公开(公告)号：EP1592773A2

公开(公告)日：2005-11-09

申请号：EP04704892.1

申请日：2004-01-23

申请人： Avigenics Inc. ,  UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.

发明人： IVARIE, Robert, D. ,  HARVEY, Alex, J. ,  MORRIS, Julie, A. ,  LIU, Guodong ,  RAPP, Jeffrey, C.

IPC分类号： C12N1/00

CPC分类号： C12N15/86 ,  A01K2217/05 ,  A01K2227/30 ,  A01K2267/01 ,  C12N15/8509 ,  C12N15/902 ,  C12N2740/13043 ,  C12N2799/027 ,  C12N2830/008 ,  C12N2830/15 ,  C12N2830/40 ,  C12N2830/90 ,  C12N2840/20 ,  C12N2840/203

摘要： This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of avians in order to express the exogenous sequences to alter the phenotype of the avians or to produce desired proteins. In particular, transgenic avians are produced which express exogenous sequences in their oviducts and which deposit exogenous proteins into their eggs. Avian eggs that contain exogenous proteins are encompassed by this invention. The instant invention further provides novel forms of interferon and erythropoietin which are efficiently expressed in the oviduct of transgenic avians and deposited into avian eggs.

公开(公告)号：EP2007803A1

公开(公告)日：2008-12-31

申请号：EP07751151.7

申请日：2007-02-20

申请人： Avigenics, Inc. ,  University of Georgia Research Foundation, Inc.

发明人： IVARIE, Robert, D. ,  LIU, Guodong ,  RAPP, Jeffrey, C. ,  MORRIS, Julie, A. ,  HARVEY, Alex, J.

IPC分类号： C07K14/535

CPC分类号： C07K14/535

公开(公告)号：EP1023442A1

公开(公告)日：2000-08-02

申请号：EP98954994.4

申请日：1998-10-15

申请人： University of Georgia Research Foundation, Inc. ,  Avigenics

发明人： IVARIE, Robert, D. ,  HARVEY, Alex, J. ,  MORRIS, Julie, A. ,  LIU, Guodong

IPC分类号： C12N15/00 ,  A01K67/027 ,  C12N15/90

CPC分类号： C12N9/00 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2217/072 ,  A01K2227/30 ,  A01K2267/01 ,  A01K2267/025 ,  C07K14/77 ,  C07K16/00 ,  C12N15/8509 ,  C12N15/86 ,  C12N15/902 ,  C12N2740/11043 ,  C12N2799/027 ,  C12N2800/30 ,  C12N2800/90 ,  C12N2830/00 ,  C12N2830/008 ,  C12N2830/40 ,  C12N2830/42 ,  C12N2830/90 ,  C12N2840/20 ,  C12N2840/203 ,  C12N2840/44

摘要： This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of a bird and for expressing said exogenous sequences to alter the phenotype of the bird or to produce desired proteins. In particular, transgenic chickens are produced which express exogenous sequences in their oviducts. Eggs which contain exogenous proteins are also produced.

公开(公告)号：EP1023442B1

公开(公告)日：2010-11-24

申请号：EP98954994.4

申请日：1998-10-15

申请人： UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. ,  Synageva BioPharma Corp.

发明人： IVARIE, Robert, D. ,  HARVEY, Alex, J. ,  MORRIS, Julie, A. ,  LIU, Guodong ,  Rapp, Jeffrey C.

IPC分类号： C12N15/00 ,  A01K67/027 ,  C12N15/90

CPC分类号： C12N9/00 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2217/072 ,  A01K2227/30 ,  A01K2267/01 ,  A01K2267/025 ,  C07K14/77 ,  C07K16/00 ,  C12N15/8509 ,  C12N15/86 ,  C12N15/902 ,  C12N2740/11043 ,  C12N2799/027 ,  C12N2800/30 ,  C12N2800/90 ,  C12N2830/00 ,  C12N2830/008 ,  C12N2830/40 ,  C12N2830/42 ,  C12N2830/90 ,  C12N2840/20 ,  C12N2840/203 ,  C12N2840/44

摘要： This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of a bird and for expressing said exogenous sequences to alter the phenotype of the bird or to produce desired proteins. In particular, transgenic chickens are produced which express exogenous sequences in their oviducts. Eggs which contain exogenous proteins are also produced.