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公开(公告)号：EP3135315A1
公开(公告)日：2017-03-01
申请号：EP15783466.4
申请日：2015-04-20
Inventor： OKAMURA, Yosuke , NAGASE, Yu , KOMACHI, Takuya , HOCHI, Motonori , SEKIDO, Yuki , ARAKANE, Toru
CPC classification number: A61L31/00 , A61L15/16 , A61L15/24 , A61L15/26 , A61L15/28 , A61L15/64 , A61L31/042 , A61L31/048 , A61L31/06 , A61L31/148 , A61L2400/12 , B32B7/045 , B32B9/02 , B32B9/04 , B32B9/045 , B32B27/08 , B32B27/306 , B32B27/36 , B32B2250/05 , B32B2250/24 , B32B2250/44 , B32B2307/7163 , B32B2307/73 , B32B2535/00 , C08L67/04 , C08L5/04 , C08L29/04
Abstract: The present invention provides a polymer laminate in which 2-100 layers each containing a biodegradable resin and having a thickness of 10 nm-400 nm are laminated, the thickness of at least one of the outermost layers is 10 nm-180 nm, and the outermost layers are joined to each other. By the present invention, a polymer laminate excellent in biocompatibility and mechanical strength and suitable to medical applications such as wound dressings and antiadhesive materials can be obtained.
Abstract translation: 本发明提供一种聚合物层叠体，其中层叠2〜100层各自含有生物降解性树脂，厚度为10nm〜400nm的聚合物层叠体，至少一层最外层的厚度为10nm〜180nm， 最外层彼此连接。 通过本发明，可以获得生物相容性和机械强度优异且适用于医疗用途如伤口敷料和防粘附材料的聚合物层压体。
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公开(公告)号：EP2082869B1
公开(公告)日：2015-09-16
申请号：EP07831170.1
申请日：2007-10-29
Applicant: Takeoka, Shinji , Nanotheta Co., Ltd. , Toray Industries, Inc.
Inventor： TAKEOKA, Shinji , OKAMURA, Yosuke , FUJIE, Toshinori , UTSUNOMIYA, Saori , GOTO, Takahiro
CPC classification number: B32B37/02 , A61K9/0014 , A61K9/70 , A61K9/7007 , B32B38/10 , C08J5/18 , C08J7/12 , C12N5/0068 , C12N2535/10 , Y10T156/10 , Y10T428/31504
Abstract: A thin film polymer structure having a functional substance on the face (A surface) and reverse face (B surface) of the film, obtained by the steps of: (a) causing polyfunctional molecules to adsorb to an area of an arbitrary shape in an interface between a substrate body and a liquid phase; (b) polymerizing and/or crosslinking the adsorbing polyfunctional molecules to form a polymer thin film; (c) bonding a functional substance to the A surface of the formed thin film and then (d) forming a soluble support film thereon; exfoliating the thin film and the soluble support film from the substrate body; (e) bonding to the B surface of the thin film a functional substance identical to or different from the abovementioned functional substance and then dissolving the soluble support film with a solvent. A method for preparing a thin film molecular structure having a functional substance on the face (A surface) and reverse face (B surface) of the film is offered through the above process.
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公开(公告)号：EP2957423B1
公开(公告)日：2018-01-17
申请号：EP15179184.5
申请日：2007-10-29
Applicant: Takeoka, Shinji , Nanotheta Co., Ltd. , TORAY INDUSTRIES, INC.
Inventor： TAKEOKA, Shinji , OKAMURA, Yosuke , FUJIE, Toshinori , GOTO, Takahiro , UTSUNOMIYA, Saori
IPC: B32B9/00 , B82B1/00 , B82B3/00 , C08J5/18 , C08J7/12 , A61K9/00 , A61K9/70 , B32B37/02 , B32B38/10 , C12N5/00
CPC classification number: B32B37/02 , A61K9/0014 , A61K9/70 , A61K9/7007 , B32B38/10 , C08J5/18 , C08J7/12 , C12N5/0068 , C12N2535/10 , Y10T156/10 , Y10T428/31504
Abstract: A thin film polymer structure having a functional substance on the face (A surface) and reverse face (B surface) of the film, obtained by the steps of: (a) causing polyfunctional molecules to adsorb to an area of an arbitrary shape in an interface between a substrate body and a liquid phase; (b) polymerizing and/or crosslinking the adsorbing polyfunctional molecules to form a polymer thin film; (c) bonding a functional substance to the A surface of the formed thin film and then (d) forming a soluble support film thereon; exfoliating the thin film and the soluble support film from the substrate body; (e) bonding to the B surface of the thin film a functional substance identical to or different from the abovementioned functional substance and then dissolving the soluble support film with a solvent. A method for preparing a thin film molecular structure having a functional substance on the face (A surface) and reverse face (B surface) of the film is offered through the above process.
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公开(公告)号：EP2957423A1
公开(公告)日：2015-12-23
申请号：EP15179184.5
申请日：2007-10-29
Applicant: Takeoka, Shinji , Nanotheta Co., Ltd. , TORAY INDUSTRIES, INC.
Inventor： TAKEOKA, Shinji , OKAMURA, Yosuke , FUJIE, Toshinori , GOTO, Takahiro , UTSUNOMIYA, Saori
IPC: B32B9/00 , B82B1/00 , B82B3/00 , C08J5/18 , C08J7/12 , A61K9/00 , A61K9/70 , B32B37/02 , B32B38/10 , C12N5/00
CPC classification number: B32B37/02 , A61K9/0014 , A61K9/70 , A61K9/7007 , B32B38/10 , C08J5/18 , C08J7/12 , C12N5/0068 , C12N2535/10 , Y10T156/10 , Y10T428/31504
Abstract: Disclosed is a thin film-like polymer structure which is obtained by the steps described below and has a functional substance on the front surface (surface A) and the back surface (surface B). Also disclosed is a method for preparing such a thin film-like polymer structure. (a) a step wherein polyfunctional molecules are adsorbed on an arbitrarily shaped region at the interface of a base with a liquid phase (b) a step wherein a polymer thin film is formed by polymerizing and/or crosslinking the adsorbed polyfunctional molecules (c) a step wherein a functional substance is bonded onto the surface A of the thus-formed thin film (d) a step wherein a soluble supporting film is formed on the thin film, and then the thin film and the supporting film are removed from the base (e) a step wherein a functional substance is bonded onto the surface B of the thin film, and then the supporting film is dissolved by a solvent.
Abstract translation: 公开了一种薄膜状聚合物结构，其通过下述步骤获得，并且在前表面（表面A）和背面（表面B）上具有功能性物质。 还公开了制备这种薄膜状聚合物结构的方法。 （a）其中多官能分子吸附在碱与液相界面处的任意形状区域（b）通过使吸附的多官能分子（c）聚合和/或交联而形成聚合物薄膜的步骤， 将功能性物质结合到如此形成的薄膜（d）的表面A上的步骤，其中在薄膜上形成可溶性支撑膜，然后从基底去除薄膜和支撑膜 （e）将功能性物质结合到薄膜的表面B上，然后通过溶剂使支持膜溶解的工序。
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