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公开(公告)号：EP4427590A2
公开(公告)日：2024-09-11
申请号：EP24176079.2
申请日：2022-04-15
申请人： Novartis AG
发明人： FAN, Liqiong , HAINZL, Dominik , RAMOT, Roee , IYER, Shwetha , D'ALESSIO, Joseph Anthony , WUERSCH, Kuno , PISTORIUS, Dominik , MANCHADO ROBLES, Eusebio , BUNTIN, Kathrin , GABRIEL, Doris , FESSLER, Boris , MAUDENS, Pierre , ROMANET, Vincent , BLUEMMEL, Anne-Sophie , HOFFMASTER, Keith , KHERA, Eshita , YERRAMILLI-RAO, Padmaja
IPC分类号： A01N43/00
CPC分类号： C12N15/52 , C12N9/93 , C12N9/1029 , C12R2001/0120210501 , C12N9/0006 , C12N9/0071 , C07K14/705 , C12P21/02 , C07K14/4722 , C07K16/28 , A61K47/6849 , A61K47/6865 , A61K47/6811 , A61K47/6803
摘要： This application discloses microorganisms and methods of producing GNAQ/GNA11 inhibitors and methods of making antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor. The disclosure also relates to formulations comprising antibody drug conjugates of anti-PMEL17 antibodies or antigen binding fragments conjugated to a GNAQ/GNA11 inhibitor and methods of treating or preventing cancer using the formulations.
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公开(公告)号：EP4323526A1
公开(公告)日：2024-02-21
申请号：EP22726208.6
申请日：2022-04-15
申请人： Novartis AG
发明人： FAN, Liqiong , HAINZL, Dominik , RAMOT, Roee , IYER, Shwetha , D'ALESSIO, Joseph Anthony , WUERSCH, Kuno , PISTORIUS, Dominik , MANCHADO ROBLES, Eusebio , BUNTIN, Kathrin , GABRIEL, Doris , FESSLER, Boris , MAUDENS, Pierre , ROMANET, Vincent , BLUEMMEL, Anne-Sophie , HOFFMASTER, Keith , KHERA, Eshita , YERRAMILLI-RAO, Padmaja
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公开(公告)号：EP3534902A1
公开(公告)日：2019-09-11
申请号：EP17812269.3
申请日：2017-11-01
申请人： Novartis AG
发明人： FAIRHURST, Robin Alec , GRAUS PORTA, Diana , KINYAMU-AKUNDA, Jacqueline , MAHL, Andreas Joerg , MANENTI, Luigi , WEISS, Andreas , WOLF, Armin , WUERSCH, Kuno
IPC分类号： A61K31/4545 , A61K31/506 , A61P35/00
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