公开(公告)号：EP2684946A4

公开(公告)日：2015-01-07

申请号：EP12754214

申请日：2012-03-06

Applicant: UNIV OSAKA PREFECT PUBLIC CORP ,  SHARP KK

Inventor： TOKONAMI SHIHO ,  SHIIGI HIROSHI ,  NAGAOKA TSUTOMU ,  IKEMIZU MUGIHEI ,  TAKAHASHI MARI

IPC: C12M1/34 ,  C12Q1/04 ,  C25D5/00 ,  G01N33/543 ,  G01N33/569

CPC classification number: C12Q1/04 ,  C25D5/00 ,  G01N33/5438 ,  G01N33/569 ,  Y10T428/24479

Abstract: The present invention provides a sensor including a detection unit having a detection electrode and a polymer layer that is disposed on the detection electrode and includes a mold having a three-dimensional structure complementary to a steric structure of a microorganism to be detected. The sensor detects the microorganism based on a state of capturing the microorganism in the mold. The polymer layer is formed by a manufacturing method including: a polymerization step of polymerizing a monomer in the presence of the microorganism to be detected, to form the polymer layer having captured the microorganism on the detection electrode; a destruction step of partially destroying the microorganism captured in the polymer layer; and a peroxidation step of peroxidizing the polymer layer to release the microorganism from the polymer layer.

公开(公告)号：EP3139166A4

公开(公告)日：2017-04-19

申请号：EP15786712

申请日：2015-04-30

Applicant: UNIV OSAKA PREFECT PUBLIC CORP ,  SHARP KK

Inventor： TOKONAMI SHIHO ,  NAKASE IKUHIKO

IPC: C12M1/34 ,  C08G73/06 ,  C12M1/12 ,  G01N33/50 ,  G01N33/574

CPC classification number: C12M25/02 ,  C08G73/0266 ,  C08G73/0611 ,  G01N33/5091 ,  G01N33/543 ,  G01N33/566 ,  G01N33/574 ,  G01N2600/00

公开(公告)号：EP3141300A4

公开(公告)日：2017-09-20

申请号：EP15788799

申请日：2015-05-08

Applicant: UNIV OSAKA PREFECT PUBLIC CORP ,  SHARP KK

Inventor： IIDA TAKUYA ,  TOKONAMI SHIHO ,  NAKASE IKUHIKO ,  NISHIMURA YUSHI ,  YAMAMOTO YASUYUKI

IPC: B01J19/00 ,  C12M1/26 ,  C12M1/34 ,  G01N15/00 ,  G01N15/14

CPC classification number: G01N1/44 ,  B01J19/00 ,  B01J19/0046 ,  B01J2219/00441 ,  B01J2219/00468 ,  B01J2219/00711 ,  C12M1/26 ,  C12M1/34 ,  C12M35/02 ,  G01N15/00 ,  G01N15/14

公开(公告)号：EP2993460A4

公开(公告)日：2017-04-26

申请号：EP14804538

申请日：2014-05-30

Applicant: UNIV OSAKA PREFECT PUBLIC CORP

Inventor： IIDA TAKUYA ,  TOKONAMI SHIHO

IPC: G01N21/17 ,  C12Q1/68 ,  G01N21/3577 ,  G01N21/41 ,  G01N21/552 ,  G01N21/65 ,  G01N33/53 ,  G01N33/543 ,  G01N33/553

CPC classification number: G01N33/54346 ,  C12Q1/6834 ,  C12Q2563/155 ,  C12Q2565/628 ,  G01N21/21 ,  G01N21/554 ,  G01N21/658 ,  G01N33/5308 ,  G01N33/553 ,  G01N2201/061 ,  G01N2201/0683

Abstract: A detection device (100) detects an analyte that may be contained in a specimen. The detection device (100) includes a plurality of gold nanoparticles, an optical trapping light source (101), an illumination light source (102), an objective lens (103), an image pick-up device (108), and a computation unit (106). The plurality of gold nanoparticles are each modified with a probe DNA allowing the analyte to specifically adhere thereto. The optical trapping light source (101) emits polarized light for assembling the plurality of gold nanoparticles together. The objective lens (103) focuses and introduces the polarized light into a liquid containing a specimen and the plurality of gold nanoparticles. The image pick-up device (108) receives light from the liquid. The computation unit (106) detects an analyte based on a signal received from the image pick-up device (108).

Abstract translation: 检测装置（100）检测可能包含在样本中的分析物。 检测装置（100）包括多个金纳米粒子，光俘获光源（101），照明光源（102），物镜（103），图像拾取装置（108）和计算机 单元（106）。 多个金纳米颗粒各自用允许分析物特异性粘附于其上的探针DNA修饰。 光俘获光源（101）发射用于将多个金纳米颗粒组装在一起的偏振光。 物镜（103）聚焦并将偏振光引入含有样本和多个金纳米颗粒的液体中。 图像拾取装置（108）接收来自液体的光。 计算单元（106）基于从图像拾取装置（108）接收的信号来检测分析物。

公开(公告)号：EP2980204A4

公开(公告)日：2016-10-19

申请号：EP14774943

申请日：2014-03-10

Applicant: SHARP KK ,  UNIV OSAKA PREFECT PUBLIC CORP

Inventor： IKEMIZU MUGIHEI ,  TOKONAMI SHIHO ,  SHIIGI HIROSHI ,  NAGAOKA TSUTOMU

IPC: C12M1/34 ,  C12Q1/04

CPC classification number: G01N33/5438 ,  C12M41/36 ,  C12Q1/04 ,  C25D5/34 ,  C25D5/48 ,  G01N33/569 ,  G01N2600/00