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公开(公告)号：EP3768731A1
公开(公告)日：2021-01-27
申请号：EP19714947.9
申请日：2019-03-18
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3.发明公开
公开(公告)号：EP3204351A1
公开(公告)日：2017-08-16
申请号：EP15791809.5
申请日：2015-10-08
IPC分类号： C07C209/66 , C07C221/00 , C07C231/12
CPC分类号： C07C209/18 , B01J31/2295 , B01J2231/44 , B01J2531/824 , C07B43/04 , C07C209/66 , C07C213/02 , C07C221/00 , C07C227/08 , C07C231/12 , C07C253/30 , C07D213/74 , C07D295/023 , C07D295/033 , C07D317/58 , C07D317/66 , C07C211/54 , C07C211/48 , C07C211/55 , C07C211/56 , C07C223/06 , C07C237/40 , C07C217/84 , C07C229/60 , C07C255/58
摘要： The present disclosure describes a method of coupling a first compound to a second compound, the method comprising: providing the first compound having a fluorosulfonate substituent; providing the second compound comprising an amine; and reacting the first compound and the second compound in a reaction mixture, the reaction mixture including a catalyst having at least one group 10 atom, the reaction mixture under conditions effective to couple the first compound to the second compound. The present disclosure further describes a one-pot method for coupling a first compound to a second compound.
摘要翻译： 本公开描述了将第一化合物偶联至第二化合物的方法，所述方法包括：提供具有氟磺酸酯取代基的第一化合物; 提供包含胺的第二化合物; 以及使第一化合物和第二化合物在反应混合物中反应，所述反应混合物包含具有至少一个第10族原子的催化剂，反应混合物在有效将第一化合物偶联至第二化合物的条件下。 本公开进一步描述了用于将第一化合物偶联至第二化合物的一锅法。
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公开(公告)号：EP3337808A1
公开(公告)日：2018-06-27
申请号：EP16754631.6
申请日：2016-08-12
IPC分类号： C07F5/02
CPC分类号： C07F5/025 , B01J23/755 , C07C303/08 , C07C309/81 , C07C309/86
摘要： In one aspect, there is provided a method of coupling an aromatic or vinylic compound having a fluorosulfonate substituent to a boron-containing compound. In another aspect, there is provided a method of coupling an aromatic or vinylic compound having a hydroxyl substituent to a boron-containing compound in a one-pot reaction.
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5.发明授权METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND 有权将第一种芳香化合物与第二种芳香化合物偶联的方法
公开(公告)号：EP3122707B1
公开(公告)日：2018-04-25
申请号：EP15716307.2
申请日：2015-03-27
发明人： HANLEY, Patrick S. , WHITEKER, Gregory T. , OBER, Matthias S. , KRUPER, William J. Jr. , KRASOVSKIY, Arkady L.
IPC分类号： C07B37/04 , C07C67/343 , C07C41/30 , C07C1/32 , C07C45/70 , C07C211/45 , C07C231/12 , C07C233/00 , C07D263/54 , C07C253/30 , C07D213/127 , C07D213/16
CPC分类号： C07C1/322 , C07B37/04 , C07C1/321 , C07C15/14 , C07C17/263 , C07C22/04 , C07C22/08 , C07C41/30 , C07C45/70 , C07C67/343 , C07C211/45 , C07C231/12 , C07C233/00 , C07C253/30 , C07C2531/22 , C07C2531/24 , C07C2531/28 , C07D213/127 , C07D213/16 , C07D263/54 , C07C233/65 , C07C255/50 , C07C43/205 , C07C49/784 , C07C69/76
摘要： In one aspect, there is provided a method of coupling a first aromatic compound having a fluorosulfonate substituent to a second aromatic compound having a boron-containing substituent. In another aspect, there is provided a method of coupling a first aromatic compound having a hydroxyl substituent to a second aromatic compound having a boron-containing substituent in a one-pot reaction.
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公开(公告)号：EP3204356A1
公开(公告)日：2017-08-16
申请号：EP15791810.3
申请日：2015-10-08
发明人： HANLEY, Patrick S. , OPPENHEIMER, Jossian , OBER, Matthias S. , KRUPER, William J. Jr. , KRASOVSKIY, Arkady L.
IPC分类号： C07D213/55 , C07C67/343 , C07C41/30 , C07C231/12 , C07C69/18 , C07C69/65 , C07C69/78 , C07C69/734 , C07C235/84 , C07C43/205
CPC分类号： C07C67/343 , C07C2/868 , C07C41/30 , C07C67/31 , C07C231/12 , C07C2531/20 , C07C2531/22 , C07C2531/24 , C07D213/55 , C07D317/60 , C07C69/734 , C07C69/65 , C07C69/618 , C07C69/76 , C07C15/52 , C07C15/50 , C07C43/215 , C07C233/65
摘要： The present disclosure describes a method of coupling a first compound to a second compound, the method comprising: providing the first compound having a fluorosulfonate substituent; providing the second compound comprising an alkene; and reacting the first compound and the second compound in a reaction mixture, the reaction mixture including a catalyst having at least one group 10 atom, the reaction mixture under conditions effective to couple the first compound to the second compound.
摘要翻译： 本公开描述了将第一化合物偶联至第二化合物的方法，所述方法包括：提供具有氟磺酸酯取代基的第一化合物; 提供包含烯烃的第二化合物; 以及使第一化合物和第二化合物在反应混合物中反应，所述反应混合物包含具有至少一个第10族原子的催化剂，反应混合物在有效将第一化合物偶联至第二化合物的条件下。
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7.发明公开METHOD FOR COUPLING A FIRST AROMATIC COMPOUND TO A SECOND AROMATIC COMPOUND 有权法求耦合与第二芳香族化合物的第一芳香族CONNECTION
公开(公告)号：EP3122707A1
公开(公告)日：2017-02-01
申请号：EP15716307.2
申请日：2015-03-27
发明人： HANLEY, Patrick S. , WHITEKER, Gregory T. , OBER, Matthias S. , KRUPER, Jr. , KRASOVSKIY, Arkady L.
IPC分类号： C07B37/04
CPC分类号： C07C1/322 , C07B37/04 , C07C1/321 , C07C15/14 , C07C17/263 , C07C22/04 , C07C22/08 , C07C41/30 , C07C45/70 , C07C67/343 , C07C211/45 , C07C231/12 , C07C233/00 , C07C253/30 , C07C2531/22 , C07C2531/24 , C07C2531/28 , C07D213/127 , C07D213/16 , C07D263/54 , C07C233/65 , C07C255/50 , C07C43/205 , C07C49/784 , C07C69/76
摘要： In one aspect, there is provided a method of coupling a first aromatic compound having a fluorosulfonate substituent to a second aromatic compound having a boron-containing substituent. In another aspect, there is provided a method of coupling a first aromatic compound having a hydroxyl substituent to a second aromatic compound having a boron-containing substituent in a one-pot reaction.
摘要翻译： 在一个方面，提供了一种具有一个取代基氟磺酸具有含硼取代基的第二芳族化合物的第一芳族化合物偶联的方法。 在另一个方面，提供了一种具有一个羟基取代基具有在一个单釜反应中的含硼取代基的第二芳族化合物的第一芳族化合物偶联的方法。
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