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    METHOD FOR DERIVING CORNEAL ENDOTHELIUM REPLACEMENT CELLS FROM IPS CELLS
    7.
    发明公开
    METHOD FOR DERIVING CORNEAL ENDOTHELIUM REPLACEMENT CELLS FROM IPS CELLS 审中-公开

    公开(公告)号：EP3741844A1

    公开(公告)日：2020-11-25

    申请号：EP19741620.9

    申请日：2019-01-16

    申请人： Keio University

    发明人： SHIMMURA, Shigeto ,  HATOU, Shin ,  TSUBOTA, Kazuo

    IPC分类号： C12N5/0793 ,  A61K35/30 ,  A61L27/38 ,  A61P27/02 ,  C12N5/00 ,  C12N5/0735 ,  C12N5/10

    摘要： Using the medium of the present invention for inducing a cornea endothelial substitute cell from an iPS cell, the medium containing an insulin-like growth factor and a STAT3 activator, and not containing a basic fibroblast growth factor or a ROCK inhibitor, and the method of the present invention for inducing corneal endothelial substitute cells from iPS cells by using the medium, it becomes possible to efficiently produce corneal endothelial substitute cells, particularly to efficiently produce corneal endothelial substitute cells from iPS cells. Furthermore, it becomes possible to stably produce large amounts of corneal endothelial substitute cells by inducing differentiation of iPS cells into corneal endothelial substitute cells more efficiently.

    BRAIN WAVE ASSESSMENT SYSTEM, BRAIN WAVE ASSESSMENT METHOD, PROGRAM, AND NON-TRANSIENT RECORDING MEDIUM
    8.
    发明公开
    BRAIN WAVE ASSESSMENT SYSTEM, BRAIN WAVE ASSESSMENT METHOD, PROGRAM, AND NON-TRANSIENT RECORDING MEDIUM 审中-公开

    公开(公告)号：EP3698712A1

    公开(公告)日：2020-08-26

    申请号：EP18868564.8

    申请日：2018-10-19

    申请人： Panasonic Corporation ,  Keio University

    发明人： USHIBA, Junichi ,  MORIKAWA, Koji

    IPC分类号： A61B5/0476 ,  A61H1/02 ,  G06F3/01

    摘要： An object is to improve the decision accuracy of electroencephalograms. An electroencephalogram decision system (10) determines, when finding electroencephalogram information representing an electroencephalogram obtained by an electrode unit (11) placed on a region of interest that forms part of a subject's (5) head (52) satisfying a predetermined condition, that a target electroencephalogram, which is an electroencephalogram with a characteristic variation, should have been produced. The predetermined condition is selected from a plurality of detection conditions including a first type of condition and a second type of condition. The first type of condition specifies that a decision should be made, based on a component falling within a single frequency band included in the electroencephalogram represented by the electroencephalogram information, whether or not the target electroencephalogram has been produced. The second type of condition specifies that a decision should be made, based on components falling within multiple different frequency bands included in the electroencephalogram represented by the electroencephalogram information, whether or not the target electroencephalogram has been produced.