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公开(公告)号：EP2598480A1
公开(公告)日：2013-06-05
申请号：EP11749118.3
申请日：2011-07-27
发明人： FYFE, Matthew Colin Thor , ORTEGA MUÑOZ, Alberto , CASTRO-PALOMINO LARIA, Julio , MARTINELL PEDEMONTE, Marc , ESTIARTE-MARTÍNEZ, Maria de los Ángeles , VALLS VIDAL, Nuria
IPC分类号： C07D213/38 , C07D213/40 , C07D213/42 , C07D213/56 , C07D213/57 , C07D239/26 , C07D277/28 , C07D333/20 , C07D401/04 , C07D405/04 , C07D409/04 , C07C211/35 , C07C311/21 , A61K31/44 , A61P35/00
CPC分类号： C07C211/40 , C07B2200/07 , C07C215/64 , C07C217/74 , C07C255/53 , C07C255/54 , C07C255/59 , C07C311/08 , C07C311/09 , C07C311/21 , C07C2601/02 , C07D213/38 , C07D213/40 , C07D213/42 , C07D213/56 , C07D213/57 , C07D213/64 , C07D239/26 , C07D277/28 , C07D333/20 , C07D401/04 , C07D401/10 , C07D405/04 , C07D405/10 , C07D409/04 , C07D409/10
摘要： The invention relates to cyclopropylamine compounds, in particular the compounds of Formula (I), and their use in therapy, including e.g. in the treatment or prevention of cancer, a neurological disease or condition, or viral infection.
摘要翻译： 本发明涉及环丙胺化合物，特别是式（I）化合物及其在治疗中的用途，包括例如， 治疗或预防癌症，神经系统疾病或病症或病毒感染。
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公开(公告)号：EP3375775A1
公开(公告)日：2018-09-19
申请号：EP18165419.5
申请日：2011-07-27
发明人： ORTEGA MUÑOZ, Alberto , FYFE, Matthew Colin Thor , MARTINELL PEDEMONTE, Marc , TIRAPU FERNANDEZ DE LA CUESTA, Iñigo , ESTIARTE-MARTÍNEZ, Maria de los Ángeles
IPC分类号： C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D261/14 , C07D263/48
CPC分类号： C07D417/12 , A61K31/422 , A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/506 , C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D253/07 , C07D261/14 , C07D263/48 , C07D271/07 , C07D271/113 , C07D277/40 , C07D285/08 , C07D285/12 , C07D285/135 , C07D401/12 , C07D413/12
摘要： The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g ., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection.
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3.发明公开ARYLCYCLOPROPYLAMINE BASED DEMETHYLASE INHIBITORS OF LSD1 AND THEIR MEDICAL USE 有权芳基丙氨酰胺类LSD1二甲基酶抑制剂及其医疗用途
公开(公告)号：EP2598482A1
公开(公告)日：2013-06-05
申请号：EP11749119.1
申请日：2011-07-27
发明人： ORTEGA MUÑOZ, Alberto , FYFE, Matthew, Colin, Thor , MARTINELL PEDEMONTE, Marc , TIRAPU FERNANDEZ DE LA CUESTA, Iñigo , ESTIARTE-MARTÍNEZ, Maria de los Ángeles
IPC分类号： C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D261/14 , C07D263/48 , C07D277/40 , C07D285/12 , C07D401/12 , C07D413/12 , C07D417/12 , C07D271/07 , C07D271/113 , C07D253/07 , A61K31/44
CPC分类号： C07D417/12 , A61K31/422 , A61K31/4245 , A61K31/433 , C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D253/07 , C07D261/14 , C07D263/48 , C07D271/07 , C07D271/113 , C07D277/40 , C07D285/08 , C07D285/12 , C07D285/135 , C07D401/12 , C07D413/12
摘要： The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection. Thus, in one specific aspect the invention relates to formulas (II), (III), (IV), (V), (VI), (VII), (VIII), (IX).
摘要翻译： 本发明涉及（杂）芳基环丙胺化合物，尤其包括如本文所述和定义的式（I）化合物，及其在治疗中的用途，包括例如治疗或预防癌症，神经疾病或病症， 或病毒感染。 因此，在一个具体方面，本发明涉及式（II），（III），（IV），（V），（VI），（VII），（VIII），（IX）。
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公开(公告)号：EP2598480B1
公开(公告)日：2019-04-24
申请号：EP11749118.3
申请日：2011-07-27
发明人： FYFE, Matthew Colin Thor , ORTEGA MUÑOZ, Alberto , CASTRO-PALOMINO LARIA, Julio , MARTINELL PEDEMONTE, Marc , ESTIARTE-MARTÍNEZ, Maria de los Ángeles , VALLS VIDAL, Nuria
IPC分类号： C07D213/38 , C07D213/40 , C07D213/42 , C07D213/56 , C07D213/57 , C07D239/26 , C07D277/28 , C07D333/20 , C07D401/04 , C07D405/04 , C07D409/04 , C07C211/35 , C07C311/21 , A61K31/44 , A61P35/00
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5.发明授权ARYLCYCLOPROPYLAMINE BASED DEMETHYLASE INHIBITORS OF LSD1 AND THEIR MEDICAL USE 有权芳基丙氨酰胺类LSD1二甲基酶抑制剂及其医疗用途
公开(公告)号：EP2598482B1
公开(公告)日：2018-04-04
申请号：EP11749119.1
申请日：2011-07-27
发明人： ORTEGA MUÑOZ, Alberto , FYFE, Matthew, Colin, Thor , MARTINELL PEDEMONTE, Marc , TIRAPU FERNANDEZ DE LA CUESTA, Iñigo , ESTIARTE-MARTÍNEZ, Maria de los Ángeles
IPC分类号： A61K31/422 , A61K31/4245 , A61K31/433 , C07D285/08 , C07D285/135 , C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D263/48 , C07D277/40 , C07D401/12 , C07D417/12 , C07D271/07 , C07D271/113 , C07D253/07 , C07D261/14 , C07D285/12 , C07D413/12
CPC分类号： C07D417/12 , A61K31/422 , A61K31/4245 , A61K31/433 , A61K31/4439 , A61K31/506 , C07D213/73 , C07D237/20 , C07D239/42 , C07D241/20 , C07D253/07 , C07D261/14 , C07D263/48 , C07D271/07 , C07D271/113 , C07D277/40 , C07D285/08 , C07D285/12 , C07D285/135 , C07D401/12 , C07D413/12
摘要： The invention relates to (hetero)aryl cyclopropylamine compounds, including particularly the compounds of formula (I) as described and defined herein, and their use in therapy, including, e.g ., in the treatment or prevention of cancer, a neurological disease or condition, or a viral infection.
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