公开(公告)号：EP2173695A1

公开(公告)日：2010-04-14

申请号：EP08783184.8

申请日：2008-07-07

申请人： Kanata Chemical Technologies Inc.

发明人： ABDUR-RASHID, Kamaluddin ,  GUO, Rongwei ,  CHEN, Xuanhua ,  JIA, Wenli

IPC分类号： C07C29/145 ,  B01J31/24 ,  B01J31/28 ,  C07C35/08

CPC分类号： B01J31/189 ,  B01J2231/643 ,  B01J2531/0238 ,  B01J2531/821 ,  C07B2200/09 ,  C07C29/145 ,  C07C2601/14 ,  C07C35/08

摘要： The present disclosure relates to a method for the stereoselective production of cis-4-tertbutylcyclohexanol comprising contacting 4-tert-butylcyclohexanone with hydrogen gas, a catalyst comprising a ruthenium-aminophosphine complex and a base, wherein the complex is of the formula RuX2 (PNH2)a(P2)b (I), wherein X is anionic ligand, (PNH2) represents an aminophosphine ligand of the formula (II) R1R2P-L- NH2 and (P2) represents a diphosphine ligand of the formula (III) R3R4P-L-PR5R6.

公开(公告)号：EP2167515A1

公开(公告)日：2010-03-31

申请号：EP08757212.9

申请日：2008-06-09

申请人： Kanata Chemical Technologies Inc.

发明人： ABDUR-RASHID, Kamaluddin ,  GUO, Rongwei ,  CHEN, Xuanhua ,  JIA, Wenli

IPC分类号： C07F9/50 ,  B01J31/24 ,  B01J37/00 ,  C07F9/6568 ,  C07F9/6571

CPC分类号： C07F9/65683 ,  B01J31/2409 ,  B01J31/2419 ,  B01J31/2495 ,  B01J2231/643 ,  B01J2531/821 ,  C07F9/5004 ,  C07F9/65719

摘要： The present application is directed to i) a method for synthesizing aminophosphine (P,N) and phosphine-aminophosphine (P,N,P) ligands, ii) the use of such ligands in the preparation of metal complexes as hydrogenation catalysts, and iii) aminophosphine (P,N) and phosphine-aminophosphine (P,N,P) ligands of various structures. In particular, the methods in i) involve reacting a protected tertiary amine of formula (I) with a metal phosphide of the formula Y-PR8R9 to afford an aminophosphine of formula (II), which can then be optionally further reacted with a phosphine of the formula (III) to afford the phosphine-aminophosphine of formula (IV).

公开(公告)号：EP2614069A1

公开(公告)日：2013-07-17

申请号：EP11822959.0

申请日：2011-09-09

申请人： Kanata Chemical Technologies Inc.

发明人： ABDUR-RASHID, Kamaluddin ,  JIA, Wenli ,  LU, Shuiming ,  GUO, Rongwei ,  CHEN, Xuanhua ,  AMOROSO, Dino

IPC分类号： C07F9/53 ,  B01J31/28 ,  C07C45/29 ,  C07C67/31 ,  C07D215/18 ,  C07D333/22

CPC分类号： C07F15/0093 ,  B01J31/1805 ,  B01J31/2226 ,  B01J31/2234 ,  B01J31/2409 ,  B01J2231/4211 ,  B01J2231/643 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/824 ,  C07B53/00 ,  C07B2200/07 ,  C07C29/145 ,  C07C67/31 ,  C07D333/22 ,  C07F9/4021 ,  C07F9/4025 ,  C07F9/42 ,  C07F9/46 ,  C07F9/5027 ,  C07F9/5325 ,  C07F9/5329 ,  C07F15/0053 ,  C07F15/0066 ,  C07C69/675 ,  C07C33/46 ,  C07C33/20 ,  C07C33/22

摘要： The present disclosure relates to biaryl diphosphine ligands of the formula (B), processes for the production of the ligands and the use of the ligands in metal catalysts for asymmetric synthesis. The disclosure also relates to intermediates used for the production of the biaryl diphosphine ligand. (Formula (B))

公开(公告)号：EP2215101A1

公开(公告)日：2010-08-11

申请号：EP08843506.0

申请日：2008-10-30

申请人： Kanata Chemical Technologies Inc.

发明人： ABDUR-RASHID, Kamaluddin ,  AMOROSO, Dino ,  GUO, Rongwei ,  CHEN, Xuanhua ,  SUI-SENG, Christine ,  TSANG, Chi-Wing ,  JIA, Wenli

IPC分类号： C07F15/00 ,  B01J23/74 ,  C07C211/65 ,  C07F15/02 ,  C07F9/50

CPC分类号： C07F15/0053 ,  B01J31/1805 ,  B01J31/181 ,  B01J31/189 ,  B01J31/2452 ,  B01J2231/4205 ,  B01J2231/4277 ,  B01J2231/641 ,  B01J2531/821 ,  B01J2531/825 ,  B01J2531/842 ,  C07C211/09 ,  C07C211/11 ,  C07C211/12 ,  C07C211/27 ,  C07C211/30 ,  C07C211/36 ,  C07C217/34 ,  C07C2601/14 ,  C07C2601/18 ,  C07F15/0046 ,  C07F15/025 ,  C07F17/02

摘要： The present disclosure includes catiomc complexes of iron, ruthenium, and osmium, and their use as catalysts in organic synthesis transformations including the hydrogenation of unsaturated compounds. The complexes are represented by the following formulae I, II, III, IV, and V, wherein M is Fe, Ru or Os, P is a monodentate ligand with a phosphorus donor atom, P2 is a bidentate neutral ligand with two phosphorus donor atoms, N2 is a bidentate neutral ligand with two nitrogen donor atoms, PN is a bidentate neutral ligand with phosphorus and nitrogen donor atoms, PNNP is a tetradentate neutral ligand bonded to M via two phosphorus and two nitrogen atoms, X is any anionic ligand, LB is any neutral Lewis base, Y is any non-coordmatmg anion, n is 0, 1, or 2, m is 1 or 2, q is 0 or 1, r is 1 or 2 and q + r = 2.

公开(公告)号：EP2158154A1

公开(公告)日：2010-03-03

申请号：EP08748325.1

申请日：2008-05-16

申请人： Kanata Chemical Technologies Inc.

发明人： ABDUR-RASHID, Kamaluddin ,  GRAHAM, Todd ,  TSANG, Chi-Wing ,  CHEN, Xuanhua ,  GUO, Rongwei ,  JIA, Wenli ,  AMOROSO, Dino ,  SUI-SENG, Christine

IPC分类号： C01B3/02 ,  B01J23/02 ,  B01J23/10 ,  B01J23/38 ,  B01J23/70 ,  C01B3/26

CPC分类号： C01B3/065 ,  B01J31/1805 ,  B01J31/1815 ,  B01J31/1875 ,  B01J31/189 ,  B01J31/2265 ,  B01J31/2273 ,  B01J31/24 ,  B01J2531/0238 ,  B01J2531/0255 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/827 ,  B01J2531/845 ,  B01J2531/847 ,  Y02E60/362 ,  Y02E60/364

摘要： The present disclosure relates to processes and methods of generating hydrogen via the hydrolysis or solvolyis of a compound of the formula (I), R1R2HNBHR3R4, using ligand-stabilized homogeneous metal catalysts.