摘要:
The object of the present invention is to provide an implant that enables functional periodontium formation around the implant after transplantation of a dental implant. The dental implant of the present invention is characterized in that a tooth germ tissue-derived or a periodontal membrane tissue-derived cell mass is placed on the surface of the implant, the surface of the implant on which the cell mass is to be placed is the whole or a part of the surface which is surrounded by the alveolar bone of the recipient at the time of implant transplantation.
摘要:
The purpose of the present invention is to provide a method for producing a regenerative organ primordium for transplantation, said regenerative organ primordium for transplantation ensuring continuity with a recipient after transplantation and facilitating transplantation procedures. Provided is a method for producing a regenerative organ primordium provided with a guide for transplantation, said method comprising: a step for preparing a regenerative organ primordium by tightly contacting a first cell mass, which substantially consists of mesenchymal cells, with a second cell mass, which substantially consists of epithelial cells, and culturing these cell masses within a supporting medium; and a step for inserting the guide into the regenerative organ primordium.
摘要:
Disclosed are a perfusion culture method and a perfusion culture device whereby a perfusate can be delivered to all parts of an organ or tissue so that the organ or tissue can be preserved while sufficiently maintaining the function thereof. Specifically disclosed is a method for perfusion culture of an organ or tissue removed from a mammal, said organ or tissue having been removed together with a second organ or tissue connected to the aforesaid organ or tissue in vivo, which comprises a step for fixing said second organ or tissue so as to hang the aforesaid organ or tissue and a step for perfusing blood vessels in the aforesaid organ or tissue with a perfusate.
摘要:
The object of the present invention is to provide a technology that enables long-term preservation while maintaining the function of an organ or tissue for transplantation. A further object is utilizing this technology to provide a technology for suppressing tissue disorder accompanying warm ischemia and reperfusion as well as restoring an organ from a cardiac arrest donor to a level compatible for transplantation. A long-term maintenance method of a mammalian organ or tissue for transplantation that employs perfusion by a perfusate etc. is provided, comprising each ofthe following steps of (a) connecting a perfusate instream cannula for streaming said perfusate into said "organ or tissue," (b) connecting a perfusate outstream cannula for streaming said perfusate out from said "organ or tissue," and (c) perfusing a perfusate comprising an oxygen carrier and a blood coagulation inhibitor into said organ or tissue.
摘要:
[Problem] To provide a technique for regenerating hair through the transplantation of hair follicle germ in which the color of the regenerated hair is controlled. [Solution] Provided is a method for producing a regenerative hair follicle germ for transplantation in which a color of hair that grows after transplantation is controlled, said method including: preparing a first cell mass including mesenchymal cells; preparing a second cell mass including epithelial cells; preparing a cell mass including pigment stem cells; binding the cell mass including the pigment stem cells to at least one among the first cell mass and the second cell mass, and closely contacting the first cell mass and the second cell mass, at least one of which has been bound to the cell mass including the pigment stem cells, and culturing them within a support.