公开(公告)号：EP3207477A1

公开(公告)日：2017-08-23

申请号：EP15788529.4

申请日：2015-10-19

申请人： The Cleveland Clinic Foundation

发明人： SRIVASTAVA, Sunil K. ,  EHLERS, Justis P. ,  TAO, Yuankai K.

IPC分类号： G06F19/00

CPC分类号： A61F9/0017 ,  A61B3/102 ,  A61F9/0026 ,  G06F19/00 ,  G16H10/60

摘要： Systems and methods are provided for image-guided delivery of therapeutics to an eye. An optical coherence tomography (OCT) imager is configured to produce at least one OCT image of the eye. A therapeutic delivery system is configured to deliver a therapeutic to the eye through a distal end of a delivery mechanism. A system control is configured to determine a position of the distal end of the delivery mechanism and control the therapeutic delivery system according to at least the determined position.

摘要翻译： 系统和方法被提供用于将图像引导的治疗剂递送到眼睛。 光学相干断层扫描（OCT）成像器被配置为产生眼睛的至少一个OCT图像。 治疗性递送系统构造成通过递送机构的远端将治疗剂递送至眼睛。 系统控制器被配置为确定输送机构的远端的位置并且根据至少确定的位置来控制治疗输送系统。

公开(公告)号：EP2830480A2

公开(公告)日：2015-02-04

申请号：EP13714506.6

申请日：2013-03-26

申请人： THE CLEVELAND CLINIC FOUNDATION

发明人： EHLERS, Justis P. ,  XU, David ,  KAISER, Peter K. ,  DUPPS, William J. ,  SRIVASTAVA, Sunil K.

IPC分类号： A61B5/00

CPC分类号： G06T7/0012 ,  A61B5/0066 ,  G06T7/0016 ,  G06T7/11 ,  G06T7/12 ,  G06T7/162 ,  G06T7/62 ,  G06T17/20 ,  G06T2207/10101 ,  G06T2207/20016 ,  G06T2207/20072 ,  G06T2207/30041

摘要： Systems and methods are provided for volumetric analysis of pathologies. A segmentation component is configured to determine, for each of a series of images of a region of interest containing a pathological feature, a set of segmentation boundaries within the image representing a cross-section of the pathological feature. A mesh generation component is configured to link the sets of segmentation boundaries from adjacent images in the series of images to generate a polygonal mesh representing a volumetric reconstruction of the pathological feature. A volumetric measurement component is configured to calculate volumetric parameters from the volumetric reconstruction representing the pathological feature. A user interface is configured to provide the calculated volumetric parameters to an associated display.

摘要翻译： 提供系统和方法用于病理学的体积分析。 分割组件被配置为针对包含病理特征的感兴趣区域的一系列图像中的每一个来确定表示病理特征的横截面的图像中的分割边界的集合。 网格生成组件被配置为将所述一系列图像中的相邻图像的分割边界集合链接以生成表示病理特征的体积重建的多边形网格。 体积测量部件被配置为从表示病理特征的体积重建计算体积参数。 用户界面被配置为将计算的体积参数提供给相关联的显示。

公开(公告)号：EP2950763A1

公开(公告)日：2015-12-09

申请号：EP14706387.9

申请日：2014-02-04

申请人： THE CLEVELAND CLINIC FOUNDATION

发明人： EHLERS, Justis P. ,  SRIVASTAVA, Sunil K. ,  TAO, Yuankai

IPC分类号： A61F9/007 ,  G01B9/02 ,  A61B19/00 ,  A61B17/00

CPC分类号： A61B5/061 ,  A61B3/102 ,  A61B90/37 ,  A61B2017/00115 ,  A61B2017/00119 ,  A61B2034/2048 ,  A61B2090/062 ,  A61B2090/3735 ,  A61F9/007 ,  G01B9/02091

摘要： Systems and methods are provided for tracking a depth of a surgical instrument in an optical coherence tomography (OCT) guided surgical procedure. An OCT device (12) is configured to image a region of interest (14) to provide OCT data. A scan processor (16) is configured to determine a relative position of the instrument (18) and a target (20) within the region of interest from at least the OCT data, where the instrument is one of in front of the target, within the target, or below the target. A feedback element (22) is configured to communicate the relative position of the instrument and the target to a user in a human comprehensible form.

公开(公告)号：EP2844127A2

公开(公告)日：2015-03-11

申请号：EP13724961.1

申请日：2013-05-06

申请人： THE CLEVELAND CLINIC FOUNDATION

发明人： EHLERS, Justis P. ,  SRIVASTAVA, Sunil K. ,  TAO, Yuankai

IPC分类号： A61B3/10 ,  A61F9/007

CPC分类号： A61B5/065 ,  A61B2090/3735 ,  G01B9/0205 ,  G01B9/02091

摘要： Assemblies are provided for use as surgical instruments in optical coherence tomography (OCT) assisted surgical procedures. Each assembly includes a working assembly, formed from a material selected for desirable optical properties or modified to increase the visibility of the material in an OCT scan, and a handle attached to the working assembly.

公开(公告)号：EP3192051A1

公开(公告)日：2017-07-19

申请号：EP15772072.3

申请日：2015-09-08

申请人： The Cleveland Clinic Foundation

发明人： SRIVASTAVA, Sunil K. ,  EHLERS, Justis P.

IPC分类号： G06T7/00 ,  G06T7/20

CPC分类号： G06T7/0012 ,  A61B3/145 ,  G06T7/0016 ,  G06T7/11 ,  G06T7/187 ,  G06T7/254 ,  G06T7/30 ,  G06T7/33 ,  G06T11/003 ,  G06T2207/10016 ,  G06T2207/20084 ,  G06T2207/30041 ,  G06T2207/30101 ,  G06T2207/30104 ,  G06T2211/404

摘要： Systems and methods are provided for automated analysis of angiographic images. An angiographic imaging system is configured to capture a first image of a region of interest, representing a first time, and a second image of a region of interest, representing a second time. A registration component is configured to register the first image to the second image. A difference component is configured to generate a difference image from the first image and the second image. A pattern recognition component is configured to assign a clinical parameter to the region of interest from the difference image and at least one of the first image and the second image.

摘要翻译： 系统和方法被提供用于血管造影图像的自动分析。 血管造影成像系统被配置为捕获代表第一时间的感兴趣区域的第一图像和代表第二时间的感兴趣区域的第二图像。 注册组件被配置为将第一图像注册到第二图像。 差异组件被配置为从第一图像和第二图像生成差异图像。 模式识别组件被配置为根据差异图像以及第一图像和第二图像中的至少一个将临床参数分配给感兴趣区域。