METHOD FOR MANUFACTURING POLYMETHOXYFLAVONES THAT ARE HIGHLY STABLE OVER TIME AND HAVE REDUCED RESIDUAL PESTICIDE LEVELS
    4.
    发明公开
    METHOD FOR MANUFACTURING POLYMETHOXYFLAVONES THAT ARE HIGHLY STABLE OVER TIME AND HAVE REDUCED RESIDUAL PESTICIDE LEVELS 审中-公开
    用于生产POLYMETHOXYFLAVONEN高稳定性时间和最少休息农药浓度

    公开(公告)号:EP2530080A1

    公开(公告)日:2012-12-05

    申请号:EP10844601.4

    申请日:2010-01-29

    申请人: Ogawa & Co., Ltd.

    摘要: There is provided a method for manufacturing inexpensive, highly safe, highly stable, versatile polymethoxyflavones that can be used in food products and easily incorporated into a variety of pharmaceutical formulations, whereby in one pass, a large quantity of polymethoxyflavones can be isolated from other components in citrus peel oil, as well as a method for its use. The method for manufacturing polymethoxyflavones from citrus plant peel oil comprises a step of removing the volatile components in citrus plant peel oil by distillation to obtain a distillation residue, a step of distilling the residue with a thin-film vacuum distillation apparatus to obtain a fraction, a step of extracting the fraction with an aqueous ethanol solution to obtain an extract, and a step of contacting active carbon with the extract after removal of the insoluble oils in the extract for refining, as a method for manufacturing polymethoxyflavones that are highly stable over time and have reduced residual pesticide levels.

    Composition providing a cooling sensation substantially similar to that provided by menthol
    5.
    发明公开
    Composition providing a cooling sensation substantially similar to that provided by menthol 有权
    Zusammensetzung mitähnlichemKühlungsempfindenwie bei薄荷醇

    公开(公告)号:EP2478777A1

    公开(公告)日:2012-07-25

    申请号:EP12157450.3

    申请日:2006-12-21

    摘要: A composition is provided that may be delivered orally or to the skin or mucous membranes and that provides substantially the same physiological effect as menthol but does not contain menthol at all or in an amount that is less than normally is required to deliver the same physiological effect. The description extends to products suitable for oral, skin or mucosal delivery that impart a menthol-like sensation and that contain the compositions described therein. Particular of these products include chewing gums and confections. Further, the description embraces methods of providing a physiological sensation substantially similar to that imparted by menthol alone by administering a composition as described herein or a product containing such a composition. Still further, the description extends to methods for providing a physiological sensation substantially similar to one aspect of the physiological sensation imparted by menthol alone or heightened or reduced when compared to menthol alone.

    摘要翻译: 提供了可以口服或皮肤或粘膜递送的组合物,并且提供与薄荷醇基本上相同的生理作用,但不包含薄荷醇,或者通常少于递送相同生理效应所需的量 。 描述延伸到适于口服,皮肤或粘膜递送的产品,其赋予薄荷醇样感觉并且含有其中所述的组合物。 这些产品的特点包括口香糖和甜食。 此外,描述包括通过施用本文所述的组合物或含有这种组合物的产品,提供基本上类似于由薄荷醇单独赋予的生理感觉的方法。 此外,该描述延伸到用于提供基本类似于单独的薄荷醇所产生的生理感觉的一个方面的生理感觉的方法,或者与单独的薄荷醇相比增强或减少。