ADHESIVE PREPARATION
    2.
    发明公开
    ADHESIVE PREPARATION 审中-公开
    KLEBSTOFFPRÄPARAT

    公开(公告)号:EP2047845A1

    公开(公告)日:2009-04-15

    申请号:EP07791748.2

    申请日:2007-08-01

    摘要: An adhesive preparation comprising a stretchable support and an adhesive layer laminated on at least one side of the support, wherein
    the stretchable support comprises a interlock woven fabric subjected to crimping processing,
    the adhesive layer contains 10% by mass or more of methyl salicylate with respect to the total mass of the layer,
    the whole adhesive preparation has moisture permeability of 1 to 350 g/m 2 ·24 hr measured at a temperature of 40°C and a relative humidity of 90%, and
    the methyl salicylate has a plasma AUC 0-24 ranging from 3.0 to 60.0 ng·hr/mL in terms of a mean ± standard deviation, and salicylic acid as a metabolite of the methyl salicylate has a plasma AUC 0-24 ranging from 5000 to 13000 ng·hr/mL in terms of a mean ± standard deviation, when the adhesive preparation is applied to a human skin for 8 hours such that an application amount of the adhesive layer applied is 50 to 300 g/m 2 and a contact area is 280 cm 2 .

    摘要翻译: 一种粘合剂制剂,包括层压在所述载体的至少一侧上的可拉伸载体和粘合剂层,其中所述可拉伸载体包括进行压接加工的互锁织物,所述粘合剂层包含10质量%以上的水杨酸甲酯, 对于该层的总质量,整个粘合剂制剂在40℃和相对湿度为90%的温度下测得的透湿度为1至350g / m 2·24小时,水杨酸甲酯具有血浆AUC 0-24范围为3.0〜60.0ng·hr / mL,平均±标准偏差,作为水杨酸甲酯代谢物的水杨酸的血浆AUC 0-24为5000〜13000ng·hr / mL, 当将粘合剂制剂施用于人类皮肤8小时,使得施加的粘合剂层的涂布量为50-300g / m 2,接触面积为280cm 2时,平均±标准偏差的术语。

    MEDICATED PATCH
    9.
    发明公开
    MEDICATED PATCH 有权
    麻省理工学院

    公开(公告)号:EP2143445A1

    公开(公告)日:2010-01-13

    申请号:EP08751979.9

    申请日:2008-04-23

    摘要: A conventional medicated patch containing an anti-inflammatory agent causes a dermatitis or the like on rare occasion by excess irradiation with light. For overcoming the problem, a medicated patch is provided, which comprises an anti-inflammatory agent, BM-DBM as an ultraviolet absorber, and hexyl laurate as an agent for accelerating the migration of the ultraviolet absorber into the skin in an adhesive base material thereof.

    摘要翻译: 含有抗炎剂的常规药物贴剂在极少的情况下通过过度的光照射引起皮炎等。 为了克服上述问题,提供了一种药物贴剂,其包含抗炎剂,作为紫外线吸收剂的BM-DBM和月桂酸己酯作为促进紫外线吸收剂在其粘合剂基材中向皮肤迁移的试剂 。

    ADHESIVE AND ADHESIVE PATCH
    10.
    发明公开
    ADHESIVE AND ADHESIVE PATCH 有权
    KLEBSTOFF UND KLEBEPFLASTER

    公开(公告)号:EP1864655A1

    公开(公告)日:2007-12-12

    申请号:EP06728832.4

    申请日:2006-03-09

    摘要: An adhesive comprising a base with tackiness, an oil and ketoprofen, wherein the adhesive contains no L-menthol, the base is composed at least of a tacky composition comprising an elastomer and a tackifier and/or a tacky polymer containing an unsaturated monomer with a total of 5 or more carbon atoms as the monomer unit, the oil is an oil that is compatible with the tacky composition and the tacky polymer, and the oil content is 150-175 parts by weight with respect to 100 parts by weight as the total of the tacky composition and the tacky polymer.

    摘要翻译: 一种粘合剂,其包含具有粘性的基料,油和酮洛芬,其中所述粘合剂不含L-薄荷醇,所述基材至少由粘合组合物组成,所述粘性组合物包含弹性体和增粘剂和/或含有不饱和单体的粘性聚合物, 总共有5个以上的碳原子作为单体单元,油是与粘性组合物和粘性聚合物相容的油,相对于100重量份,油的含量相对于100重量份为150-175重量份 的粘性组合物和粘性聚合物。