公开(公告)号：EP1161523A4

公开(公告)日：2003-04-02

申请号：EP00916410

申请日：2000-03-17

申请人： WELLSTAT BIOLOGICS CORP ,  US GOV HEALTH & HUMAN SERV

发明人： MAJOR EUGENE O ,  BARKER JEFFERY L ,  MARIC DRAGAN ,  RABIN HARVEY ,  SANDLER ABBY

IPC分类号： G01N33/50 ,  A61K35/12 ,  A61K35/30 ,  A61P25/00 ,  A61P25/16 ,  C12N5/0797 ,  C12N5/10 ,  C12Q1/04 ,  G01N33/15 ,  G01N33/53 ,  C12N5/06 ,  C12N5/08

CPC分类号： C12N5/0623 ,  A61K35/12 ,  C12N7/00 ,  C12N2510/00 ,  C12N2510/04 ,  C12N2710/22051

摘要： The present invention generally relates to stem cells, including progenitor and precursor cells, which are preferably immortalized, and have been derived from the central nervous system (CNS); methods for treating a host by implanting the disclosed cells, and genetically altered forms of the disclosed cells in the host, and methods for making same.

公开(公告)号：EP0832203A4

公开(公告)日：2002-07-17

申请号：EP96918000

申请日：1996-06-06

申请人： US GOV HEALTH & HUMAN SERV

发明人： MAJOR EUGENE O ,  TORNATORE CARLO S ,  YADID GAL

IPC分类号： C12N15/09 ,  A61K31/70 ,  A61K35/12 ,  A61K35/30 ,  A61K35/54 ,  A61K38/44 ,  A61K48/00 ,  A61P25/28 ,  C12N5/073 ,  C12N5/079 ,  C12N5/10 ,  C12N9/02 ,  C12N15/52 ,  C12N15/85 ,  C12N15/00

CPC分类号： C12N9/0071 ,  A61K35/30 ,  A61K35/54 ,  A61K38/00 ,  A61K48/00 ,  A61K2035/126 ,  C12N5/0622 ,  C12N15/85 ,  C12N2510/04 ,  C12N2800/108 ,  C12N2830/42 ,  C12Y114/13041 ,  C12Y114/16002

摘要： The present invention generally relates to methods for treating a host by implanting genetically unrelated cells in the host. More particularly, the present invention provides human fetal neuro-derived cell lines, and methods of treating a host by implantation of these immortalized human fetal neuro-derived cells into the host.