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公开(公告)号：EP1731613A2
公开(公告)日：2006-12-13
申请号：EP06113394.8
申请日：2000-07-05
发明人： Burke, Kevin , Weissenborn, Anke , Hädrich (b. Möckel), Bettina , Sahm, Hermann , Eggeling, Lothar , Stapleton, Cliona , McCormack, Ashling , Moritz, Bernd , Dunican, L.K.
CPC分类号： C12N9/0006 , C12N9/1022 , C12P13/06 , C12P13/08
摘要： Isolated polynucleotide from coryneform bacteria, comprising a polynucleotide which encodes a polypeptide comprising the amino acid sequence of SEQ ID No. 2.
摘要翻译： 来自棒状细菌的分离的多核苷酸，包含编码包含SEQ ID No.2的氨基酸序列的多肽的多核苷酸。
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公开(公告)号：EP1731613A3
公开(公告)日：2009-03-11
申请号：EP06113394.8
申请日：2000-07-05
发明人： Burke, Kevin , Weissenborn, Anke , Hädrich (b. Möckel), Bettina , Sahm, Hermann , Eggeling, Lothar , Stapleton, Cliona , McCormack, Ashling , Moritz, Bernd , Dunican, L.K.
CPC分类号： C12N9/0006 , C12N9/1022 , C12P13/06 , C12P13/08
摘要： Isolated polynucleotide from coryneform bacteria, comprising a polynucleotide which encodes a polypeptide comprising the amino acid sequence of SEQ ID No. 2.
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3.发明公开Cloning and uses of a novel nucleotide sequence coding for glucose-6-phosphate isomerase (gpi) from bacteria 有权使用新的葡萄糖-6-磷酸异构酶基因的克隆和核苷酸序列包含（GPI），该细菌
公开(公告)号：EP1087015A3
公开(公告)日：2003-07-09
申请号：EP00118052.0
申请日：2000-08-23
发明人： Dunican, L. K., Prof. , McCormback, Ashling , Stapelton, Cliona , Burke, Kevin , O'Donohue, Michael , Marx, Achim, Dr. , Möckel, Bettina, Dr.
CPC分类号： C12Y503/01009 , C12N9/92 , C12P13/08 , C12P13/227
摘要： Isolated polynucleotide containing a polynucleotide sequence selected from the group a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2, b) polynucleotide which codes for a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide containing at least 15 successive bases of the polynucleotide sequence of a), b) or c), and process for increasing metabolic flux through the pentose phosphate cycle by attenuating the pgi gene.
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4.发明授权Cloning and use of a novel nucleotide sequence coding for glucose-6-phosphate isomerase (gpi) from bacteria 有权克隆和使用编码细菌葡萄糖-6-磷酸异构酶的新型核苷酸序列（GPI）
公开(公告)号：EP1087015B1
公开(公告)日：2010-11-03
申请号：EP00118052.0
申请日：2000-08-23
发明人： Dunican, L. K., Prof. , McCormback, Ashling , Stapelton, Cliona , Burke, Kevin , O'Donohue, Michael , Marx, Achim, Dr. , Möckel, Bettina, Dr.
CPC分类号： C12Y503/01009 , C12N9/92 , C12P13/08 , C12P13/227
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5.发明公开Cloning and uses of a novel nucleotide sequence coding for glucose-6-phosphate isomerase (gpi) from bacteria 有权克隆和使用编码细菌葡萄糖-6-磷酸异构酶的新型核苷酸序列（GPI）
公开(公告)号：EP1087015A2
公开(公告)日：2001-03-28
申请号：EP00118052.0
申请日：2000-08-23
发明人： Dunican, L. K., Prof. , McCormback, Ashling , Stapelton, Cliona , Burke, Kevin , O'Donohue, Michael , Marx, Achim, Dr. , Möckel, Bettina, Dr.
CPC分类号： C12Y503/01009 , C12N9/92 , C12P13/08 , C12P13/227
摘要： Isolated polynucleotide containing a polynucleotide sequence selected from the group
a) polynucleotide which is at least 70% identical to a polynucleotide which codes for a polypeptide containing the amino acid sequence of SEQ ID no. 2,
b) polynucleotide which codes for a polypeptide which contains an amino acid sequence which is at least 70% identical to the amino acid sequence of SEQ ID no. 2,
c) polynucleotide which is complementary to the polynucleotides of a) or b), and
d) polynucleotide containing at least 15 successive bases of the polynucleotide sequence of a), b) or c),
and process for increasing metabolic flux through the pentose phosphate cycle by attenuating the pgi gene.摘要翻译： 分离的多核苷酸包含选自下组的选定的多核苷酸序列）的多核苷酸的所有其是至少70％相同，其编码含有SEQ ID NO：2的氨基酸序列的多肽。2，B）多核苷酸，其包含编码多肽的多核苷酸 到氨基酸2氨基酸序列，其至少70％相同于SEQ ID NO：2的氨基酸序列。，C）多核苷酸，其互补的多核苷酸）或b），以及d）多核苷酸含有至少15个连续碱基 的多核苷酸序列），b）或c），以及用于通过衰减pgi基因通过戊糖磷酸循环增加代谢通量处理。
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