公开(公告)号：EP2894185A1

公开(公告)日：2015-07-15

申请号：EP13835971.6

申请日：2013-09-06

Applicant: Japan Science and Technology Agency

Inventor： HARIYAMA Takahiko ,  TAKAKU Yasuharu ,  SUZUKI Hiroshi ,  SHIMOMURA Masatsugu ,  ISHII Daisuke ,  OHTA Isao ,  MURANAKA Yoshinori

IPC: C08G83/00 ,  C09D4/00 ,  C09D201/00

CPC classification number: B01D71/38 ,  B01D67/009 ,  B01D69/02 ,  B01D69/127 ,  B01D2323/30 ,  B01D2325/36 ,  C09D4/00 ,  C09D4/06

Abstract: Provided is a technique for fabricating a novel thin membrane with a starting material such as a biocompatible compound that is not easily processible into a membrane, particularly a technique for fabricating a novel thin membrane of a composition that is gradually polymerized from a membrane surface into the membrane in the cross sectional direction of the membrane, and having, for example, different structures on the front and back of the membrane. The technique includes the steps of preparing a solution of a starting material compound; forming a thin membrane of the solution on a base material surface; and forming the organic polymer thin membrane through a polymerization reaction caused by irradiating the exposed surface of the thin membrane with a plasma or an electron beam.

Abstract translation: 本发明提供一种用难以加工成膜的生物体系相容性化合物等原材料制造新型薄膜的技术，特别是涉及从膜表面逐渐聚合成膜的组合物的新型薄膜技术 在膜的横截面方向上具有膜，并且在膜的正面和背面上具有例如不同的结构。 该技术包括制备原料化合物溶液的步骤; 在基材表面上形成溶液的薄膜; 以及通过用等离子体或电子束照射薄膜的暴露表面而引起的聚合反应形成有机聚合物薄膜。

公开(公告)号：EP2894185B1

公开(公告)日：2017-11-29

申请号：EP13835971.6

申请日：2013-09-06

Applicant: Japan Science and Technology Agency

Inventor： HARIYAMA Takahiko ,  TAKAKU Yasuharu ,  SUZUKI Hiroshi ,  SHIMOMURA Masatsugu ,  ISHII Daisuke ,  OHTA Isao ,  MURANAKA Yoshinori

IPC: C08G83/00 ,  C09D4/00 ,  C09D201/00 ,  C09D4/06

CPC classification number: B01D71/38 ,  B01D67/009 ,  B01D69/02 ,  B01D69/127 ,  B01D2323/30 ,  B01D2325/36 ,  C09D4/00 ,  C09D4/06

Abstract: Provided is a technique for fabricating a novel thin membrane with a starting material such as a biocompatible compound that is not easily processible into a membrane, particularly a technique for fabricating a novel thin membrane of a composition that is gradually polymerized from a membrane surface into the membrane in the cross sectional direction of the membrane, and having, for example, different structures on the front and back of the membrane. The technique includes the steps of preparing a solution of a starting material compound; forming a thin membrane of the solution on a base material surface; and forming the organic polymer thin membrane through a polymerization reaction caused by irradiating the exposed surface of the thin membrane with a plasma or an electron beam.

公开(公告)号：EP3101407A1

公开(公告)日：2016-12-07

申请号：EP15742637.0

申请日：2015-01-28

Applicant: Japan Science and Technology Agency

Inventor： HARIYAMA Takahiko ,  TAKAKU Yasuharu ,  SUZUKI Hiroshi ,  HIRAKAWA Satoshi ,  KAWASAKI Hideaki ,  SHIMOMURA Masatsugu ,  ISHII Daisuke ,  OHTA Isao ,  MURANAKA Yoshinori

IPC: G01N1/28 ,  G01N23/00 ,  G01N33/574 ,  H01J37/20

CPC classification number: H01J37/20 ,  G01N33/4833 ,  G01N33/5011 ,  G01N2223/612 ,  G01N2800/7028 ,  H01J37/22 ,  H01J2237/2002 ,  H01J2237/2007

Abstract: Provided are a protective agent for electron microscopic observation in a vacuum which can protect a biological sample in a water-containing state, such as a mammal, a plant tissue or a cultured cell, and a single cell in the living state without deforming it even in a vacuum, a kit using the same, methods for observation, diagnosis, evaluation, and quantification of a sample by an electron microscope, and a sample stage to be used for the observation. The protective agent for electron microscopic observation of the present invention contains a survival environment imparting component, a saccharide, and an electrolyte.

Abstract translation: 提供了用于在真空中其可以在含水状态保护的生物样品的电子显微观察的保护剂，检查为哺乳动物，植物组织或培养的细胞，和单细胞在活状态甚至没有使其变形 在真空中，将用于观察的试剂盒使用用于监视，诊断，评估和定量的样品的相同，方法通过在电子显微镜，和样品阶段。 对于本发明的电子显微镜观察的保护剂中含有的生存环境赋予成分，糖，以及电解质。