCALCIQUE MODIFIE, COMPOSITION INJECTABLE LE CONTENANT 有权
标题翻译：改性钙磷酸盐化合物和组合物含有该注射用

公开(公告)号：EP1480687A1

公开(公告)日：2004-12-01

申请号：EP03717407.5

申请日：2003-02-18

申请人： Centre National de la Recherche Scientifique , Universite de Nantes , INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)

发明人： BUJOLI, Bruno , JOSSE, Solen , GUICHEUX, Jérôme , JANVIER, Pascal , BOULER, Jean-Michel , DACULSI, Guy

IPC分类号： A61L27/12 , A61L27/54

CPC分类号： A61L27/12 , A61L27/54 , A61L2300/216 , A61L2300/432 , A61L2300/602

摘要： The invention concerns a phosphocalcic compound modified by a gem-bisphosphonic acid or one of its salts, a method for preparing same, as well as its use for preparing an injectable composition. The modified phosphocalcic compound is obtained by adding a gem-bisphosphonic acid or one of its alkali metal or alkaline earth salts to a suspension of a precursor phosphocalcic compound in ultra-pure water, while stirring the reaction medium at room temperature, then in recovering by centrifuging the formed compound. Said compound is useful for making an injectable composition, for use in the treatment of bone remodeling equilibrium.