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    WATER-BASED ADHESIVE SKIN PATCH COMPRISING KETOPROFEN LYSINE SALT
    4.
    发明授权
    WATER-BASED ADHESIVE SKIN PATCH COMPRISING KETOPROFEN LYSINE SALT 有权

    公开(公告)号：EP2266556B1

    公开(公告)日：2018-11-14

    申请号：EP09724708.4

    申请日：2009-03-24

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： INAZUKI, Masahiro

    IPC分类号： A61K31/192 ,  A61K9/70 ,  A61K47/02 ,  A61K47/10 ,  A61K47/30 ,  A61P29/00

    CPC分类号： A61K31/192 ,  A61K9/7061 ,  A61K47/10

    摘要： A ketoprofen-containing aqueous patch is provided in which not only operational efficiency in producing is improved, but also the aqueous patch has excellent storage stability and transdermal absorption of ketoprofen. The ketoprofen lysine salt-containing aqueous patch includes a backing layer and an adhesive (paste) layer laminated thereon. The aqueous patch includes as a main active ingredient a ketoprofen lysine salt completely dissolved in a paste including not glycerin but a polyethylene glycol having an average molecular weight of 1000 or less. In the ketoprofen lysine salt-containing aqueous patch, the polyethylene glycol having an average molecular weight of 1000 or less is one or more polyethylene glycols selected from the group consisting of Polyethylene glycol 200, Polyethylene glycol 400, Polyethylene glycol 600, and Polyethylene glycol 1000.

    RECEIVING CONTAINER
    5.
    发明公开
    RECEIVING CONTAINER 审中-公开

    公开(公告)号：EP3339203A1

    公开(公告)日：2018-06-27

    申请号：EP16836871.0

    申请日：2016-06-22

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： UEMATSU, Masanori

    IPC分类号： B65D5/66 ,  B65D5/475 ,  B65D5/54

    CPC分类号： B65D5/541 ,  B65D5/46024 ,  B65D5/6602

    摘要： A receiving container includes a container body 4 and a grip member 5. The container body 4 includes: a body portion 1 in a hollow tubular shape; a bottom portion 2 configured to close one end side opening portion of the body portion 1; and a ceiling portion 3 configured to close another end side opening portion of the body portion 1. The ceiling portion 3 includes a first extending portion 17d and a second extending portion 17b extending from an edge of the other end side opening portion. One of the first extending portion 17d and the second extending portion 17b is provided with a separation portion 25 configured to separate a tip portion. The grip member 5 includes: attachment portions 31, and a grip portion 30 grippable by hand. The attachment portions 31 are configured to prevent the first extending portion 17d and the second extending portion 17b from opening from the other end side opening portion. The attachment portions 31 are attached to a tip side of the separation portion 25 in either of the first or second extending portion 17d or 17b provided with the separation portion 25.

    TRANSDERMAL PREPARATION
    7.
    发明公开
    TRANSDERMAL PREPARATION 审中-公开
    TRANSDERMALESPRÄPARAT

    公开(公告)号：EP3150205A1

    公开(公告)日：2017-04-05

    申请号：EP15800275.8

    申请日：2015-05-20

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： KAWAKAMI, Satoshi ,  SHIBATA, Taiki ,  SOGABE, Manabu

    IPC分类号： A61K31/404 ,  A61K9/70 ,  A61K31/18 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34 ,  A61P13/12 ,  A61P43/00

    CPC分类号： A61K31/18 ,  A61K9/70 ,  A61K9/7061 ,  A61K31/404 ,  A61K47/10 ,  A61K47/32 ,  A61K47/34

    摘要： Provided is a novel transdermal absorption preparation containing silodosin or tamsulosin, or salt thereof as an active ingredient, wherein the transdermal absorption preparation is capable of keeping a dissolved state for a long time, as well as has a high permeability to a skin, and can effectively and sustainably exert the transdermal absorbability. A transdermal absorption preparation containing the transdermal absorption preparation comprises an acrylic pressure-sensitive adhesive that comprises a copolymer of at least one (meth)acrylic acid monomer and at least one vinyl monomer and that contains a carboxyl group, and at least one transdermal absorption promoting agent selected from the group consisting of oleyl alcohol, lauryl alcohol, and lauromacrogol.

    摘要翻译： 本发明提供一种含有西洛多辛或坦索罗辛或其盐作为活性成分的新型透皮吸收制剂，其中经皮吸收制剂能够长期保持溶解状态，并且具有对皮肤的高渗透性，并且可以 有效和可持续地发挥经皮吸收能力。 含有透皮吸收制剂的透皮吸收制剂包括丙烯酸类压敏粘合剂，其包含至少一种（甲基）丙烯酸单体和至少一种乙烯基单体并且含有羧基的共聚物，以及至少一种透皮吸收促进剂 选自油醇，月桂醇和月桂醇的组合物。

    FELBINAC-CONTAINING EXTERNAL PATCH
    10.
    发明公开
    FELBINAC-CONTAINING EXTERNAL PATCH 有权
    FELBINAC-包含外部补丁

    公开(公告)号：EP2636405A1

    公开(公告)日：2013-09-11

    申请号：EP11838026.0

    申请日：2011-11-01

    申请人： Teikoku Seiyaku Co., Ltd.

    发明人： INOO, Katsuyuki

    IPC分类号： A61K31/192 ,  A61K9/70 ,  A61K47/14 ,  A61K47/32 ,  A61P29/00

    CPC分类号： A61K9/7007 ,  A61K9/7053 ,  A61K31/192

    摘要： Provided is a felbinac-containing external patch which can exhibit high drug release properties, low skin irritation, and high drug stability, wherein felbinac having an average particle diameter of 5 µm or more and less than 100 µm is dispersed and mixed in an adhesive base including a styrene-isoprene-styrene block copolymer, an alicyclic saturated hydrocarbon resin, a softener, and diethyl sebacate, and does not contain L-menthol. Specifically, in the felbinac-containing external patch, 0.1 to 10% by weight of felbinac having an average particle diameter of 5 µm or more and less than 100 µm is dispersed and mixed in an adhesive base including 10 to 30% by weight of a styrene-isoprene-styrene block copolymer, 10 to 50% by weight of an alicyclic saturated hydrocarbon resin, 10 to 75% by weight of a softener, and 0.1 to 10% by weight of diethyl sebacate.

    摘要翻译： 本发明提供一种含有联苯乙酸的外用贴剂，其能够表现出高的药物释放性，低皮肤刺激性和高药物稳定性，其中平均粒径为5μm以上且小于100μm的联苯乙酸克分散和混合在粘合剂基质 包括苯乙烯 - 异戊二烯 - 苯乙烯嵌段共聚物，脂环族饱和烃树脂，软化剂和癸二酸二乙酯，并且不含L-薄荷醇。 具体而言，在含有联苯乙酸的外用贴剂中，将平均粒径5μm以上且小于100μm的联苯乙酰乙酸0.1〜10重量％分散混合到含有10〜30重量％ 苯乙烯 - 异戊二烯 - 苯乙烯嵌段共聚物，10〜50重量％的脂环族饱和烃树脂，10〜75重量％的软化剂和0.1〜10重量％的癸二酸二乙酯。