公开(公告)号：EP2567218A4

公开(公告)日：2017-11-08

申请号：EP11777881

申请日：2011-04-25

Applicant: UNIV CALIFORNIA

Inventor： OZCAN AYDOGAN ,  COSKUN AHMET F ,  SENCAN IKBAL ,  SU TING-WEI

IPC: G01N21/64 ,  H01L27/146

CPC classification number: H01L27/14625 ,  G01N21/64 ,  G01N21/6456 ,  G01N21/648 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/0833

公开(公告)号：EP2656066A4

公开(公告)日：2017-11-08

申请号：EP11850829

申请日：2011-12-21

Applicant: UNIV CALIFORNIA

Inventor： OZCAN AYDOGAN ,  ZHU HONGYING ,  MAVANDADI SAM

IPC: G01N21/64 ,  B01L3/00 ,  B01L9/00 ,  G01N15/14 ,  G01N33/18 ,  G02B7/00 ,  G02B7/02 ,  G02B13/00 ,  H04M1/02 ,  H04M1/21 ,  H04N5/225

CPC classification number: G01N21/6458 ,  B01L3/502715 ,  B01L9/527 ,  B01L2300/0654 ,  B01L2300/0816 ,  G01N15/1436 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/648 ,  G01N2015/144 ,  G01N2021/6467 ,  G01N2021/6482 ,  G01N2201/0221 ,  G01N2201/0693 ,  G02B7/006 ,  G02B7/02 ,  G02B13/0025 ,  H04M1/0254 ,  H04M1/21 ,  H04M2250/52 ,  H04N5/2254

公开(公告)号：EP2812675A4

公开(公告)日：2015-10-28

申请号：EP12867945

申请日：2012-05-31

Applicant: UNIV CALIFORNIA

Inventor： OZCAN AYDOGAN ,  MUDANYALI ONUR ,  DIMITROV STOYAN ,  SIKORA UZAIR ,  PADMANABHAN SWATI ,  NAVRUZ ISA

IPC: G01N21/64 ,  G01N21/01 ,  G01N21/77 ,  G01N21/82 ,  G01N21/84 ,  G01N33/543 ,  G01N33/569 ,  G06F17/30 ,  G06F19/00 ,  G06K7/10

CPC classification number: G06F19/3487 ,  B01L2300/0825 ,  G01N21/01 ,  G01N21/645 ,  G01N21/8483 ,  G01N33/543 ,  G01N33/56905 ,  G01N33/5695 ,  G01N33/56988 ,  G01N2021/0118 ,  G01N2021/7786 ,  G01N2021/825 ,  G01N2021/8488 ,  G01N2201/0221 ,  G01N2201/062 ,  G01N2201/0634 ,  G06F17/30424 ,  G06K7/10732 ,  G06K7/10831 ,  G16H15/00 ,  Y02A90/22 ,  Y02A90/24 ,  Y02A90/26

Abstract: A portable rapid diagnostic test reader system includes a mobile phone having a camera and one or more processors contained within the mobile phone and a modular housing configured to mount to the mobile phone. The modular housing including a receptacle configured to receive a sample tray holding a rapid diagnostic test. At least one illumination source is disposed in the modular housing and located on one side of the rapid diagnostic test. An optical demagnifier is disposed in the modular housing interposed between the rapid diagnostic test and the mobile phone camera.

Abstract translation: 便携式快速诊断测试读取器系统包括具有照相机和包含在移动电话内的一个或多个处理器的移动电话和被配置为安装到移动电话的模块化外壳。 模块化壳体包括被配置为容纳保持快速诊断测试的样品盘的容器。 至少一个照明源设置在模块化壳体中，并位于快速诊断测试的一侧。 光学消音器设置在插入快速诊断测试和移动电话摄像机之间的模块化壳体中。

公开(公告)号：EP3175302A4

公开(公告)日：2018-03-28

申请号：EP15827025

申请日：2015-07-31

Applicant: UNIV CALIFORNIA

Inventor： OZCAN AYDOGAN ,  GREENBAUM ALON ,  ZHANG YIBO ,  FEIZI ALBORZ ,  LUO WEI

IPC: G03H1/04 ,  G03H1/00

CPC classification number: G03H1/0005 ,  G01N15/1429 ,  G01N15/1434 ,  G01N15/1475 ,  G01N2015/1006 ,  G01N2015/144 ,  G01N2015/1445 ,  G01N2015/1454 ,  G03H1/0443 ,  G03H1/0866 ,  G03H1/0891 ,  G03H2001/005 ,  G03H2001/0447 ,  G03H2001/0454 ,  G03H2001/046 ,  G03H2001/0816 ,  G03H2001/0883 ,  G03H2001/2655 ,  G03H2210/42 ,  G03H2226/02 ,  G03H2227/03 ,  H04N5/2256 ,  H04N5/23238

Abstract: A method for lens-free imaging of a sample or objects within the sample uses multi-height iterative phase retrieval and rotational field transformations to perform wide FOV imaging of pathology samples with clinically comparable image quality to a benchtop lens-based microscope. The solution of the transport-of-intensity (TIE) equation is used as an initial guess in the phase recovery process to speed the image recovery process. The holographically reconstructed image can be digitally focused at any depth within the object FOV (after image capture) without the need for any focus adjustment, and is also digitally corrected for artifacts arising from uncontrolled tilting and height variations between the sample and sensor planes. In an alternative embodiment, a synthetic aperture approach is used with multi-angle iterative phase retrieval to perform wide FOV imaging of pathology samples and increase the effective numerical aperture of the image.

公开(公告)号：EP2661603A4

公开(公告)日：2014-07-23

申请号：EP12731935

申请日：2012-01-05

Applicant: UNIV CALIFORNIA

Inventor： OZCAN AYDOGAN ,  ISIKMAN SERHAN OMER ,  BISHARA WAHEB

IPC: G01B9/02 ,  G01B11/24

CPC classification number: G01B9/02047 ,  G01B9/02041 ,  G01B9/02091 ,  G01N21/453 ,  G01N21/4795 ,  G02B21/0008 ,  G02B21/06 ,  G02B21/367 ,  G03H1/0005 ,  G03H1/02 ,  G03H1/0443 ,  G03H1/0866 ,  G03H1/265 ,  G03H2001/005 ,  G03H2001/0212 ,  G03H2001/0447 ,  G03H2001/046 ,  G03H2210/30 ,  G03H2210/62 ,  G03H2222/24 ,  G03H2222/34 ,  G03H2223/16 ,  G03H2227/02 ,  G03H2227/03 ,  G03H2240/56

Abstract: A lens-free system for the three-dimensional imaging of objects contained within a sample places a sample holder between an image sensor and an illumination source, with the sample-sensor distance being much smaller than the sample-illumination source distance. Holographic images are taken at different angles as well as different lateral jogs within a single angle and are reconstructed into a three dimensional image of objects within the sample. The system may be a hand held, portable unit.

Abstract translation: 包含在样品中的物体的三维成像系统包括图像传感器，被配置为保持样本的样本保持器，与图像传感器相邻设置的样本保持器以及包括部分相干光的照明源。 照明源被配置为通过插入在照明源和样本保持器之间的孔径，光纤电缆或光波导中的至少一个来照亮样品，其中照明源被配置为通过多个不同的 角。

公开(公告)号：EP2491366A4

公开(公告)日：2014-04-09

申请号：EP10825529

申请日：2010-10-19

Applicant: UNIV CALIFORNIA

Inventor： OZCAN AYDOGAN ,  ISIKMAN SERHAN OMER ,  OZTOPRAK CHETIN

IPC: G01N1/28

CPC classification number: G03H1/06 ,  G01N15/1475 ,  G01N15/1484 ,  G01N21/6456 ,  G01N2015/1006 ,  G01N2015/1454 ,  G01N2021/6471 ,  G01N2021/6482 ,  G01N2021/6484 ,  G01N2201/0833 ,  G03H1/041 ,  G03H1/0443 ,  G03H1/0866 ,  G03H2001/0447 ,  G03H2001/0454 ,  G03H2001/0816 ,  G03H2001/0825 ,  G03H2001/2284 ,  G03H2222/13 ,  G03H2222/22 ,  G03H2222/24 ,  G03H2222/34 ,  G03H2223/18 ,  G03H2226/11 ,  G03H2227/02 ,  G03H2240/62