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11 条记录 (耗时 0.016 秒)

    SENSOR ASSEMBLY
    1.
    发明公开
    SENSOR ASSEMBLY 审中-公开

    公开(公告)号：EP4016068A1

    公开(公告)日：2022-06-22

    申请号：EP20215881.2

    申请日：2020-12-21

    申请人： F. Hoffmann-La Roche AG ,  Roche Diagnostics GmbH

    发明人： BURKHARDT, Wolfgang ,  RUF, Miriam ,  BOEHM, Christoph ,  OCVIRK, Gregor

    IPC分类号： G01N27/27 ,  G01N27/327 ,  G01N27/333 ,  G01N33/49 ,  B01L3/00

    摘要： The present disclosure refers to a sensor assembly (1, 1', 1") for an IVD analyzer, the sensor assembly (1, 1', 1") comprising two opposite substrates (10A, 10B, 20A, 20B, 30A, 30B) with at least one fluidic conduit (2, 3, 4) for receiving a sample. The electrodes of different types of electrochemical sensors are arranged on the two opposite substrates (10A, 10B, 20A, 20B, 30A, 30B) facing the at least one fluidic conduit (2, 3, 4) for coming in contact with the sample and determining sample parameters, wherein the counter electrodes (11C, 11D) and the reference electrodes (11B, 12B) are formed on one substrate (10A, 10B, 20A, 20B, 30A, 30B) and the working electrodes (11A, 12A, 12A') are formed on the opposite substrate (10A, 10B, 20A, 20B, 30A, 30B). This achieves optimal sensor-working conditions in terms of a homogeneous and symmetrical electric field density and enables a sensor assembly with simpler geometry and smaller size.

    FLUIDISCHE STRUKTUR UND VERFAHREN ZUM ERZEUGEN EINER FLUIDISCHEN STRUKTUR
    5.
    发明公开
    FLUIDISCHE STRUKTUR UND VERFAHREN ZUM ERZEUGEN EINER FLUIDISCHEN STRUKTUR 审中-公开
    流结构和方法，用于产生流体结构

    公开(公告)号：EP1833607A1

    公开(公告)日：2007-09-19

    申请号：EP05846530.3

    申请日：2005-12-22

    申请人： Roche Diagnostics GmbH ,  F. HOFFMANN-LA ROCHE AG

    发明人： OCVIRK, Gregor ,  HOCHMUTH, Gernot ,  FIEDLER, Wolfgang

    IPC分类号： B01L3/00

    CPC分类号： B29C65/54 ,  B01L3/502707 ,  B01L3/502715 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/12 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0887 ,  B29C65/483 ,  B29C65/4845 ,  B29C66/1122 ,  B29C66/1222 ,  B29C66/1224 ,  B29C66/522 ,  B29C66/534 ,  B29C66/71 ,  B29L2031/756 ,  F16L37/025 ,  Y10T156/1043 ,  B29K2023/38 ,  B29K2069/00 ,  B29K2083/00

    摘要： In particular in medical diagnostics, analysis or microreactor technology it is frequently necessary to couple fluid conductors (114) to particular, fluid structures, for example, a fluid chip (112). A method for production of a fluid structure (110) is hence disclosed, in which, firstly, an opening (122) accessible from the exterior, is introduced in at least one base substrate (120) of the fluid structure (110). Then, at least one section (130) of a fluid conductor (114), in particular, a tube or hose is at least partly introduced into said at least one opening (122). Furthermore, at least one hardening fluid sealing material (132) is introduced into the at least one opening (122). The at least one fluid sealing material (132) is then partly or completely hardened, which can occur by the effect of electromagnetic radiation, or by a thermal effect. At least one connector channel (136) between at least one inner lumen (118) of the at least one fluid conductor (114) and at least one fluid channel (128) of the fluid structure (110) is generated. On generation of said connector channel (136), mechanical methods, for example, drilling or milling, or also laser ablation methods, laser drilling methods, wet-chemical etching or dry etching and other methods may be used. Said method may be particularly reproducibly carried out, such as to be suitable for a serial production of fluid structures (110). Fluid structures (110), produced by said method have low dead volumes for the fluid connection, whereby said dead volumes are reproducibly produced. Also, several fluid channels (128) may be simultaneously connected to the inner lumen (118) of a fluid conductor (114) and a secure mechanically stable connection between the fluid conductor (114) and a fluid chip (112) may be produced.

    SENSOR DEVICE AND METHOD OF ITS USE
    7.
    发明公开
    SENSOR DEVICE AND METHOD OF ITS USE 审中-公开

    公开(公告)号：EP4016069A1

    公开(公告)日：2022-06-22

    申请号：EP20215882.0

    申请日：2020-12-21

    申请人： F. Hoffmann-La Roche AG ,  Roche Diagnostics GmbH

    发明人： BOEHM, Christoph ,  BURKHARDT, Wolfgang ,  LUTZ, Sascha ,  OCVIRK, Gregor ,  RUF, Miriam ,  KONTSCHIEDER, Heinz

    IPC分类号： G01N27/27 ,  G01N27/327 ,  G01N27/333 ,  G01N33/49 ,  B01L3/00

    摘要： The present disclosure refers to a sensor device (1, 1'), a method of operating the sensor device (1, 1') and an IVD analyzer (100) for receiving the sensor device (1, 1') for determining chemical and/or physical characteristics of a fluid. The sensor device (1, 1') comprises at least two fluidic conduits (2, 2', 3) for repeatedly receiving fluids, each fluidic conduit (2, 2', 3) comprising at least one sensory element (11A, 11B, 12A, 12B, 13, 14, 15) arranged such as to come in contact with a fluid in the respective fluidic conduit (2, 2', 3). In particular, the fluidic conduits (2, 2', 3) comprise different sensory elements, respectively, wherein the sensory elements are separated in the respective fluidic conduits according to compatibility or susceptibility to deterioration or operating temperature. Alternately, the fluidic conduits (2, 2', 3) comprise at least in part the same sensory elements, wherein the sensor device (1, 1') is operated in a primary operating mode and in response to a trigger event, switches to an extended operating mode.