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1.发明公开METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER 审中-公开方法用于增加甜味剂和甜味剂成分的稳定性上稳定
公开(公告)号：EP2603098A2
公开(公告)日：2013-06-19
申请号：EP11817131.3
申请日：2011-08-12
申请人： Senomyx, Inc.
CPC分类号： A23L1/22678 , A23L2/56 , A23L27/2054 , A23L27/88 , A23V2002/00 , A61K47/22 , A61K47/26
摘要： The present invention includes methods of stabilizing one or more sweet enhancers when they are exposed to a light source as well as liquid compositions containing one or more sweet enhancers and one or more photostabilizers.
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2.发明公开ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS 审中-公开ISOSORBIDDERIVATE及其作为口味变换器，调味剂和口味放大器采用
公开(公告)号：EP2254891A2
公开(公告)日：2010-12-01
申请号：EP09717709.1
申请日：2009-03-03
申请人： Senomyx, Inc.
发明人： TACHDJIAN, Catherine , KARANEWSKY, Donald S. , ADAMSKI-WERNER, Sara L. , YAMAMOTO, Jeffrey M. , SERVANT, Guy
IPC分类号： C07D493/04 , C07D493/02
CPC分类号： A23L1/22664 , A23L2/60 , A23L27/205 , A23L27/2052 , C07D493/04
摘要： The present invention provides isosorbide derivatives having the formula shown below and certain subgenera or species thereof, as flavor or taste modifiers, particularly, savory ('umami') taste modifiers, savory flavoring agents and savory flavor enhancers in foods, beverages, and other comestible compositions,
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公开(公告)号：EP2062050A2
公开(公告)日：2009-05-27
申请号：EP08770047.2
申请日：2008-06-03
申请人： Senomyx, Inc.
发明人： TACHDJIAN, Catherine , KARANEWSKY, Donald S. , TANG, Xiao-qing , LI, Xiaodong , ZHANG, Feng , SERVANT, Guy , CHEN, Qing , DARMOHUSODO, Vincent , FINE, Richard , FOTSING, Joseph R. , HAMMAKER, Jeffrey Robert , KANG, Xinshan , KIMMICH, Rachel, D.A. , KLEBANSKY, Boris , LIU, Haitian , PETROVIC, Goran , RINNOVA, Marketa , ADAMSKI-WERNER, Sara , YAMAMOTO, Jeffrey , ZHANG, Hong , ZLOTNIK, Albert , ZOLLER, Mark
IPC分类号： G01N33/53
CPC分类号： C07D513/04 , A23L2/39 , A23L2/60 , A23L27/30 , A23L27/31 , A23L27/33 , A23L27/34 , A23L27/88 , C07D215/42 , C07D215/54 , C07D215/56 , C07D239/70 , C07D239/84 , C07D239/94 , C07D239/95 , C07D285/16 , C07D417/04 , C07D417/12 , C07D471/04 , C07D487/04 , C07D491/04 , C07D491/056 , C07D493/04 , C07D495/04 , C07D495/14 , C07D513/20 , G01N33/566
摘要： The present invention includes methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors, and modifiers capable of modulating chemosensory receptors and their ligands. The present invention also includes modifiers of chemosensory receptors and their ligands having Formula (I), its subgenus, and specific compounds. Furthermore, the present invention includes ingestible compositions comprising the modifiers of chemosensory receptors and their ligands and methods of using the modifiers of chemosensory receptors and their ligands to enhance the sweet taste of an ingestible composition or treat a condition associated with a chemosensory receptor. In addition, the present invention include processes for preparing the modifiers of chemosensory receptors and their ligands.
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4.发明公开NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF 审中-公开新的传统，风味改良剂，味，增味剂，调味剂FOR UMAMI或甜和/或放大器和使用
公开(公告)号：EP1659881A2
公开(公告)日：2006-05-31
申请号：EP04816798.5
申请日：2004-08-06
申请人： Senomyx Inc.
发明人： TACHDJIAN, Catherine , PATRON, Andrew, P. , ADAMSKI-WERNER, Sara, L. , BAKIR, Farid , CHEN, Qing , DARMOHUSODO, Vincent , HOBSON, Stephen, Terrence , LI, Xiadong , QI, Ming, Cai Lun Lu , ROGERS, Daniel, Harry , RINNOVA, Marketa , SERVANT, Guy , TANG, Xiao-Qing , ZOLLER, Mark , WALLACE, Mark , XING, Amy , GUBERNATOR, Klaus
IPC分类号： A23L1/00
CPC分类号： G01N33/543 , A23L2/56 , A23L27/202 , A23L27/203 , A23L27/2054 , A23L27/88 , A23V2002/00 , A61K8/4973 , A61K8/55 , A61K47/22 , A61K47/24 , C07C233/65 , C07C235/54 , C07C275/30 , C07C275/34 , C07D209/08 , C07D209/42 , C07D213/40 , C07D213/81 , C07D213/85 , C07D215/48 , C07D217/06 , C07D231/14 , C07D261/18 , C07D263/56 , C07D271/12 , C07D275/03 , C07D277/64 , C07D285/135 , C07D307/52 , C07D307/68 , C07D307/79 , C07D307/82 , C07D307/84 , C07D317/68 , C07D333/24 , C07D333/38 , C07D401/04 , C07D405/12 , C07D409/12 , C07D417/12 , C07F9/65517 , G01N33/5041 , G01N33/566 , G01N33/74 , G01N2333/726
摘要： The present invention relates to the discovery that certain non-naturally occurring, non-peptide amide compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or taste enhancer, more particularly, savory (the “umami” taste of monosodium glutamate) or sweet taste modifiers,—savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.
摘要翻译： 本发明涉及的化合物并特异性结合T1R1 / T1R3或T1R2 / T1R3受体或其片段或子单元。 因此，本发明涉及在测定中使用异源寡聚和嵌合味觉受体T1R1包括/ T1R3和T1R2 / T1R3的标识化合物也分别鲜味味觉刺激和甜味刺激作出反应。 此外，本发明涉及到的细胞系组成性共表达T1R1和T1R3的组合稳定或瞬时那样; 或T1R2和T1R3; 组成型或诱导条件下。 在基于细胞的测定中使用的合成的细胞系，以确定鲜味和甜味调节化合物因此被提供，特别是高通量筛选测定并通过使用荧光成像的检测受体活性。
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5.发明公开
公开(公告)号：EP3431464A3
公开(公告)日：2019-07-31
申请号：EP18191450.8
申请日：2004-08-06
申请人： Senomyx Inc.
发明人： TACHDJIAN, Catherine , PATRON, Andrew, P. , ADAMSKI-WERNER, Sara, L. , BAKIR, Farid , CHEN, Qing , DARMOHUSODO, Vincent , ROGERS, Daniel, Harry , LI, Xiadong , QI, Ming, Cai Lun Lu , ROGERS, Daniel, Harry , LEBL-RINVOA, Marketa , SERVANT, Guy , TANG, Xiao-Qing , ZOLLER, Mark , WALLACE, Mark , XING, Amy , GUBERNATOR, Klaus
IPC分类号： C07C275/30 , C07C275/34 , C07C233/65 , C07C235/54 , C07D317/68 , C07D307/84 , G01N33/566 , G01N33/74 , C07D307/34 , C07D333/02 , C07D221/00 , C07D247/00 , C07D261/00 , C07D283/00 , A23L27/20
摘要： The present invention relates to the discovery that certain non-naturally occurring, non-peptide arride compounds and amide derivatives, such as oxalamides, ureas, and acrylamides, are useful flavor or taste modifiers, such as a flavoring or flavoring agents and flavor or trite enhancer, more particularly, savory (the "umami" taste of monosodium glutamate) or sweet taste modifiers, - savory or sweet flavoring agents and savory or sweet flavor enhancers, for food, beverages, and other comestible or orally administered medicinal products or compositions.
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公开(公告)号：EP1659881B1
公开(公告)日：2019-04-03
申请号：EP04816798.5
申请日：2004-08-06
申请人： Senomyx Inc.
发明人： TACHDJIAN, Catherine , PATRON, Andrew, P. , ADAMSKI-WERNER, Sara, L. , BAKIR, Farid , CHEN, Qing , DARMOHUSODO, Vincent , HOBSON, Stephen, Terrence , LI, Xiadong , QI, Ming, Cai Lun Lu , ROGERS, Daniel, Harry , RINNOVA, Marketa , SERVANT, Guy , TANG, Xiao-Qing , ZOLLER, Mark , WALLACE, Mark , XING, Amy , GUBERNATOR, Klaus
IPC分类号： C07C275/30 , C07C275/34 , C07C233/65 , C07C235/54 , C07D317/68 , C07D307/84 , G01N33/566 , G01N33/74 , A23L27/20
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公开(公告)号：EP3085699A3
公开(公告)日：2016-11-23
申请号：EP16167988.1
申请日：2009-07-29
申请人： Senomyx, Inc.
发明人： TACHDJIAN, Catherine , KARANEWSKY, Donald, S. , TANG, Xiao, Qing , CHEN, Qing , RASHID, Tayyab , LEVIN, Daniel , LEEMING, Peter
IPC分类号： C07D285/24 , C07D285/20 , C07D285/15
CPC分类号： C07D285/16 , C01B21/096 , C07C231/02 , C07C231/14 , C07C235/20 , C07C237/44 , C07C253/30 , C07C255/54 , C07C255/57 , C07C255/59 , C07C303/40 , C07C307/10
摘要： The present invention includes methods/processes and intermediates for preparing sweet tast enhancers which are 4-aminobenzo[c][1,2,6]thiadiazin-5-yloxy derivatives.
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公开(公告)号：EP3085699A2
公开(公告)日：2016-10-26
申请号：EP16167988.1
申请日：2009-07-29
申请人： Senomyx, Inc.
发明人： TACHDJIAN, Catherine , KARANEWSKY, Donald, S. , TANG, Xiao, Qing , CHEN, Qing , RASHID, Tayyab , LEVIN, Daniel , LEEMING, Peter
IPC分类号： C07D285/24 , C07D285/20 , C07D285/15
CPC分类号： C07D285/16 , C01B21/096 , C07C231/02 , C07C231/14 , C07C235/20 , C07C237/44 , C07C253/30 , C07C255/54 , C07C255/57 , C07C255/59 , C07C303/40 , C07C307/10
摘要： The present invention includes methods/processes and intermediates for preparing sweet tast enhancers which are 4-aminobenzo[c][1,2,6]thiadiazin-5-yloxy derivatives.
摘要翻译： 本发明包括用于制备甜TAST增强剂是4-氨基苯并[c] [1,2,6]噻二嗪-5-基氧基衍生物的方法/过程和中间体。
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公开(公告)号：EP2742026B1
公开(公告)日：2016-10-05
申请号：EP12824307.8
申请日：2012-08-10
申请人： Senomyx, Inc.
发明人： TACHDJIAN, Catherine , TANG, Xiao Qing , KARANEWSKY, Donald S. , SERVANT, Guy , LI, Xiaodong , ZHANG, Feng , CHEN, Qing , ZHANG, Hong , DAVIS, Timothy , DARMOHUSODO, Vincent , WONG, Melissa , SELCHAU, Victor
IPC分类号： A23L27/00 , A23L2/60 , C07D215/42 , C07D215/54 , C07D401/12 , C07D405/12 , C07D451/06
CPC分类号： C07D405/12 , A23L2/60 , A23L27/88 , A23V2002/00 , A61K47/22 , C07D215/42 , C07D215/54 , C07D401/12 , C07D451/06
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10.发明授权Compounds that inhibit (block) bitter taste in compositions and use thereof 有权化合物，组合物中的苦味抑制（块），并使用其
公开(公告)号：EP2487169B1
公开(公告)日：2015-05-20
申请号：EP12162534.7
申请日：2008-08-19
申请人： Senomyx, Inc.
发明人： LI, Xiaodong , DARMOHUSODO, Vincent , ARELLANO, Melissa , SELCHAU, Victor , CHING, Brett Weylan , KARANEWSKY, Donald S. , BRUST, Paul , LING, Jing , ZHAO, Wen , Priest, Chad , PATRON, Andrew , TACHDJIAN, Catherine , XU, Hong , LI, Qing , PRONIN, Alexey , SERVANT, Guy , ZHANG,, Lan , BRADY, Thomas
IPC分类号： C07D307/14 , C07D317/58 , C07D333/20 , C07C311/00 , G01N33/53 , A61K31/34
CPC分类号： C07C311/17 , A23L27/86 , A61K8/46 , A61K8/466 , A61K8/4933 , A61K8/494 , A61K8/4973 , A61K8/498 , A61K8/4986 , A61K31/135 , A61K31/4439 , A61K31/485 , A61K31/60 , A61K31/704 , A61K45/06 , A61Q11/00 , C07C233/73 , C07C311/04 , C07C311/13 , C07C311/16 , C07C311/18 , C07C311/19 , C07C311/20 , C07C311/21 , C07C311/29 , C07C311/46 , C07C323/49 , C07C335/16 , C07C335/18 , C07D213/42 , C07D213/71 , C07D217/08 , C07D223/18 , C07D307/14 , C07D307/52 , C07D317/58 , C07D333/20 , C07D333/34 , A61K2300/00
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