公开(公告)号：EP1257306A1

公开(公告)日：2002-11-20

申请号：EP01916085.2

申请日：2001-02-12

申请人： Regeneration Technologies, Inc.

发明人： BIANCHI, John, R. ,  MILLS, C., Randal ,  GORHAM, P., J. ,  ESCH, Michael ,  CARTER, Kevin, C. ,  COLEMAN, Pat ,  ROSS, Kevin ,  RAMBO, Harry, W. ,  JONES, Darren, G. ,  BUSKIRK, Dayna

IPC分类号： A61L27/36 ,  A61F2/28

CPC分类号： A61L27/36 ,  A61F2/28 ,  A61F2/442 ,  A61F2/446 ,  A61F2/447 ,  A61F2002/2839 ,  A61F2002/30261 ,  A61F2002/30266 ,  A61F2002/30329 ,  A61F2002/30492 ,  A61F2002/30599 ,  A61F2002/3085 ,  A61F2002/30904 ,  A61F2220/0025 ,  A61F2230/0082 ,  A61F2250/0063

摘要： This invention provides a method for manufacture of autograft, allograft and xenograft implants which comprises assembling such implants from smaller pieces of graft materials to form a larger graft implant product.

公开(公告)号：EP1246585A2

公开(公告)日：2002-10-09

申请号：EP01902012.2

申请日：2001-01-11

申请人： Regeneration Technologies, Inc.

发明人： CARTER, Kevin, C. ,  ESCH, Michael ,  LAROCHELLE, Paul

IPC分类号： A61F2/08

CPC分类号： A61F2/0811 ,  A61B17/1635 ,  A61B17/1637 ,  A61B17/1675 ,  A61B2217/007 ,  A61F2/08 ,  A61F2002/0858 ,  A61F2002/087 ,  A61F2002/0882 ,  A61F2002/2839 ,  A61F2002/4649 ,  A61F2230/0069 ,  A61F2310/00359

摘要： Disclosed herein is an improved Bone Tendon Bone graft for use in orthopedic surgical procedures. Specifically exemplified herein is a Bone Tendon Bone graft comprising one or more bone blocks having a groove cut into the surface therefor, wherein said groove is sufficient to accommodate fixation screw. Also disclosed is a method of harvesting grafts that has improved efficiency and increases the quantity of extracted tissue and minimizes time required by surgeon for implantation.

公开(公告)号：EP1009338B1

公开(公告)日：2006-10-04

申请号：EP98941086.5

申请日：1998-08-27

申请人： Regeneration Technologies, Inc. ,  Medtronic Sofamor Danek, Inc.

发明人： GROOMS, Jamie, M. ,  CARTER, Kevin, C. ,  SANDER, Tom ,  DULEBOHN, David, H.

IPC分类号： A61F2/44

CPC分类号： A61F2/4644 ,  A61F2/3094 ,  A61F2/442 ,  A61F2/4455 ,  A61F2002/2835 ,  A61F2002/2839 ,  A61F2002/30187 ,  A61F2002/30828 ,  A61F2002/30879 ,  A61F2002/4475 ,  A61F2002/448 ,  A61F2002/4649 ,  A61F2230/0034 ,  Y10T29/49947

摘要： An implant composed substantially of cortical bone is provided for use in cervical Smith-Robinson vertebral fusion procedures. The implant is derived from allograft or autograft cortical bone sources, is machined to form a symmetrically or asymmetrically shaped (e.g. a substantially 'D'-shaped) implant having a canal running therethrough according to methods of this invention, and inserted into the space between adjacent cervical vertebrae to provide support and induce fusion of the adjacent vertebrae. Osteogenic, osteoinductive or osteoconductive materials may be packed into the canal of the implant to expedite vertebral fusion and to allow autologous bony ingrowth.

摘要翻译： 提供基本上由皮质骨组成的植入物用于颈椎Smith-Robinson椎骨融合手术。 植入物来源于同种异体移植物或自体皮质骨源，被加工以形成根据本发明的方法具有贯穿其中的通道的对称或不对称形状（例如，基本上'D形）的植入物，并插入到 邻近的颈椎提供支撑并诱导相邻椎骨的融合。 可将成骨，骨诱导或骨传导材料填充到植入物的管道中以加速脊椎融合并允许自体骨向内生长。

公开(公告)号：EP1359950A1

公开(公告)日：2003-11-12

申请号：EP01968600.5

申请日：2001-09-07

申请人： Regeneration Technologies, Inc.

发明人： BIANCHI, John, R. ,  MILLS, Randal, C. ,  GORHAM, P., J. ,  ESCH, Michael ,  CARTER, Kevin, C. ,  COLEMAN, Pat ,  ROSS, Kevin ,  RAMBO, Harry, W. ,  JONES, Darren, G. ,  BUSKIRK, Dayna

IPC分类号： A61L27/36 ,  A61F2/28

CPC分类号： A61L27/3683 ,  A61B17/1637 ,  A61B17/1671 ,  A61F2/08 ,  A61F2/0811 ,  A61F2/28 ,  A61F2/30756 ,  A61F2/3094 ,  A61F2/442 ,  A61F2/446 ,  A61F2/447 ,  A61F2/4611 ,  A61F2/4644 ,  A61F2002/2817 ,  A61F2002/2835 ,  A61F2002/2839 ,  A61F2002/30057 ,  A61F2002/30059 ,  A61F2002/30062 ,  A61F2002/30113 ,  A61F2002/30153 ,  A61F2002/30179 ,  A61F2002/30224 ,  A61F2002/30225 ,  A61F2002/30235 ,  A61F2002/30261 ,  A61F2002/30266 ,  A61F2002/3028 ,  A61F2002/30329 ,  A61F2002/30354 ,  A61F2002/30383 ,  A61F2002/30387 ,  A61F2002/30448 ,  A61F2002/30492 ,  A61F2002/30563 ,  A61F2002/30599 ,  A61F2002/30677 ,  A61F2002/30772 ,  A61F2002/30774 ,  A61F2002/30785 ,  A61F2002/30795 ,  A61F2002/30813 ,  A61F2002/30841 ,  A61F2002/3085 ,  A61F2002/30866 ,  A61F2002/30892 ,  A61F2002/30904 ,  A61F2002/30957 ,  A61F2002/30975 ,  A61F2002/448 ,  A61F2002/4649 ,  A61F2210/0004 ,  A61F2220/0025 ,  A61F2220/0033 ,  A61F2220/005 ,  A61F2230/0006 ,  A61F2230/0019 ,  A61F2230/0058 ,  A61F2230/0063 ,  A61F2230/0069 ,  A61F2230/0082 ,  A61F2250/0063 ,  A61F2310/00365 ,  A61F2310/00383 ,  A61F2310/0097 ,  A61F2310/00976 ,  A61L2/0088 ,  A61L2/025 ,  A61L27/3604 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3662 ,  A61L27/3886

摘要： This invention provides a method for manufacture of autograft, allograft and xenograft implants which comprises assembling such implants from smaller pieces of graft materials to form a larger graft implant product. One segment of an assembled graft implant is comprised of two or more discrete regions having distinct characteristics and/or properties.