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公开(公告)号:EP2611941A4
公开(公告)日:2014-01-22
申请号:EP11822498
申请日:2011-08-30
发明人: STONE STEVEN , GUTIN ALEXANDER , WAGNER SUSANNE , REID JULIA
IPC分类号: C12Q1/68 , C12N15/11 , G01N33/574 , G06F19/10
CPC分类号: C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G06F19/20
摘要: Biomarkers and methods using the biomarkers for molecular detection and classification of disease and, particularly, molecular markers for cancer diagnosis and prognosis and methods of use thereof are provided.
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公开(公告)号:EP2591126A4
公开(公告)日:2014-01-01
申请号:EP11804357
申请日:2011-07-07
发明人: STONE STEVE , GUTIN ALEXANDER , WAGNER SUSANNE , REID JULIA
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/156 , C12Q2600/158
摘要: Biomarkers and methods using the biomarkers for the prediction of the recurrence risk of cancer in a patient are provided.
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3.GENE SIGNATURES FOR LUNG CANCER PROGNOSIS AND THERAPY SELECTION 审中-公开
标题翻译: GENSIGNATURENFÜRLUNGENKREBSPROGNOSE UNDERAPIEAUSWAHL公开(公告)号:EP2744919A4
公开(公告)日:2015-04-08
申请号:EP12825690
申请日:2012-08-17
发明人: WAGNER SUSANNE , STONE STEVEN , GUTIN ALEXANDER , REID JULIA
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/158
摘要: The invention provides for molecular classification of disease and, particularly, molecular markers for lung cancer prognosis and therapy selection and methods and systems of use thereof.
摘要翻译: 本发明提供疾病的分子分类,特别是用于肺癌预后和治疗选择的分子标志物及其使用方法和系统。
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公开(公告)号:EP2958999A4
公开(公告)日:2016-10-19
申请号:EP14754889
申请日:2014-02-21
发明人: WAGNER SUSANNE , STONE STEVEN , GUTIN ALEXANDER , REID JULIA
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/158
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公开(公告)号:EP2971178A4
公开(公告)日:2017-04-19
申请号:EP14775484
申请日:2014-03-11
发明人: STONE STEVE , PERRY MICHAEL , GUTIN ALEXANDER , THEODORESCU DAN
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/156
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6.
公开(公告)号:EP2475790A4
公开(公告)日:2013-03-20
申请号:EP10816163
申请日:2010-09-10
申请人: MYRIAD GENETICS INC , UNIV TEXAS , STONE STEVE , GUTIN ALEXANDER , FLAKE DARL , ESTEVA FRANCISCO , YU DIHUA
发明人: STONE STEVEN , GUTIN ALEXANDER , FLAKE DARL , ESTEVA FRANCISCO , YU DIHUA
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/158
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公开(公告)号:EP2531619A4
公开(公告)日:2013-08-21
申请号:EP11740448
申请日:2011-02-04
CPC分类号: C12Q1/6886 , C07K14/47 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158
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公开(公告)号:EP2794907A4
公开(公告)日:2015-08-26
申请号:EP12860530
申请日:2012-12-21
CPC分类号: C12Q1/6886 , A61K31/282 , A61K33/24 , C12Q2600/106 , C12Q2600/154 , C12Q2600/156 , C12Q2600/158
摘要: This document provides methods and materials involved in assessing samples (e.g., cancer cells) for the presence of a loss of heterozygosity (LOH) signature. For example, methods and materials for determining whether or not a cell (e.g., a cancer cell) contains an LOH signature are provided. Materials and methods for identifying cells (e.g., cancer cells) having a deficiency in homology directed repair (HDR) as well as materials and methods for identifying cancer patients likely to respond to a particular cancer treatment regimen also are provided.
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公开(公告)号:EP2539468A4
公开(公告)日:2013-08-28
申请号:EP11748075
申请日:2011-02-24
发明人: ABKEVICH VICTOR , TIMMS KIRSTEN , GUTIN ALEXANDER
CPC分类号: C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/156 , G06F19/18 , G06F19/20 , G06F19/22 , G06F19/24 , G06F19/34
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10.GENES AND GENE SIGNATURES FOR DIAGNOSIS AND TREATMENT OF MELANOMA 审中-公开
标题翻译: GENE UND GENSIGNATUREN ZUR DIAGNOSE UND BEHANDLUNG VON MELANOMEN公开(公告)号:EP2971156A4
公开(公告)日:2017-02-08
申请号:EP14769159
申请日:2014-03-12
申请人: MYRIAD GENETICS INC , WARF BRYAN , ROA BENJAMIN , GUTIN ALEXANDER , FLAKE DARL
发明人: WARF BRYAN , ROA BENJAMIN , GUTIN ALEXANDER , FLAKE DARL
CPC分类号: C12Q1/6886 , C12Q2600/158
摘要: Panels of biomarkers, methods and systems are disclosed for determining gene expression, and diagnosing and treating melanoma.
摘要翻译: 公开了用于确定基因表达以及诊断和治疗黑素瘤的生物标志物,方法和系统的组。
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