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1.发明公开COMPOSITIONS COMPRISING CINNAMALDEHYDE AND ZINC AND METHODS OF USING SUCH COMPOSITIONS 审中-公开组合物肉桂醛和锌使用这类组合物方法
公开(公告)号：EP3169170A2
公开(公告)日：2017-05-24
申请号：EP15727655.1
申请日：2015-06-08
申请人： Nestec S.A.
IPC分类号： A23L33/00 , A23L33/16 , A61K31/11 , A61K33/30 , A23L33/105
摘要： Compositions comprise an amount of cinnamaldehyde that is orally tolerable, thus avoiding an unpleasant mouth feeling, and also tolerable in the gastrointestinal tract. The amount of cinnamaldehyde is supplemented by zinc, and the combination is effective to increase at least one of energy expenditure, sympathetic nervous system activity, or fat oxidation, relative to a composition lacking cinnamaldehyde and zinc but otherwise identical. The composition comprising the combination of cinnamaldehyde and zinc can be used in a method to support weight managementor promote weight loss, a method for preventing obesity or overweight, and a method for treating obesity or overweight. In an embodiment, the composition comprising cinnamaldehydeis administered to a human. The composition comprising cinnamaldehyde may be a medicament, a food product or a supplement. The composition can improve one or more of insulin sensitivity, glucose tolerance, cognitive performance, cognition, mood or memory.
摘要翻译： 组成上肉桂醛的量包括没经口服可容忍的，从而避免不愉快的口感，因此，在胃肠道耐受。 肉桂醛的量由锌补充，并且该组合可有效地增加能量消耗，交感神经系统活性，或脂肪氧化中的至少一种，相对于没有肉桂醛和锌，但其它方面相同的组合物。 包含肉桂醛和锌组成的组合的组合物可以在一个方法被用于支持重量管理导师促进体重减轻，用于预防肥胖症或超重的方法，以及用于治疗肥胖症或超重的方法。 ，实施例中的组合物，包括给予人cinnamaldehydeis。 该组合物包括肉桂醛可以是药物，食物产品或补充。 该组合物可以改善一种或多种胰岛素敏感性，葡萄糖耐受性，认知性能，认知，情绪或存储器。
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2.发明公开TREATMENT OR PREVENTION OF AUTISM DISORDERS USING MENTHOL, LINALOOL AND/OR ICILIN 审中-公开治疗综合征或孤独症障碍的预防，采用甲醇，芳樟醇和/或伊西林素
公开(公告)号：EP3003293A1
公开(公告)日：2016-04-13
申请号：EP14726348.7
申请日：2014-05-23
申请人： Nestec S.A.
发明人： CAMACHO, Susana , MICHLIG GONZALEZ, Stéphanie , LE COUTRE, Johannes , MARKRAM, Henry , PEZZOLI, Maurizio
IPC分类号： A61K31/045 , A61K31/513 , A61P25/00
CPC分类号： A61K31/513 , A23L33/105 , A23V2002/00 , A61K9/0053 , A61K31/045 , A61K2300/00 , A23V2200/322 , A23V2250/2132
摘要： Compositions for treatment or prevention of autism disorders are provided, and the compositions contain a therapeutically effective amount of a compound selected from the group consisting of Menthol, Linalool, Icilin and combinations thereof. Methods for treatment or prevention of autism disorders are also provided, and the methods include administering such compositions.
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公开(公告)号：EP3003292B1
公开(公告)日：2019-03-20
申请号：EP14726347.9
申请日：2014-05-23
申请人： Nestec S.A.
发明人： CAMACHO, Susana , MICHLIG GONZALEZ, Stéphanie , LE COUTRE, Johannes , MARKRAM, Henry , PEZZOLI, Maurizio
IPC分类号： A61K31/045 , A61K31/513 , A23L33/10 , A61P25/00
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4.发明公开
公开(公告)号：EP3407882A1
公开(公告)日：2018-12-05
申请号：EP17701647.4
申请日：2017-01-13
申请人： Nestec S.A.
发明人： ACTIS GORETTA, Lucas , PATIN, Amaury , MICHLIG GONZALEZ, Stéphanie , LEGRAND, Coline , CAMACHO, Susana , LE COUTRE, Johannes
IPC分类号： A61K31/353 , A23L33/105 , A61P9/08 , A61P9/12 , A61P3/04 , A61P3/10
CPC分类号： A61K31/353 , A23L33/105 , A23L33/40 , A23V2002/00 , A23V2200/328 , A23V2250/21 , A23V2250/2116
摘要： Compositions can comprise the catechin metabolite 3'-O-methyl-4'-O-sulfate epicatechin. In some embodiments, the composition can be used in a method for blood vessel dilation and/or increased delivery of blood flow to tissues in the body, for example by administering the composition to an individual having or at risk of high blood pressure or a cardiovascular disease. In some embodiments, the compositions are used for weight maintenance or weight loss. In further embodiments the compositions are used for treating or preventing gestational diabetes mellitus. The compositions may be administered orally as a food product in which the 3'-O-methyl-4'-O-sulfate epicatechinis present in a concentration of at least 0.01 mg/g of the food product.
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5.发明公开METHODS AND COMPOSITIONS FOR USING CINNAMALDEHYDE AND ZINC FOR WEIGHT MANAGEMENT 审中-公开方法和组合物锌，持续的称重管理和使用肉桂醛
公开(公告)号：EP3133941A1
公开(公告)日：2017-03-01
申请号：EP15711442.2
申请日：2015-03-10
申请人： Nestec S.A.
IPC分类号： A23L33/105 , A23L33/16 , A23L33/00
CPC分类号： A61K33/30 , A23L33/105 , A23L33/16 , A23L33/30 , A61K31/11
摘要： Compositions comprise an amount of cinnamaldehyde that is orally tolerable, thus avoiding an unpleasant mouth feeling, and also tolerable in the gastrointestinal tract. The amount of cinnamaldehyde is supplemented by zinc, and the combination is effective to increase at least one of energy expenditure, sympathetic nervous system activity, or fat oxidation, relative to a composition lacking cinnamaldehyde and zinc but otherwise identical. The composition comprising the combination of cinnamaldehyde and zinc can be used in a method to support weight management or promote weight loss, a method for preventing obesity or overweight, and a method for treating obesity or overweight. In an embodiment, the composition comprising cinnamaldehyde is administered to a human. The composition comprising cinnamaldehyde may be a medicament, a food product or a supplement.
摘要翻译： 组成上肉桂醛的量包括没经口服可容忍的，从而避免不愉快的口感，因此，在胃肠道耐受。 肉桂醛的量由锌补充，并且该组合可有效地增加能量消耗，交感神经系统活性，或脂肪氧化中的至少一种，相对于没有肉桂醛和锌，但其它方面相同的组合物。 包含肉桂醛和锌组成的组合的组合物可以在方法中使用，以支持体重控制或促进体重减轻，用于预防肥胖症或超重，用于治疗肥胖症或超重的方法的方法。 在向组合物，包括肉桂醛实施例是对人给药。 该组合物包括肉桂醛可以是药物，食物产品或补充。
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公开(公告)号：EP3119385B1
公开(公告)日：2018-04-25
申请号：EP15711116.2
申请日：2015-03-17
申请人： Nestec S.A.
IPC分类号： A61P1/00 , A61K31/11 , A61K31/315
摘要： Compositions comprise an amount of cinnamaldehyde that is orally tolerable, thus avoiding an unpleasant mouth feeling, and also tolerable in the gastrointestinal tract. The amount of cinnamaldehyde is supplemented by zinc, and the combination is effective to promote a swallowing reflex. The composition comprising the combination of cinnamaldehyde and zinc can be used in a method to treat dysphagia and/or prevent aspiration pneumonia from dysphagia. In an embodiment, the composition comprising cinnamaldehyde is administered to a human. The composition comprising cinnamaldehyde may be a medicament, a food product or a supplement to a food product.
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公开(公告)号：EP3024450A1
公开(公告)日：2016-06-01
申请号：EP14741598.8
申请日：2014-07-18
申请人： Nestec S.A.
摘要： Compositions contain a therapeutically effective amount of tiglic aldehyde for at least one of provoking the swallowing reflex of dysphagic patients, decreasing appetite by delaying gastric emptying, reducing body weight gain, or reducing glycemia by improving insulin sensitivity improving mood, memory or cognition. Methods are provided that include administering such compositions.
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公开(公告)号：EP2219473A1
公开(公告)日：2010-08-25
申请号：EP08850741.3
申请日：2008-11-13
申请人： Nestec S.A.
发明人： LABBE, David Philippe , RIERA, Céline , SCHLUP-OLLIVIER, Gaëlle Marie, Laure , LE COUTRE, Johannes
CPC分类号： A23C9/1307 , A23G1/48 , A23G1/52 , A23G9/32 , A23G9/36 , A23G9/42 , A23L2/56 , A23L27/10 , A23L27/11 , A23L27/14 , A23L27/204
摘要： The present invention relates to all-natural tingling compositions, to the use thereof in food products, in particular in frozen food or chilled dairy products and to a method for producing said tingling compositions.
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公开(公告)号：EP3024448B1
公开(公告)日：2019-07-03
申请号：EP14739842.4
申请日：2014-07-18
申请人： Nestec S.A.
摘要： Compositions contain a therapeutically effective amount of p-anisaldehyde for at least one of provoking the swallowing reflex of dysphagic patients, decreasing appetite by delaying gastric emptying, reducing body weight gain, or reducing glycemia by improving insulin sensitivity, or improving mood, memory or cognition. Methods are provided that include administering such compositions.
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