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公开(公告)号：EP3421492A1
公开(公告)日：2019-01-02
申请号：EP18173405.4
申请日：2006-04-28
发明人： CHEN, Yan , GARDNER, Debra , KNIGHT, David M. , LARK, Michael W. , LIANG, Bailin , SHEALY, David J. , SONG, Xiao-Yu, R. , STOJANOVIC-SUSULIC, Vedrana , SWEET, Raymond W. , TAM, Susan H. , WU, Sheng-Jiun , YANG, Jing , MARQUIS, David Matthew , SMITH, Eric Michael , VASSEROT, Alain Philippe
摘要： An anti-IL-6 antibody, including isolated nucleic acids that encode at least one anti-IL-6 antibody, vectors, host cells, transgenic animals or plants, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices.
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公开(公告)号：EP3578567A1
公开(公告)日：2019-12-11
申请号：EP19173615.6
申请日：2012-12-19
发明人： ALDERFER, Christopher , JANECKI, Dariusz , LIU, Xuesong , MURDOCK, Melissa , WU, Sheng-Jiun , MERCKEN, Marc , VANDERMEEREN, Marc , MALIA, Thomas
摘要： The present invention relates to anti-PHF tau antibodies and methods of making and using them.
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公开(公告)号：EP3405493A1
公开(公告)日：2018-11-28
申请号：EP17702264.7
申请日：2017-01-19
发明人： ANDERSON, Glenn Mark , ATTAR, Ricardo , BALDWIN, Eric T. , CARDOSO, Rosa M.F. , GAUDET, Francois , HARMAN, Benjamin , LI, Yingzhe , LUO, Jinquan , MCDAID, Ronan , NEMETH-SEAY, Jennifer F. , POMERANTZ, Steven C. , TEPLYAKOV, Alexey , TAM, Susan H. , WU, Sheng-Jiun
IPC分类号： C07K16/28 , A61P35/00 , A61K39/395
CPC分类号： C07K16/28 , A61K2039/505 , C07K16/2803 , C07K16/2809 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/565 , C07K2317/73 , C07K2317/92
摘要： Provided herein are isolated antibodies that immunospecifically bind to ROR1, bispecific antibodies comprising an antigen-binding site that immunospecifically binds to ROR1 and an antigen-binding site that immunospecifically binds to CD3, and methods of using the same.
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公开(公告)号：EP3370768A1
公开(公告)日：2018-09-12
申请号：EP16862773.5
申请日：2016-11-01
发明人： VERONA, Raluca , POWERS, Gordon , SABINS, Nina Chi , DEANGELIS, Nikki A. , SANTULLI-MAROTTO, Sandra , WIEHAGEN, Karla R. , WU, Sheng-Jiun , FERRANTE, Catherine , UBANI, Enrique-Zudaire
IPC分类号： A61K39/395 , A61K39/00
CPC分类号： C07K16/2803 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/1063 , C07K16/2818 , C07K16/4258 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/71 , C07K2317/75 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：EP3802607A2
公开(公告)日：2021-04-14
申请号：EP19737217.0
申请日：2019-05-21
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公开(公告)号：EP3390453A2
公开(公告)日：2018-10-24
申请号：EP16829362.9
申请日：2016-12-16
发明人： MARTINEZ, Christian , CHEN, Qiang , SWIECKI, Melissa , KUHN, Robert , ZHOU, Hong , DUFFY, Karen , BECART, Stephane , HUANG, Chichi , LIN-SCHMIDT, Xiefan , WU, Sheng-Jiun , LUO, Jinquan , OBMOLOVA, Galina , ERNST, Robin
IPC分类号： C07K16/28
CPC分类号： C07K16/2833 , C07K2317/21 , C07K2317/56 , C07K2317/92
摘要： The present invention relates antibodies or antigen-binding fragments thereof specifically binding HLA-DR, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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公开(公告)号：EP2844292A2
公开(公告)日：2015-03-11
申请号：EP13785158.0
申请日：2013-04-29
发明人： DUFFY, Karen , HEALY, Catherine , LAMB, Roberta , MALAVIYA, Ravi , PRATTA, Michael , FURSOV, Natalie , LUO, Jinquan , NASO, Michael , TORNETTA, Mark , WHEELER, John , WU, Sheng-Jiun , HALL, LeRoy
IPC分类号： A61K39/395 , C07K16/24
CPC分类号： C07K16/2866 , A61K38/012 , A61K39/3955 , A61K2039/505 , C07K16/44 , C07K2317/21 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
摘要翻译： 本发明涉及ST2L拮抗剂，编码拮抗剂或其片段的多核苷酸，以及制备和使用上述物质的方法。
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公开(公告)号：EP3597219A1
公开(公告)日：2020-01-22
申请号：EP19192657.5
申请日：2013-04-29
发明人： DUFFY, Karen , HEALY, Catherine , LAMB, Roberta , MALAVIYA, Ravi , PRATTA, Michael , FURSOV, Natalie , LUO, Jinquan , NASO, Michael , TORNETTA, Mark , WHEELER, John , WU, Sheng-Jiun , HALL, LeRoy
摘要： The present invention relates to ST2L antagonists, polynucleotides encoding the antagonists or fragments thereof, and methods of making and using the foregoing.
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公开(公告)号：EP2794654B1
公开(公告)日：2019-05-22
申请号：EP12859920.6
申请日：2012-12-19
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公开(公告)号：EP3370769A1
公开(公告)日：2018-09-12
申请号：EP16862775.0
申请日：2016-11-01
发明人： VERONA, Raluca , POWERS, Gordon , SABINS,Nina Chi , DEANGELIS, Nikki A. , SANTULLI-MAROTTO, Sandra , WIEHAGEN, Karla R. , WU, Sheng-Jiun , FERRANTE, Catherine , UBANI, Enrique Zudaire
IPC分类号： A61K39/395 , C12N15/13 , C07K16/18
CPC分类号： C07K16/2803 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K16/1063 , C07K16/2818 , C07K16/4258 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/55 , C07K2317/565 , C07K2317/71 , C07K2317/75 , C07K2317/76 , C07K2317/92
摘要： The present invention relates to antibodies specifically binding PD-1, TIM-3 or PD-1 and TIM-3, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
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