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公开(公告)号:EP4433494A2
公开(公告)日:2024-09-25
申请号:EP22839929.1
申请日:2022-11-18
发明人: KMIEC, Eric B. , YOO, Byung-chun , YANG, Steven , BANAS, Kelly H.
IPC分类号: C07K14/475 , A61K31/7105 , A61K48/00 , C12N9/22
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公开(公告)号:EP3978031B1
公开(公告)日:2024-07-17
申请号:EP21198809.2
申请日:2015-08-04
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公开(公告)号:EP4388105A1
公开(公告)日:2024-06-26
申请号:EP22859320.8
申请日:2022-08-16
IPC分类号: C12N15/55 , C12N15/09 , C12N15/52 , C12N15/90 , C12N5/0783
CPC分类号: A01K2207/1520130101 , A01K2207/1220130101 , A01K2227/10520130101 , A01K2267/0320130101 , C12N2320/1120130101 , C12N2310/2020170501 , C12N15/1138 , C12N15/63 , C12N15/1034 , C12N5/0636 , C12N2510/0020130101 , C12N2501/230720130101 , C12N2501/231520130101 , A61K39/4611 , A61K39/4631 , A61P35/00 , A61K39/4644 , C07K14/70539 , C07K14/55 , C07K14/4717 , C07K2319/0220130101 , C07K2319/0320130101 , C07K14/7051 , A61K39/4613 , A61K2239/2620230501 , A61K39/464411 , A61K2239/3820230501
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公开(公告)号:EP4371584A2
公开(公告)日:2024-05-22
申请号:EP23215104.3
申请日:2017-12-21
IPC分类号: A61L27/24
CPC分类号: A61K9/0024 , A61K47/36 , A61K47/6901 , A61L27/06 , A61L27/18 , A61L27/225 , A61L27/3804 , A61L27/54 , A61L2300/25620130101 , A61L2300/42620130101 , A61L2300/43220130101 , A61P35/00 , A61P35/04 , C12N5/0636 , C07K14/7051 , C12N2740/1504320130101 , A61P1/18 , C07K2319/0320130101 , C07K2319/3320130101 , C07K2319/7420130101 , C07K14/7056 , A61K2039/5556120130101 , C07K16/2809 , C07K16/2818 , C07K16/2878 , C07K2317/5320130101 , C07K2317/7520130101 , A01K2207/1220130101 , A61L31/16 , A61L31/10 , C12N2510/0020130101 , C12N2513/0020130101 , C12N2533/5620130101 , C12N2535/0020130101 , A61K39/4611 , C12N5/0638 , A61K39/464429 , A61K39/4631 , A61K2239/3120230501 , A61K2239/5420230501
摘要: Implantable scaffolds that treat solid tumors and escape variants and that provide effective vaccinations against cancer recurrence are described. The scaffolds include genetically-reprogrammed lymphocytes and a lymphocyte-activating moiety.
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公开(公告)号:EP4268831A3
公开(公告)日:2024-05-22
申请号:EP23181499.7
申请日:2019-09-12
IPC分类号: C12N15/113 , A61K31/713
CPC分类号: A61K38/00 , A61K35/28 , C12N15/1138 , C12N2310/1420130101 , C12N2310/53120130101 , C12N2740/1604320130101 , A01K2227/10520130101 , A01K2207/1220130101 , A61K47/6849
摘要: Systems and methods to selectively protect therapeutic cells by reducing CD33 expression in the therapeutic cells and targeting non-therapeutic cells with an anti-CD33 therapy. The selective protection results in the enrichment of the therapeutic cells while simultaneously targeting any diseased, malignant and/or non-therapeutic CD33 expressing cells within a subject.
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公开(公告)号:EP4441206A2
公开(公告)日:2024-10-09
申请号:EP22901932.8
申请日:2022-11-30
发明人: SINGHAL, Amit , DILIP, Kumar
IPC分类号: C12N5/16 , C12N15/00 , C12N15/113 , G01N33/50 , A61P35/02
CPC分类号: A01K67/0271 , A01K2207/1520130101 , A01K2207/1220130101 , A01K2217/07520130101 , A01K2217/1520130101 , A01K2227/10520130101 , A01K2267/033120130101 , C12N15/113 , C12N2740/1604320130101 , G01N33/5011 , C12N2310/2020170501 , C12N2320/1220130101 , C12N15/1137 , C12N2310/1420130101 , C12Y306/03014
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公开(公告)号:EP4430199A2
公开(公告)日:2024-09-18
申请号:EP22840839.9
申请日:2022-11-23
发明人: CASSADY, Kevin A.
IPC分类号: C12N15/86 , A61K35/763 , A61K38/20
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公开(公告)号:EP4422634A2
公开(公告)日:2024-09-04
申请号:EP22812555.5
申请日:2022-10-27
申请人: Association Institut de Myologie , SORBONNE UNIVERSITE , Institut National de la Santé et de la Recherche Médicale (INSERM)
IPC分类号: A61K31/506 , A61K31/00 , A61K31/36 , A61K31/4025 , A61K31/405 , A61K31/422 , A61K31/496 , A61K31/505 , A61K45/06 , A61K48/00 , A61P21/00 , G01N33/74 , G01N33/68 , A01K67/027
CPC分类号: A61K31/506 , A61K31/4025 , A61K31/505 , A61K31/422 , A61K31/496 , A61K31/36 , A61K31/405 , A61K31/00 , A61K45/06 , G01N33/74 , A61P21/00 , G01N2333/575420130101 , G01N33/6893 , G01N2800/5220130101 , G01N2800/705220130101 , A01K67/0271 , A01K2207/1220130101 , A01K2207/1520130101
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9.
公开(公告)号:EP4419655A1
公开(公告)日:2024-08-28
申请号:EP22802421.2
申请日:2022-10-08
IPC分类号: C12N5/079 , A01K67/027 , A61K35/30
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公开(公告)号:EP3638304B1
公开(公告)日:2024-07-31
申请号:EP18818114.3
申请日:2018-06-11
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