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22 条记录 (耗时 0.014 秒)

    Use of pharmaceutical compositions comprising cyclohexane derivatives in the treatment or prevention of peptic ulcers
    6.
    发明公开
    Use of pharmaceutical compositions comprising cyclohexane derivatives in the treatment or prevention of peptic ulcers 失效
    使用在胃溃疡的治疗或预防的药物组合物的环己烷衍生物。

    公开(公告)号：EP0282643A2

    公开(公告)日：1988-09-21

    申请号：EP87117155.9

    申请日：1987-11-20

    申请人： THE GREEN CROSS CORPORATION

    发明人： Fukaya, Chikara ,  Yasuda, Hitoshi ,  Akira, Toshiaki ,  Iwai, Masakazu ,  Okano, Kanemichi ,  Yokoyama, Kazumasa

    IPC分类号： A61K31/045 ,  A61K31/075 ,  A61K31/12 ,  A61K31/215 ,  A61K31/22 ,  A61K31/70

    CPC分类号： A61K31/7004 ,  A61K31/045 ,  A61K31/075 ,  A61K31/12 ,  A61K31/215 ,  A61K31/22 ,  A61K31/70 ,  C07C47/192 ,  C07C47/198 ,  C07C49/11 ,  C07C49/172 ,  C07C49/175 ,  C07C49/497 ,  C07C49/517 ,  Y10S514/927

    摘要： A therapeutic and prophylactic agent for peptic ulcers comprising as an effective ingredient a cyclohexane derivative represented by general formula (I):
    wherein A represents a group shown by formula, >CH₂,
    X represents ethynylene, vinylene or ethylene, Y represents oxo or a hydroxy group;
    R¹, R³, R⁴ and R⁵ each represents a hydrogen atom or substituted or un­substituted alkyl; R² represents a hydrogen atom or substituted or unsubstituted alkyl or a group shown by -OR⁸; R⁶ represents a hydrogen atom, oxo or a group shown by -OR⁸; R⁷ represents a hydrogen atom or a group shown by -OR⁸, and R⁸ represents a hydrogen atom or an organic residue, and a pharmaceutically acceptable additive.
    Such derivatives are also provided for use as a medicament, particularly for the treatment or prevention of peptic ulcers.
    The use of such derivatives for the manufacture of a medicament having therapeutic and preventative value is also provided.

    摘要翻译： 用于治疗消化性溃疡，其包含如上有效成分的治疗和预防剂的环己烷衍生物由通式（I）表示： worin甲darstellt由式所示的基团，> CH 2， X darstellt亚乙炔基，亚乙烯基或亚乙基， ÿdarstellt氧代或羟基; [R <1>，R <3>，R <4>和R <5>每个darstellt氢原子或substituiertem奥德unsubstituiertem烷基; [R <2>代表氢原子或substituiertem奥德unsubstituiertem烷基或-O-R <8>所示的基团; [R <6>代表氢原子，氧代基或-O-R <8>所示的基团; [R <7> darstellt氢原子或由-OR <8>所示的基团，并且R <8> darstellt氢原子或添加剂的有机残基，和药学上可接受的。 因此，提供用作药物的搜索衍生物，特别是用于治疗消化性溃疡的治疗或预防。 利用衍生的搜索具有治疗和预防价值的药物中的用途因此，提供。

    Perfusate for preserving organ to be transplanted and preserving method
    10.
    发明公开
    Perfusate for preserving organ to be transplanted and preserving method 失效
    Perfusatflüssigkeitzur Aufbewahrung eines zu transplantierenden Organs und Aufbewahrungsverfahren。

    公开(公告)号：EP0033402A1

    公开(公告)日：1981-08-12

    申请号：EP80300245.0

    申请日：1980-01-25

    申请人： The Green Cross Corporation

    发明人： Yokoyama, Kazumasa ,  Iwai, Masakazu ,  Okamoto, Hiroyuki ,  Yamada, Noboru

    IPC分类号： A01N1/00

    CPC分类号： A01N1/02 ,  A01N1/0226

    摘要： An organ to be transplanted, such as a kidney, can effectively be preserved for an increased period of time by perfusion using a perfusate which is made of a Ringer's solution modified by increasing its potassium ion content to 8-20 meq/liter with a stably emulsified perfluorocarbon compound and dissolved albumin. A preferred concentration of the perfluorocarbon compound, for example perfluorodecalin, is 7.5 to 12.5%(W/V) and that of albumin is 1-8%(W/V) based on the perfusate.

    摘要翻译： 通过使用由通过将稳定地将其钾离子含量增加至8-20meq /升而修饰的林格氏溶液的灌注液灌注而可以有效地保持移植器官，例如肾脏，以增加一段时间 乳化全氟化碳化合物和溶解白蛋白。 全氟化碳化合物（例如全氟萘烷）的优选浓度为7.5至12.5％（W / V），白蛋白的优选浓度为基于灌洗液的1-8％（W / V）。