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公开(公告)号：EP1155149A1
公开(公告)日：2001-11-21
申请号：EP00908725.5
申请日：2000-02-18
申请人： PROMEGA CORPORATION
发明人： SHULTZ, John, William , LEWIS, Martin, K. , LEIPPE, Donna , MANDREKAR, Michelle , KEPHART, Daniel , RHODES, Richard, B. , ANDREWS, Christine, Ann , HARTNETT, James, Robert , GU, Trent , OLSON, Ryan, J. , WOOD, Keith, V. , WELCH, Roy
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6823 , C12Q1/04 , C12Q1/66 , C12Q1/6827 , C12Q2535/131 , C12Q2521/319 , C12Q2565/301 , C12Q2565/1015 , C12Q2537/101 , C12Q2565/627
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined endogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.
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2.发明公开METHODS FOR DETERMINING THE PRESENCE OF NUCLEIC ACID TARGET SEQUENCES AND APPLICATIONS THEREOF 审中-公开用于确定NUCLEIC靶序列及其用途
公开(公告)号：EP1155151A1
公开(公告)日：2001-11-21
申请号：EP00911863.9
申请日：2000-02-18
申请人： PROMEGA CORPORATION
发明人： SHULTZ, John, W. , LEWIS, Martin, K. , LEIPPE, Donna , MANDREKAR, Michelle , KEPHART, Daniel , RHODES, Richard, B. , ANDREWS, Christine, Ann , HARTNETT, James, R. , GU, Trent , OLSON, Ryan, J. , WOOD, Keith, V. , WELCH, Roy
IPC分类号： C12Q1/68
CPC分类号： C12Q1/689 , C12Q1/04 , C12Q1/66 , C12Q1/6823 , C12Q1/6827 , Y10T436/24 , C12Q2565/627 , C12Q2535/131 , C12Q2521/319 , C12Q2565/301 , C12Q2565/1015 , C12Q2537/101
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined exogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, determination of viral load, genotyping, medical marker diagnostics, and the like.
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3.发明公开NETWORK OF BUOYANT PARTICLES FOR BIOMOLECULE PURIFICATION AND USE OF BUOYANT PARTICLES OR NETWORK OF BUOYANT PARTICLES FOR BIOMOLECULE PURIFICATION 审中-公开NETWORK FORBIOMOLEKÜLREINIGUNGLIFT颗粒和电梯颗粒的使用或升压FOR颗粒BIOMOLEKÜLREINIGUNG网络的
公开(公告)号：EP1907585A2
公开(公告)日：2008-04-09
申请号：EP06785973.6
申请日：2006-06-30
申请人： PROMEGA CORPORATION
CPC分类号： C12N15/1006 , C12Q1/6806 , C12Q2563/149
摘要： A network of buoyant particles for clearing lysates of biological material, the network including two or more buoyant particles covalently linked together, wherein the network ranges in size from approximately 30 microns to approximately one centimeter along the network's longest dimension. The buoyant particles may have a silica surface. The network may have a density less than about 1.2 g/cm3. Methods of making the network of buoyant particles and methods of isolating target biological material using buoyant particles or a network of buoyant particles are also described.
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公开(公告)号：EP1155150A1
公开(公告)日：2001-11-21
申请号：EP00908726.3
申请日：2000-02-18
申请人： PROMEGA CORPORATION
发明人： LEWIS, Martin, K. , KEPHART, Daniel , RHODES, Richard, B. , SHULTZ, John, W. , LEIPPE, Donna , MANDREKAR, Michelle , ANDREWS, Christine, Ann , HARTNETT, James, R. , GU, Trent , WOOD, Keith, V. , WELCH, Roy
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6827 , C12Q1/6823 , C12Q2535/131 , C12Q2521/319
摘要： Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of predetermined nucleic acid target sequences using a multiplex assay format. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, genotyping, medical marker diagnostics, and the like.
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