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    PACEMAKER WITH VASOVAGAL SYNCOPE DETECTION AND THERAPY
    6.
    发明公开
    PACEMAKER WITH VASOVAGAL SYNCOPE DETECTION AND THERAPY 审中-公开
    用激动剂同时检测和治疗的PACEMAKER

    公开(公告)号：EP1626775A1

    公开(公告)日：2006-02-22

    申请号：EP04759854.5

    申请日：2004-04-14

    申请人： MEDTRONIC, INC.

    发明人： MARKOWITZ, H. Toby ,  ERICKSON, Mark, K.

    IPC分类号： A61N1/365

    CPC分类号： A61N1/365

    摘要： A method and apparatus for cardiac pacing are provided in which pacing pulses are delivered at an increased rate (454, 470) in response to a detected intrinsic heart rate drop (505) and a special rate drop response detection scheme is temporarily disabled (510) until an intrinsic heart rate exceeds a predetermined threshold value (450). If the pacing rate reaches the lower pacing rate without sensing intrinsic activity, heart rate drop detection remains disabled and lower rate pacing continues. Rate drop detection is re-enabled (530) whenever sufficient sensed intrinsic activity indicates that a sudden intrinsic rate drop could occur again.

    摘要翻译： 提供了用于心脏起搏的方法和设备，其中响应于检测到的固有心率下降（505）以特定速率降低响应检测方案被暂时禁用（510），以增加的速率递送起搏脉冲（454,470） 直到固有心率超过预定阈值（450）。 如果起搏频率达到较低的起搏频率而未检测到内在活动，则心率下降检测将保持禁用状态，并继续进行较低频率的起搏。 只要检测到足够的内在活动表明可能再次出现突然的固有速率下降，就会重新启用速率下降检测（530）。

    DUAL CHAMBER PACING WITH ATRIAL AND VENTRICULAR INDEPENDENCE
    7.
    发明授权
    DUAL CHAMBER PACING WITH ATRIAL AND VENTRICULAR INDEPENDENCE 失效
    心房和心室双独立性腔起搏器

    公开(公告)号：EP0760697B1

    公开(公告)日：1999-06-30

    申请号：EP95917590.2

    申请日：1995-04-19

    申请人： MEDTRONIC, INC.

    发明人： WEINER, Henry L. ,  MARKOWITZ, H. Toby ,  HESS, Michael F.

    IPC分类号： A61N1/368

    CPC分类号： A61N1/368

    摘要： A rate-responsive cardiac pacemaker implements a novel pacing mode, identified as ADIR/VVIR, which is especially effective for patients with Sick Sinus Syndrome and only intermittent atrioventricular block. Within the same pacemaker circuitry, an AAIR pacemaker and a VVI pacemaker (with an escape rate below that of the AAIR pacemaker) are provided with atrial blanking following both atrial and ventricular events. Ventricular blanking after atrial pacing is minimized for better detection of R-waves following an atrial paced event.

    FAULT-TOLERANT ELECTIVE REPLACEMENT INDICATION FOR IMPLANTABLE MEDICAL DEVICE
    8.
    发明授权
    FAULT-TOLERANT ELECTIVE REPLACEMENT INDICATION FOR IMPLANTABLE MEDICAL DEVICE 失效
    容许出错的选修更换适应症用于医用可植入装置

    公开(公告)号：EP0706407B1

    公开(公告)日：1997-09-24

    申请号：EP94919995.4

    申请日：1994-05-10

    申请人： MEDTRONIC, INC.

    发明人： SHELTON, Michael B. ,  STARKSON, Ross O. ,  SCHMIDT, Craig L. ,  MARKOWITZ, H. Toby

    IPC分类号： A61N1/37 ,  G01R31/36

    CPC分类号： G01R31/3662 ,  A61N1/3708 ,  A61N1/378

    摘要： A pacemaker having a fault-tolerant elective replacement indicator (ERI) triggering scheme in which transient excursions of parameters used as criteria for triggering ERI are rejected as triggering events. Periodic assessments of certain indicia of battery depletion are made, and subjected to a long-term low-pass filtering operation in order to reduce the effects of transient excursions of the indicia which result from non-ERI conditions. Over a long period of time (e.g., a day) predetermined threshold values of the indicia of interest must be exceeded a predetermined number of times in order for the device to issue an ERI. In one disclosed embodiment of the invention, the battery's terminal voltage and internal impedance are used as indicators of the battery's depletion level. Periodically, these values are measured and converted to digital values. The digital values are subjected to a low-pass filtering operation to prevent temporary or transient excursions of the impedance and voltage curves from causing ERI to be triggered. In another disclosed embodiment of the invention, a long term fading average of periodically measured values is maintained. When the measured values are found to fulfill the ERI criteria, assessment of the parameters of interest is performed at an increased rate. While assessments are performed at the increased rate, the continuously updated fading average value must fulfill the ERI triggering criteria at least a predetermined number of times before ERI is triggered. If the fading average fails to fulfill the ERI triggering criteria the required number of times, assessments are resumed at the first, slower periodic rate.

    DUAL CHAMBER PACING WITH ATRIAL AND VENTRICULAR INDEPENDENCE
    9.
    发明公开
    DUAL CHAMBER PACING WITH ATRIAL AND VENTRICULAR INDEPENDENCE 失效
    心房和心室双独立性腔起搏器

    公开(公告)号：EP0760697A1

    公开(公告)日：1997-03-12

    申请号：EP95917590.0

    申请日：1995-04-19

    申请人： MEDTRONIC, INC.

    发明人： WEINER, Henry L. ,  MARKOWITZ, H. Toby ,  HESS, Michael F.

    IPC分类号： A61N1

    CPC分类号： A61N1/368

    摘要： A rate-responsive cardiac pacemaker implements a novel pacing mode, identified as ADIR/VVIR, which is especially effective for patients with Sick Sinus Syndrome and only intermittent atrioventricular block. Within the same pacemaker circuitry, an AAIR pacemaker and a VVI pacemaker (with an escape rate below that of the AAIR pacemaker) are provided with atrial blanking following both atrial and ventricular events. Ventricular blanking after atrial pacing is minimized for better detection of R-waves following an atrial paced event.

    CHRONICALLY-IMPLANTABLE ACTIVE FIXATION MEDICAL ELECTRICAL LEADS AND RELATED METHODS FOR NON-FLUOROSCOPIC IMPLANTATION
    10.
    发明公开
    CHRONICALLY-IMPLANTABLE ACTIVE FIXATION MEDICAL ELECTRICAL LEADS AND RELATED METHODS FOR NON-FLUOROSCOPIC IMPLANTATION 审中-公开
    与ACTIVE安装和相关方法NICHTFLUOROSKOPISCHEN植入永久性植入医用电气系统

    公开(公告)号：EP2136706A1

    公开(公告)日：2009-12-30

    申请号：EP07870059.8

    申请日：2007-12-28

    申请人： MEDTRONIC, INC.

    发明人： MARKOWITZ, H. Toby ,  GIESE, Chad ,  WALDHAUSER, Steven

    IPC分类号： A61B5/053 ,  A61N1/05

    CPC分类号： A61N1/056 ,  A61N1/0573 ,  A61N1/08

    摘要： Bio-impedance may be used for navigation systems to chronically implant pacing and defibrillation leads in the heart using a non-fluoroscopic position sensing unit (PSU), such as a modified LocaLisa® system from Medtronic Inc., which allows for variable frequency sampling of the position of electrode of a catheter. The PSU injects small AC signals via surface electrodes in three orthogonal axes, each on a slightly different frequency (e.g., near 30 KHz). Indwelling electrodes electrically connected to the PSU resolves the magnitude of induced voltage for each of the three frequencies, thus measuring voltage for each of the three axes. Voltages are divided by induced current to yield impedance in each axis for each electrode. Impedance is proportional to position within the body. Such a system requires that a conductive material, such as a retractable helical tip-electrode, be exposed during implantation. Since the tip is retracted during implantation, this disclosure provides a modified distal portion employing at least one aperture (or 'window') for fluid exposure of the helix-electrode and a deployable internal sleeve for covering the aperture(s) when the helix-electrode is extended.