RECOMBINANT CELL AND PRODUCTION METHOD FOR ISOPRENE
    4.
    发明公开
    RECOMBINANT CELL AND PRODUCTION METHOD FOR ISOPRENE 审中-公开
    重组电池及异戊二烯的生产方法

    公开(公告)号:EP2913392A1

    公开(公告)日:2015-09-02

    申请号:EP13848830.9

    申请日:2013-10-22

    IPC分类号: C12N1/21 C12N15/09 C12P5/00

    摘要: To provide a series of techniques capable of producing isoprene from syngas or the like.
    Provided is a recombinant cell prepared by introducing a nucleic acid encoding isoprene synthase into a host cell having an isopentenyl diphosphate synthesis ability by a non-mevalonate pathway, wherein the nucleic acid is expressed in the host cell, and the recombinant cell is capable of producing isoprene from at least one C1 compound selected from the group consisting of carbon monoxide, carbon dioxide, formic acid, and methanol. As the host cell, a Clostridium bacterium or a Moorella bacterium is exemplified. Also provided is a method for producing isoprene using the recombinant cell.

    摘要翻译: 提供一系列能够从合成气等生产异戊二烯的技术。 本发明提供一种重组细胞,其通过将编码异戊二烯合酶的核酸通过非甲羟戊酸途径导入具有异戊烯基二磷酸合成能力的宿主细胞中来制备,其中所述核酸在宿主细胞中表达,并且所述重组细胞能够产生 来自至少一种选自一氧化碳,二氧化碳,甲酸和甲醇的C1化合物的异戊二烯。 作为宿主细胞,例举了梭菌属细菌或穆尔氏菌属细菌。 还提供了使用重组细胞生产异戊二烯的方法。