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公开(公告)号：EP3640254A1
公开(公告)日：2020-04-22
申请号：EP19201582.4
申请日：2013-02-08
发明人： KJUS, Nini , FONNUM, Geir , BRANCHAUD, Bruce , YING, Lai-Qiang , MENCHEN, Steven , GREMYACHINSKIY, Dmitriy , KANG, Hee Chol
IPC分类号： C07F7/18 , C08F222/38 , C08F220/58
摘要： A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
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公开(公告)号：EP3317314B1
公开(公告)日：2020-01-08
申请号：EP16741201.4
申请日：2016-07-01
发明人： FONNUM, Geir , MENCHEN, Steven, M. , GOKMEN, Talha, M. , LUNDBERG, Pontus , THWAR, Prasanna Krishnan , LUI, Alfred , LU, Lily , HINZ, Wolfgang , HUSABOE, Lene , BREIVOLD, Elisabeth , MOLTEBERG, Astrid, Evenroed , LARSEN, Synne
IPC分类号： C08F220/58 , C08F8/12
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公开(公告)号：EP3702383A1
公开(公告)日：2020-09-02
申请号：EP20150423.0
申请日：2016-07-01
发明人： FONNUM, Geir , MENCHEN, Steven M. , GOKMEN, Talha M. , LUNDBERG, Pontus , THWAR, Prasanna Krishnan , LUI, Alfred , LU, Lily , HINZ, Wolfgang , HUSABOE, Lene , BREIVOLD, Elisabeth , MOLTEBERG, Astrid Evenroed , LARSEN, Synne
IPC分类号： C08F220/58 , C08F8/12
摘要： A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.
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公开(公告)号：EP3229959B1
公开(公告)日：2019-05-15
申请号：EP15823227.2
申请日：2015-12-09
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公开(公告)号：EP3229959A1
公开(公告)日：2017-10-18
申请号：EP15823227.2
申请日：2015-12-09
发明人： POEHMERER, Thomas , KUHN, Phillip , NOTKA, Frank , ZEIDLER, Andreas , HEIL, Korbinian , TREFZER, Axel , FONNUM, Geir , KATZEN, Federico , ANDERSSON, Kristian , LIANG, Xiquan
CPC分类号： C12N15/101 , B01J2219/00468 , B01J2219/005 , B01J2219/00653 , B01J2219/00695 , B01J2219/00722 , B01L3/502715 , B01L3/502761 , B01L2200/0642 , B01L2200/0647 , B01L2300/0819 , B01L2300/0893 , B01L2400/046 , B01L2400/0487 , B03C5/026 , B03C2201/26 , C25B3/10 , C25B9/18 , C25B11/04 , C25B15/02
摘要： The disclosure generally relates to compositions and methods for the production of nucleic acid molecules. In some aspects, the invention allows for the microscale generation of nucleic acid molecules, optionally followed by assembly of these nucleic acid molecules into larger molecules. In some aspects, the invention allows for efficient production of nucleic acid molecules (e.g., large nucleic acid molecules such as genomes).
摘要翻译： 本公开总体上涉及用于生产核酸分子的组合物和方法。 在一些方面，本发明允许微量生成核酸分子，任选地随后将这些核酸分子组装成更大的分子。 在一些方面，本发明允许有效生产核酸分子（例如大核酸分子，例如基因组）。
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公开(公告)号：EP4116338A1
公开(公告)日：2023-01-11
申请号：EP22192503.5
申请日：2013-02-08
发明人： FONNUM, Geir , MODAHL, Grete , KJUS, Nini , MOLTEBERG, Astrid Evenroed , TRAN, Diem , AASERUD, Jo , GOKMEN, M. Talha , MENCHEN, Steven , FULLER, Carl , ANDRUZZI, Luisa , HINZ, Wolfgang , GREMYACHINSKIY, Dmitriy , LIGHT, David , MASTROIANNI, Alexander , ROSENBLUM, Barnett , KHAN, Shaheer , STOLARCZYK, Craig , SOKOLSKY, Tanya
IPC分类号： C08F2/16 , C08F220/54 , C08F8/12 , C08F222/38 , C12Q1/68 , C09D5/00 , C08F2/20 , C08F2/26 , C08F230/08 , C08F257/02 , C08F220/58 , C08F220/60 , C08F8/34 , C08F130/08 , C07F7/18
摘要： A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：EP3317426A1
公开(公告)日：2018-05-09
申请号：EP16741745.0
申请日：2016-07-01
发明人： FONNUM, Geir , MENCHEN, Steven M. , LUI, Alfred , XIANG, Guobing , LARSEN, Synne
IPC分类号： C12Q1/68 , G01N33/543
CPC分类号： C12Q1/6874 , C08J7/14 , C08J2333/26 , C12Q1/6853 , C12Q1/6869 , C12Q1/6876 , C12Q2525/197 , C12Q2527/125 , C12Q2565/607 , C12Q2565/629
摘要： A polymer substrate, such as a polymer coating or a polymer hydrogel network, includes carboxyl moieties that can be used as conjugation sites to which receptor or analyte molecules can be attached. In an example, the polymer substrate includes a polyacrylamide polymer network having alkanoic acid moieties or derivatives thereof, which can react with carboxyl activating compounds to provide an activated alkanoate moieties on the polyacrylamide network Amine-terminated nucleic acids can react with the activated alkanoate moieties to capture the nucleic acid to the polymer network through an alkylamide moiety.
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公开(公告)号：EP2812339A1
公开(公告)日：2014-12-17
申请号：EP13705888.9
申请日：2013-02-08
发明人： KJUS, Nini , FONNUM, Geir , BRANCHAUD, Bruce , YING, Lai-Qiang , MENCHEN, Steven , GREMYACHINSKIY, Dmitriy , KANG, Hee Chol
IPC分类号： C07F7/18 , C08F222/38
摘要： A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
摘要翻译： 描述了甲硅烷基保护的二丙烯酰胺化合物。 形成这种化合物的方法包括在第一反应条件下将甲硅烷基化试剂与羟基化二胺化合物混合以在第一溶液中形成产物，从第一溶液中分离产物，并将产物与丙烯酰氯在第二反应条件下在 第二种形成甲硅烷基保护的二丙烯酰胺化合物的溶液。
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公开(公告)号：EP3317426B1
公开(公告)日：2020-01-15
申请号：EP16741745.0
申请日：2016-07-01
发明人： FONNUM, Geir , MENCHEN, Steven M. , LUI, Alfred , XIANG, Guobing , LARSEN, Synne
IPC分类号： C12Q1/68 , G01N33/543
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公开(公告)号：EP2812339B1
公开(公告)日：2019-11-06
申请号：EP13705888.9
申请日：2013-02-08
发明人： KJUS, Nini , FONNUM, Geir , BRANCHAUD, Bruce , YING, Lai-Qiang , MENCHEN, Steven , GREMYACHINSKIY, Dmitriy , KANG, Hee Chol
IPC分类号： C08F220/58 , C08F230/08 , C08F236/20 , C08K3/20 , C07F7/18 , C08F222/38
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