公开(公告)号：EP1440688A4

公开(公告)日：2005-11-30

申请号：EP02802360

申请日：2002-10-11

申请人： KANEKA CORP

发明人： MAE TATSUMASA ,  TSUKAGAWA MISUZU ,  KITAHARA MIKIO ,  NAKAGAWA KAKU ,  KITAMURA SHIRO ,  UEDA YASUYOSHI ,  KURODA MINPEI ,  MIMAKI YOSHIHIRO ,  SASHIDA YUTAKA

IPC分类号： A23K1/16 ,  A23K1/18 ,  A23L1/30 ,  A61K31/12 ,  A61K31/353 ,  A61K31/366 ,  A61K31/37 ,  A61K36/00 ,  A61K36/484 ,  A61P3/04 ,  A61P3/06 ,  A61P3/10 ,  A61P9/10 ,  A61P9/12 ,  A61P37/02 ,  A61P43/00 ,  C07D311/06 ,  C07D311/18 ,  C07D311/30 ,  C07D311/36 ,  C07D311/38 ,  C07D311/58 ,  C07D493/04 ,  A61K35/78 ,  A61P29/00 ,  A61P35/00

CPC分类号： C07D311/06 ,  A23K20/111 ,  A23K20/121 ,  A23K50/00 ,  A23K50/40 ,  A23L33/10 ,  A23L33/105 ,  A61K31/12 ,  A61K31/353 ,  A61K31/37 ,  A61K36/484 ,  A61K2300/00

摘要： The present invention easily and efficiently provides a peroxisome proliferator-activated receptor ligand, and a composition for amelioration of insulin resistance or for prevention and/or amelioration of the insulin resistance syndrome containing the same, as an active ingredient. The present invention relates to a peroxisome proliferator-activated receptor ligand which comprises a prenylflavonoid, a chalcone derivative exclusive of prenylflavonoids, a flavonol derivative exclusive of prenylflavonoids, and a salt, a glycoside and/or an esterified substance thereof acceptable as a pharmaceutical preparation or a food or a beverage; a composition containing the above ligand; a plant-derived extract containing the above ligand; and a process for producing the above extract.

公开(公告)号：EP1350516A4

公开(公告)日：2004-05-19

申请号：EP01270339

申请日：2001-12-12

申请人： KANEKA CORP

发明人： MAE TATSUMASA ,  TSUKAGAWA MISUZU ,  KISHIDA HIDEYUKI ,  KITANO MITSUAKI ,  KITAHARA MIKIO ,  NAKAGAWA KAKU

IPC分类号： A21D2/36 ,  A23K1/16 ,  A23K1/18 ,  A23L1/24 ,  A23L1/30 ,  A23L1/302 ,  A23L1/304 ,  A23L1/305 ,  A61K8/97 ,  A61K33/06 ,  A61K36/00 ,  A61K36/48 ,  A61K36/54 ,  A61K36/61 ,  A61K36/9066 ,  A61P3/06 ,  A61P3/10 ,  A61P9/12 ,  A61Q19/06 ,  A61K35/78

CPC分类号： A61Q19/06 ,  A21D2/36 ,  A23K20/10 ,  A23K50/40 ,  A23L27/60 ,  A23L33/10 ,  A23L33/105 ,  A23L33/15 ,  A23L33/16 ,  A23L33/175 ,  A61K8/97 ,  A61K36/48 ,  A61K36/54 ,  A61K36/61 ,  A61K36/9066 ,  Y10S514/909 ,  A61K2300/00

摘要： Compositions for preventing or ameliorating multiple risk factor syndromes such as visceral fat-type obesity, diabetes, hyperlipemia and hypertension which contain at least one member selected from the group consisting of hydrophobic licorice root extract, turmeric extract, clove extract and cinnamon extract.

摘要翻译： 本发明的目的的组合物用于预防或改善多重危险因子综合征涉及内脏脂肪型肥胖，糖尿病，高脂血症和高血压，其包含选自下组甘草疏水提取物，姜黄提取物，中的至少一个构件 丁香提取物，和肉桂萃取物。

公开(公告)号：EP1491204A4

公开(公告)日：2005-09-14

申请号：EP03745912

申请日：2003-04-04

申请人： KANEKA CORP

发明人： IKEHARA TOSHINORI ,  KITAHARA MIKIO

IPC分类号： A23D9/00 ,  A23L1/221 ,  A23L1/30 ,  A61K36/484 ,  A61P1/06 ,  A61P11/10 ,  A61P25/04 ,  A61K35/78 ,  A61K47/14

CPC分类号： A61K36/484 ,  A23L27/11 ,  A23L33/105 ,  A23L33/12 ,  A61K2300/00

摘要： A fat solvent containing 10% by weight or more of a specific fat-soluble polyhydric alcohol fatty acid ester, in particular, a glycerol fatty acid ester is used as a solvent for extracting hydrophobic components of glycyrrhiza. Thus, the hydrophobic components of glycyrrhiza having excellent effects as foods and drinks such as health foods, foods with health claims (foods for specified health uses, foods with nutrient function claims), medicines, etc. can be produced at a reduced cost and the thus obtained compositions have elevated stability and improved handling properties.

公开(公告)号：EP0995745A4

公开(公告)日：2002-11-06

申请号：EP98929672

申请日：1998-06-25

申请人： KANEKA CORP

发明人： YOKOTA SHIN-ICHI ,  YAMAMOTO KOZO ,  MORIKAWA SOUICHI ,  FUSE YOSHIHIDE ,  KITAHARA MIKIO

IPC分类号： C07D405/06 ,  A61K31/40 ,  A61K31/445

CPC分类号： C07D405/06

摘要： Remedies for diseases which function by regulating the expression of a protein induced by a heat shock factor (HSF). Specifically, HSF activity inhibitors or agents inhibiting the induction of the production of a protein regulated by HSF, wherein novel benzo-1,3-dioxole compounds represented by general formula (I) inhibit the transcription of a structural gene having a heat shock element sequence, which is a transcriptional regulatory factor, in a gene region participating in the transcription into RNA, thus inhibit the translation of this gene into a protein and, in its turn, suppress the induction of the production of the RNA, protein, etc. encoded by the gene; and remedies and preventives usable in thermotherapy for cancer and remedies and preventives for stress-induced diseases such as depression. Compounds represented by general formula (I): wherein X is -CH2- and R1 represents C¿1-2? alkyl, formyl or halogeno; or X is -(CH2)2- and R?1¿ represents C¿1-3? alkyl, formyl, acetyl, hydrogen or halogeno.