-
1.发明授权SPIRO COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION 失效螺环化合物作为抑制剂纤维蛋白原依赖性血小板聚集
公开(公告)号：EP0854869B1
公开(公告)日：2004-08-25
申请号：EP96936093.2
申请日：1996-09-27
发明人： FISHER, Matthew, J. , JAKUBOWSKI, Joseph, A. , MASTERS, John, J. , MULLANEY, Jeffrey, T. , PAAL, Michael , RÜHTER, Gerd , RUTERBORIES, Kenneth, J. , SCARBOROUGH, Robert, M. , SCHOTTEN, Theo , STENZEL, Wolfgang
IPC分类号： C07D221/20 , A61K31/435 , C07D498/10 , C07D471/10 , C07D401/06 , C07D263/52 , A61K31/42
CPC分类号： C07D221/20 , A61K31/423 , A61K31/437 , C07D263/52 , C07D471/10
-
2.发明公开SPIRO COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION 失效螺环化合物作为抑制剂纤维蛋白原依赖性血小板聚集
公开(公告)号：EP0854869A1
公开(公告)日：1998-07-29
申请号：EP96936093.0
申请日：1996-09-27
发明人： FISHER, Matthew, J. , JAKUBOWSKI, Joseph, A. , MASTERS, John, J. , MULLANEY, Jeffrey, T. , PAAL, Michael , RÜHTER, Gerd , RUTERBORIES, Kenneth, J. , SCARBOROUGH, Robert, M. , SCHOTTEN, Theo , STENZEL, Wolfgang
CPC分类号： C07D221/20 , A61K31/423 , A61K31/437 , C07D263/52 , C07D471/10
摘要： This invention relates to certain spirocyclic compounds substituted with both basic and acidic functionality, which are useful in inhibition of platelet aggregation.
-
公开(公告)号：EP1019047B1
公开(公告)日：2003-11-05
申请号：EP98920057.1
申请日：1998-04-30
发明人： BASTIAN, Jolie, A. , CHIRGADZE, Nickolay Y. , DENNEY, Michael, L. , FISHER, Matthew, J. , FOGLESONG, Robert, J. , HARPER, Richard, W. , JOHNSON, Mary, G. , KLIMKOWSKI, Valentine, J. , LIN, Ho-Shen , LYNCH, Michael, P. , MCCOWAN, Jefferson, R. , MILLER, Shawn, C. , MULLANEY, Jeffrey, T. , RICHETT, Michael, E. , SALL, Daniel, J. , SMITH, Gerald, F. , TAKEUCHI, Kumiko , TINSLEY, Jennifer, M. , WILEY, Michael, R. , ZHANG, Minsheng
IPC分类号： A61K31/415 , A61K31/41 , C07D235/18 , A61P7/02
CPC分类号： C07D231/12 , A61K31/4184 , A61K31/4196 , A61K31/497 , C07D233/56 , C07D235/18 , C07D249/08 , C07D403/12
-
公开(公告)号：EP1019047A1
公开(公告)日：2000-07-19
申请号：EP98920057.1
申请日：1998-04-30
发明人： BASTIAN, Jolie, A. , CHIRGADZE, Nickolay Y. , DENNEY, Michael, L. , FISHER, Matthew, J. , FOGLESONG, Robert, J. , HARPER, Richard, W. , JOHNSON, Mary, G. , KLIMKOWSKI, Valentine, J. , LIN, Ho-Shen , LYNCH, Michael, P. , MCCOWAN, Jefferson, R. , MILLER, Shawn, C. , MULLANEY, Jeffrey, T. , RICHETT, Michael, E. , SALL, Daniel, J. , SMITH, Gerald, F. , TAKEUCHI, Kumiko , TINSLEY, Jennifer, M. , WILEY, Michael, R. , ZHANG, Minsheng
IPC分类号： A61K31/415 , A61K31/41
CPC分类号： C07D231/12 , A61K31/4184 , A61K31/4196 , A61K31/497 , C07D233/56 , C07D235/18 , C07D249/08 , C07D403/12
摘要： This application relates to novel compounds of formula (I), and their pharmaceutically acceptable salts, as defined herein, processes and intermediates for their preparation, pharmaceutical formulations comprising the novel compounds of formula (I), and the use of the compounds of formula (I) as thrombin inhibitors.
摘要翻译： 本申请涉及如本文所定义的新的式（I）化合物及其药学上可接受的盐，其制备方法和中间体，包含式（I）的新化合物的药物制剂，以及式 I）作为凝血酶抑制剂。
-
-
-
搜索结果
4 条记录 (耗时 0.014 秒)
