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1.发明公开
公开(公告)号：EP3355946A1
公开(公告)日：2018-08-08
申请号：EP16787588.9
申请日：2016-09-30
发明人： EDELMAN, Elazer , ARTZI, Natalie , SONG, Hyun Seok , YAMAMOTO, Yuji , YOSHIOKA, Hiroki , NAKAMOTO, Ken-ichiro
CPC分类号： C08J3/246 , A61K9/0024 , A61L27/18 , A61L27/20 , A61L27/38 , A61L27/3834 , A61L27/52 , A61L27/54 , A61L2400/06 , C08J2305/02 , C08J2343/02 , C08J2371/02 , C08L71/02
摘要： Provided herein are narrowly distributed multi-armed polyethylene glycol compounds, and hydrogels containing the same. Also provided are methods for treating, adhering, or sealing a biological tissue with hydrogels, and kits for making a hydrogel. Drug releasing compositions also are provided that include a narrowly distributed multi-armed polyethylene glycol compound.
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公开(公告)号：EP4297724A1
公开(公告)日：2024-01-03
申请号：EP22760583.9
申请日：2022-02-28
发明人： ARTZI, Natalie , DOSTA, Pere , PUIGMAL, Nuria , SOLHJOU, Zhabiz , YATIM, Karim , AZZI, Jamil
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公开(公告)号：EP4340888A1
公开(公告)日：2024-03-27
申请号：EP22805497.9
申请日：2022-05-19
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公开(公告)号：EP4297723A1
公开(公告)日：2024-01-03
申请号：EP22760580.5
申请日：2022-02-28
发明人： ARTZI, Natalie , DOSTA, Pere , PUIGMAL, Nuria
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公开(公告)号：EP3313461A1
公开(公告)日：2018-05-02
申请号：EP16738270.4
申请日：2016-06-23
CPC分类号： A61L24/043 , A61L24/0015 , A61L26/0052 , A61L26/0066 , C08L5/02 , C08L101/005
摘要： Methods, compositions, kits, and drug delivery devices are provided for treating, adhering, or sealing biological tissues. The methods include combining a first solution that includes an oligomer/polymer component and a second solution that includes a dendrimer component, and at least one of the oligomer/polymer component and dendrimer component includes at least one substituent that is capable of photoreversible dimerization. The reversible dimerization of the substituent may allow for the reversible dimerization and/or polymerization of one or more components. The substituent that is capable of photoreversible dimerization may be active by the application of light, such as UV light.
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6.发明公开CONTROLLABLY DEGRADABLE COMPOSITIONS AND METHODS 审中-公开KONTROLLERERBAR ABBAUBARE ZUSAMMENSETZUNGEN UND VERFAHREN
公开(公告)号：EP3086821A1
公开(公告)日：2016-11-02
申请号：EP14830925.5
申请日：2014-12-23
摘要： Methods for treating, adhering, or sealing biological tissue are provided. The methods include combining solutions containing a polymer component and a dendrimer component capable of reacting with each other, and at least one of the components includes a substituent capable of photoreversible dimerization that can be reversibly dimerized. Drug delivery compositions and kits containing these two components also are provided.
摘要翻译： 提供了处理，粘附或密封生物组织的方法。 所述方法包括组合含有能够彼此反应的聚合物组分和树枝状大分子组分的溶液，并且至少一种组分包括能够可逆地二聚的能够进行可光反应的二聚化的取代基。 还提供了含有这两种组分的药物递送组合物和试剂盒。
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公开(公告)号：EP3086821B1
公开(公告)日：2020-04-01
申请号：EP14830925.5
申请日：2014-12-23
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公开(公告)号：EP2696906B1
公开(公告)日：2015-07-01
申请号：EP12718802.7
申请日：2012-04-13
CPC分类号： A61L24/043 , A61L24/0005 , A61L24/0015 , A61L24/08 , A61M5/19 , A61M5/31596 , C08L5/02
摘要： Biocompatible adhesive materials, such as for use with biological tissues and/or medical implants, are provided, as well as methods and kits for making and using the biocompatible adhesive materials. The biocompatible adhesive materials include a dendrimer component and a polymer component, and may be tailored for specific tissue types and conditions.
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公开(公告)号：EP2696906A1
公开(公告)日：2014-02-19
申请号：EP12718802.7
申请日：2012-04-13
CPC分类号： A61L24/043 , A61L24/0005 , A61L24/0015 , A61L24/08 , A61M5/19 , A61M5/31596 , C08L5/02
摘要： Biocompatible adhesive materials, such as for use with biological tissues and/or medical implants, are provided, as well as methods and kits for making and using the biocompatible adhesive materials. The biocompatible adhesive materials include a dendrimer component and a polymer component, and may be tailored for specific tissue types and conditions.
摘要翻译： 提供生物相容的粘合剂材料，例如用于生物组织和/或医疗植入物，以及用于制备和使用生物相容性粘合剂材料的方法和试剂盒。 生物相容性粘合剂材料包括树枝状聚合物组分和聚合物组分，并且可以针对特定组织类型和条件而定制。
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