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公开(公告)号：EP4284516A1
公开(公告)日：2023-12-06
申请号：EP22704691.9
申请日：2022-01-28
申请人： Compugen Ltd. , White, Mark , Barbiro, Inbal , Vaknin, Ilan , Wool, Assaf , Levine, Zurit
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公开(公告)号：EP2167534B1
公开(公告)日：2012-07-04
申请号：EP08826161.5
申请日：2008-07-11
申请人： Compugen Ltd.
发明人： SHEMESH, Ronen , LEVINE, Zurit , TOPORIK, Amir , HERMESH, Chen , KLIGER, Yossef , GOFER, Eyal , WOOL, Assaf , DAHARY, Dvir , COHEN, Yossi
CPC分类号： C07K14/472 , A61K38/00 , C07K7/06 , C07K14/47 , C07K14/78 , C07K16/18 , C07K2317/34
摘要： Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
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公开(公告)号：EP2167534A2
公开(公告)日：2010-03-31
申请号：EP08826161.5
申请日：2008-07-11
申请人： Compugen Ltd.
发明人： SHEMESH, Ronen , LEVINE, Zurit , TOPORIK, Amir , HERMESH, Chen , KLIGER, Yossi , GOFER, Eyal , WOOL, Assaf , DAHARY, Dvir , COHEN, Yossi
CPC分类号： C07K14/472 , A61K38/00 , C07K7/06 , C07K14/47 , C07K14/78 , C07K16/18 , C07K2317/34
摘要： Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
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公开(公告)号：EP2064234B1
公开(公告)日：2011-11-02
申请号：EP07875175.7
申请日：2007-09-18
申请人： Compugen Ltd.
发明人： COHEN, Yossi , SHEMESH, Ronen , TOPORIK, Amir , LEVINE, Zurit , WOOL, Assaf , DAHARY, Dvir , HECHT, Iris , BEIMAN, Merav , ROTMAN, Galit , AYALON-SOFFER, Michal
IPC分类号： C07K14/43
摘要： Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
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公开(公告)号：EP2240196A2
公开(公告)日：2010-10-20
申请号：EP09703833.5
申请日：2009-01-22
申请人： Compugen Ltd.
发明人： KLIGER, Yossef , LEVY, Ofer , BORUKHOV, Itamar , WOOL, Assaf , SCHREIBER, Ehud , AMIR, Anat , LEVINE, Zurit , TIRAN, Zohar , OREN, Anat , TOPORIK, Amir
IPC分类号： A61K38/17 , C07K14/775 , C07K16/18
CPC分类号： C07K14/775 , A61K38/00
摘要： The subject invention provides clusterin-derived peptides or homologs or derivatives thereof, pharmaceutical composition comprising them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins comprising them.
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6.发明公开
公开(公告)号：EP2675919A1
公开(公告)日：2013-12-25
申请号：EP12746695.1
申请日：2012-02-12
申请人： Compugen Ltd.
发明人： PINCHAS, Akiva , EDELHEIT-FLOHR, Sarit , BAZAK, Lily , LEVINE, Zurit , TOPORIK, Amir , LEVY, Ofer , ZEKHARYA, Tomer , WOOL, Assaf
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/156
摘要： The present invention discloses markers useful in predicting the responsiveness of a subject having, or at risk of developing rheumatoid arthritis (RA) to treatment with anti-TNF agents. Particularly, the present invention discloses the allelic configuration of the CD6 gene and/or the STXBP6 gene which is indicative of the degree of responsiveness to anti-TNFalpha treatment of RA.
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公开(公告)号：EP2315775A2
公开(公告)日：2011-05-04
申请号：EP09787476.2
申请日：2009-07-20
申请人： Compugen Ltd.
发明人： KLIGER, Yossef , BORUKHOV, Itamar , LEVY, Ofer , TIRAN, Zohar , WOOL, Assaf , SCHREIBER, Ehud , AMIR, Anat , LEVINE, Zurit , TOPORIK, Amir
IPC分类号： C07K14/515
CPC分类号： C07K14/515 , A61K38/14 , A61K38/1891 , A61K45/06 , C07K9/00 , C07K9/001
摘要： In at least some embodiments, the subject invention provides angiopoietin-derived peptides or homologs or derivatives thereof, pharmaceutical composition comprising them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins comprising them.
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公开(公告)号：EP2064234A2
公开(公告)日：2009-06-03
申请号：EP07875175.7
申请日：2007-09-18
申请人： Compugen Ltd.
发明人： COHEN, Yossi , SHEMESH, Ronen , TOPORIK, Amir , LEVINE, Zurit , WOOL, Assaf , DAHARY, Dvir , HECHT, Iris , BEIMAN, Merav , ROTMAN, Galit , AYALON-SOFFER, Michal
IPC分类号： C07K14/43
摘要： Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating disorders associated with G-protein coupled receptor activation.
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9.发明公开METHODS OF IDENTIFYING PUTATIVE GENE PRODUCTS BY INTERSPECIES SEQUENCE COMPARISON AND BIOMOLECULAR SEQUENCES UNCOVERED THEREBY 审中-公开一种用于识别假定基因BY种间的序列比较和THAT DISCOVERED生物分子序列
公开(公告)号：EP1716227A2
公开(公告)日：2006-11-02
申请号：EP05703150.2
申请日：2005-01-27
申请人： Compugen Ltd.
发明人： SOREK, Rotem , POLLOCK, Sarah , DIBER, Alex , LEVINE, Zurit , NEMZER, Sergey , KOL, Guy , WOOL, Assaf , HAVIV, Ami , COHEN, Yuval , COHEN, Yossi , SHEMESH, Ronen , SAVITSKY, Kinneret
IPC分类号： C12N1/00
CPC分类号： G06F19/22
摘要： A method of identifying alternatively spliced exons is provided. The method comprising, scoring each of a plurality of exon sequences derived from genes of a species according to at least one sequence parameter, wherein exon sequences of the plurality of exon sequences scoring above a predetermined threshold represent alternatively spliced exons, thereby identifying the alternatively spliced exons.
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