PERFUSION CULTURE METHOD AND PERFUSION CULTURE DEVICE FOR ORGAN OR TISSUE
    7.
    发明公开
    PERFUSION CULTURE METHOD AND PERFUSION CULTURE DEVICE FOR ORGAN OR TISSUE 有权
    器官或组织的灌注培养程序和灌注培养装置

    公开(公告)号:EP2530142A4

    公开(公告)日:2016-09-14

    申请号:EP11736981

    申请日:2011-01-25

    摘要: Disclosed are a perfusion culture method and a perfusion culture device whereby a perfusate can be delivered to all parts of an organ or tissue so that the organ or tissue can be preserved while sufficiently maintaining the function thereof. Specifically disclosed is a method for perfusion culture of an organ or tissue removed from a mammal, said organ or tissue having been removed together with a second organ or tissue connected to the aforesaid organ or tissue in vivo, which comprises a step for fixing said second organ or tissue so as to hang the aforesaid organ or tissue and a step for perfusing blood vessels in the aforesaid organ or tissue with a perfusate.

    摘要翻译: 公开了一种灌注培养方法和灌注培养装置,其中灌注液可以递送到器官或组织的所有部分,使得可以在充分保持其功能的同时保存器官或组织。 具体公开了一种用于从哺乳动物,所述器官或组织移除的器官或组织的灌注培养的方法,所述器官或组织与在体内连接到所述器官或组织的第二器官或组织一起被去除,其包括用于固定所述第二 器官或组织,以悬挂上述器官或组织,以及用灌注液灌注上述器官或组织中的血管的步骤。

    METHOD FOR MAINTAINING ORGAN OR TISSUE FOR TRANSPLANTATION USE FOR LONG PERIOD
    8.
    发明公开
    METHOD FOR MAINTAINING ORGAN OR TISSUE FOR TRANSPLANTATION USE FOR LONG PERIOD 审中-公开
    方法进行保存的机构或组织移植治疗使用经过长期

    公开(公告)号:EP2893806A4

    公开(公告)日:2016-06-01

    申请号:EP13834977

    申请日:2013-08-29

    IPC分类号: A01N1/02

    CPC分类号: A01N1/0226 A01N1/0247

    摘要: The object of the present invention is to provide a technology that enables long-term preservation while maintaining the function of an organ or tissue for transplantation. A further object is utilizing this technology to provide a technology for suppressing tissue disorder accompanying warm ischemia and reperfusion as well as restoring an organ from a cardiac arrest donor to a level compatible for transplantation. A long-term maintenance method of a mammalian organ or tissue for transplantation that employs perfusion by a perfusate etc. is provided, comprising each ofthe following steps of (a) connecting a perfusate instream cannula for streaming said perfusate into said "organ or tissue," (b) connecting a perfusate outstream cannula for streaming said perfusate out from said "organ or tissue," and (c) perfusing a perfusate comprising an oxygen carrier and a blood coagulation inhibitor into said organ or tissue.

    摘要翻译: 本发明的目的是提供一种技术那样使长期保存,同时保持器官或组织移植的功能。 进一步的目的是利用这种技术,可提供一种技术,用于抑制组织障碍伴随的暖缺血和再灌注以及从心脏骤停供体器官恢复到移植兼容的电平。 哺乳动物器官或组织移植的长期维持方法做了通过灌注液等采用灌注被提供,每个包括国税发以下(a)连接灌注液插播插管用于流式传输所述灌洗液成的步骤,所述“器官或组织, “(b)将用于流灌注液outStream插管从所述灌注液出所述”器官或组织“,以及(c)灌注灌注液包含氧载体和血液凝固抑制剂到所述器官或组织。