公开(公告)号：EP3128916A4

公开(公告)日：2018-01-03

申请号：EP15776457

申请日：2015-04-02

申请人： FAUBERT JOCELYN ,  DOTI RAFAEL ,  LUGO-ARCE JESUS-EDUARDO

发明人： FAUBERT JOCELYN ,  DOTI RAFAEL ,  LUGO-ARCE JESUS-EDUARDO

IPC分类号： A61B5/16 ,  A61B3/02 ,  A61B3/10 ,  A61B5/00 ,  A61B5/01 ,  A61B5/11 ,  A61B5/12 ,  A61B9/00

CPC分类号： A61B5/162 ,  A61B3/02 ,  A61B5/0051 ,  A61B5/01 ,  A61B5/1124 ,  A61B5/123 ,  A61B5/125 ,  A61B5/4005 ,  A61B5/4011 ,  A61B5/4017 ,  A61B5/483 ,  A61B5/486 ,  A61B5/7225 ,  A61B5/7455 ,  A61B2560/0223

摘要： A configurable system is used to evaluate stimulus sensitivity of a subject. An action channel provides a stimulus to the subject and a reaction channel receives a response from the subject. A signal pathway is connected to the action channel and to the reaction channel. A controller establishes loops within the signal pathway. Loop types include a transduction loop including the action channel and forming a path terminating in the signal pathway, and a channel loop including the action channel and terminating at a reference unit. Other possible loop types include an interface loop including the action channel, the reaction channel and the reference unit having an initial parameter value, and an adaptive loop including the action channel, the reaction channel and the reference unit whose parameter value is adapted based on the response from the subject. A method using the system is also described.

公开(公告)号：EP3056939A1

公开(公告)日：2016-08-17

申请号：EP14852733.6

申请日：2014-10-06

申请人： Tokai Optical Co., Ltd. ,  Inter-University Research Institute Corporation National Institutes of Natural Sciences

发明人： SUZUKI Masaya ,  KUMAGAI Naoya ,  INUI Koji ,  TAKESHIMA Yasuyuki ,  KAKIGI Ryusuke

IPC分类号： G02C13/00 ,  A61B3/10 ,  A61B5/0484 ,  G02C7/02 ,  G02C7/06

CPC分类号： A61B5/04842 ,  A61B3/0025 ,  A61B3/036 ,  A61B3/08 ,  A61B5/04008 ,  A61B5/04009 ,  A61B5/04012 ,  A61B5/4005 ,  A61B5/7257 ,  A61B2562/0223 ,  G02C7/027 ,  G02C7/028 ,  G02C7/061

摘要： [Problem] The invention provides an evaluation method capable of objectively evaluating average visual perception for a comparatively long period of time when a subject looks through an eyeglass lens to be evaluated, time-dependent change in visual perception, and visual perception when looking with both eyes, and the invention provides a design method, and the invention provides a calculation method for calculating characteristics of visual perception of the subject when viewing an object through a lens.
[Solution] A subject is allowed to wear a lens to be evaluated, the subject is allowed to induce brain activity by allowing the subject to view a changing visual stimulus object that induces periodic brain activity through the lens to be evaluated, a change in faint electric current caused by the brain activity is time-dependently recorded as a change in a magnetic field (magnetic flux density) by use of a magnetoencephalograph, one or more among an amplitude, a power value, and a phase in a frequency that is an inverse number of a period of the periodic brain activity is or are calculated through fast Fourier analysis of the waveform, and the lens to be evaluated and the characteristic of visual perception of the subject are evaluated based on a magnitude of an amplitude or of a power value obtained above or based on a slowness/fastness of a phase obtained above.

公开(公告)号：EP2572637A4

公开(公告)日：2013-11-06

申请号：EP11783689

申请日：2011-04-15

申请人： PARK JONG-EUN

发明人： PARK JONG-EUN

IPC分类号： A61B5/0482 ,  A41D19/00 ,  A43B7/14 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/0484 ,  A61B5/11 ,  A61B5/1455

CPC分类号： A61B5/4005 ,  A43B3/0015 ,  A43B7/025 ,  A43B7/146 ,  A43B7/147 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/026 ,  A61B5/14551 ,  A61B5/4047 ,  A61B5/4827 ,  A61B5/483 ,  A61B5/6804 ,  A61B5/6806 ,  A61B5/6807 ,  A61B5/6825 ,  A61B5/6829

摘要： The present invention relates to a device for examining nerve function. In order to examine the function of a nerve of the human body, the device for examining nerve function of the present invention includes: at least one stimulator for stimulating the human body; and a stimulator-fixing member having a form corresponding to the hands or feet of the human body, wherein the stimulator is located at one side of the simulator-fixing member so as to fix the stimulator to the hands or feet of the human body. The device for examining nerve function of the present invention further includes at least one blood-circulation detection sensor fixed at the stimulator-fixing member. According to the present invention, since the degree of hypoesthesia is examined through the stimulation of the stimulator, test accuracy and reliability may be greatly improved and it is possible to systematically and actively determine a diagnosis and course of treatment for a patient having diabetes or spinal nerve damage, e.g. hypoesthesia.

公开(公告)号：EP4408272A1

公开(公告)日：2024-08-07

申请号：EP22873714.4

申请日：2022-09-26

申请人： Cognito Therapeutics, Inc.

发明人： MALCHANO, Zachary ,  VAUGHAN, Brent ,  WILLIAMS, Martin ,  HAJOS, Mihaly ,  BOYDEN, Edward ,  CIMENSER, Aylin ,  DA, Xiao

IPC分类号： A61B5/05 ,  A61B5/055 ,  A61B5/16 ,  A61B5/38 ,  G16H20/00 ,  G16H40/60 ,  A61B5/00 ,  A61B5/024 ,  A61B5/369 ,  A61B5/378 ,  A61B5/398 ,  A61N5/06 ,  G06F3/01

CPC分类号： A61N5/0622 ,  A61B5/4005 ,  A61B5/055 ,  A61B5/4064 ,  A61B5/01 ,  A61B5/024 ,  A61B5/021 ,  A61B5/375 ,  A61B5/37 ,  A61B5/378 ,  A61B5/38 ,  A61B5/4812 ,  A61B5/4815 ,  A61B5/4836 ,  A61B5/0042 ,  A61N2005/065120130101 ,  A61N2005/066220130101 ,  A61N2005/064220130101 ,  A61N2005/062620130101 ,  A61N2005/064820130101 ,  A61N2005/065920130101 ,  A61N2005/066120130101 ,  A61N2005/066320130101 ,  A61N5/0618

公开(公告)号：EP3609386B1

公开(公告)日：2024-06-05

申请号：EP18721476.2

申请日：2018-04-12

IPC分类号： A61B5/00 ,  A61M21/00

CPC分类号： A61B5/6843 ,  A61B5/0053 ,  A61B5/4005 ,  A61B5/4029 ,  A61B2562/024720130101 ,  A61B2562/04320130101

公开(公告)号：EP1691766A2

公开(公告)日：2006-08-23

申请号：EP04817912.1

申请日：2004-11-26

申请人： Tyler, Mitchell Eugene ,  Danilov, Yuri Petrovich ,  Bach-y-Rita, Paul

发明人： Tyler, Mitchell Eugene ,  Danilov, Yuri Petrovich ,  Bach-y-Rita, Paul

IPC分类号： A61K6/00

CPC分类号： A61M21/00 ,  A61B5/0492 ,  A61B5/11 ,  A61B5/1116 ,  A61B5/112 ,  A61B5/1123 ,  A61B5/1124 ,  A61B5/4005 ,  A61B5/4023 ,  A61B5/4519 ,  A61B5/4528 ,  A61B5/486 ,  A61B5/682 ,  A61B5/7225 ,  A61B5/726 ,  A61B2562/0209 ,  A61B2562/046 ,  A61F9/08 ,  A61F11/00 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0044 ,  A61M2210/0643 ,  A61N1/36014 ,  A61N1/36025 ,  A61N1/36082 ,  A61N1/36103 ,  G06F3/015

摘要： The present invention relates to systems and methods for management of brain and body functions and sensory perception. For example, the present invention provides systems and methods of sensory substitution and sensory enhancement (augmentation) as well as motor control enhancement. The present invention also provides systems and methods of treating diseases and conditions, as well as providing enhanced physical and mental health and performance through sensory substitution, sensory enhancement, and related effects. In particular, the present invention provides systems and methods for altering vestibular biology to, among other things, treat diseases and conditions or enhance performance related to vestibular functions.

公开(公告)号：EP3338624A1

公开(公告)日：2018-06-27

申请号：EP16206649.2

申请日：2016-12-23

申请人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)

发明人： BLANKE, Olaf ,  ROGNINI, Giulio

IPC分类号： A61B5/00 ,  B25J3/04

CPC分类号： A61B5/7275 ,  A61B5/16 ,  A61B5/4005 ,  A61B5/4064 ,  A61B5/4082 ,  A61N1/36082 ,  B25J3/04 ,  B25J9/1689 ,  B25J13/025

摘要： A robotic system and associated method for predicting the likelihood of occurrence of hallucinations in a subject is disclosed. The system comprises a robotic master-slave device and computer means adapted to induce conflicting sensorimotor stimulations to a subject for inducing the feeling of a presence. Comparing subjective response data, combined with data related to the movement of the master-slave device, with reference data, allows to predict the likelihood of occurrence of hallucinations in a tested subject. The system and the method for using thereof can find applications in Parkinson's Disease patients for the prognostic evaluation of psychiatric-associated symptoms.

公开(公告)号：EP2868270B1

公开(公告)日：2018-05-09

申请号：EP14191554.6

申请日：2014-11-03

申请人： Seiko Instruments Inc. ,  Nihon Kohden Corporation

发明人： Sugawara, Ryo ,  Kobayashi, Tomoo ,  Motogi, Jun

IPC分类号： A61B5/05 ,  A61N1/04 ,  A61B5/00

CPC分类号： A61N1/0456 ,  A61B5/05 ,  A61B5/4005 ,  A61B5/4047 ,  A61N1/0476 ,  A61N1/0488 ,  H05K3/306 ,  Y10T29/49133

摘要： Provided are a living body stimulating electrode, a living body stimulating electrode apparatus, and a method for producing a living body stimulating electrode. The living body stimulating electrode has a flexible circuit board (FPC) between a living body stimulating electrode and a resin part. The resin part and the FPC are fixed with the living body stimulating electrode. Specifically, the flexible circuit board is disposed between the living body stimulating electrode and the resin part, and one or both of a stimulating electrode and a contact electrode constituting the living body stimulating electrode have an engaging part having a pressing part and a fixing part. The pressing part presses the flexible circuit board onto the resin part. Simultaneously, the fixing part is penetrated through a through hole formed in the flexible circuit board and pressed into a hole formed in the resin part, thereby fixed to and held by the resin part. The engaging part may be subjected to a chamfering process (the edge may be chamfered into an angulated plane or a round plane) to form an inclined plane or a curved (round) plane.

公开(公告)号：EP2898834A1

公开(公告)日：2015-07-29

申请号：EP12884846.2

申请日：2012-09-18

申请人： National Institute of Advanced Industrial Science and Technology ,  Showa University ,  Asuka Electric Co. Ltd. ,  Takahashi, Noriyo

发明人： INO, Shuichi ,  SATO, Mitsuru ,  TAKAHASHI, Noriyo ,  YOSHIMURA, Shinichi

IPC分类号： A61B10/00

CPC分类号： A61B5/4076 ,  A61B5/0051 ,  A61B5/4005 ,  A61B5/4029 ,  A61B5/4827 ,  A61B5/6829 ,  A61B5/742 ,  F04C2270/041

摘要： [Problem]
To provide an apparatus for measuring a sensory threshold at the time of application of a moving stimulus to a sole simply with high reproducibility and evaluating peripheral neuropathy originating in diabetes.
[Solution]
Provided are a foot pedestal 2, a probe 4 for applying a moving stimulus to a sole, and a probe driving structure 3, disposed on a base 1, for operating the probe 4 to separately move in directions intersecting at right angles along the sole. Also provided are an input switch 5 to be operated by a subject recognizing a moving stimulus, a drive controller 51 for controlling drive condition of the probe driving structure 3, and a main controller B for evaluating a measured sensory threshold. The main controller B preliminarily stores reference data of known sensory thresholds obtained by applying a moving stimulus to a sole of patients, and age correction factors calculated from standard values of sensory thresholds based on different ages of patients. The drive controller 51 controls drive condition of the probe driving structure 3 by using the reference data and the age correction factors to conduct a primary stimulus applying condition. Further, a secondary stimulus applying condition, and a tertiary stimulus applying condition are sequentially conducted to measure a sensory threshold.

摘要翻译： [问题]提供一种用于在将运动刺激应用于鞋底时简单地以高再现性测量感觉阈值并评估源于糖尿病的周围神经病变的装置。 [解决方案]设置有脚踏座2，用于向鞋底施加移动刺激的探针4和设置在基座1上的探针驱动结构3，用于操作探针4以沿直角相交的方向分开移动 唯一的。 还提供了由被识别移动刺激的被摄体操作的输入开关5，用于控制探针驱动结构3的驱动条件的驱动控制器51和用于评估测量的感觉阈值的主控制器B. 主控制器B预先存储通过将运动刺激应用于患者唯一而获得的已知感觉阈值的参考数据，以及基于患者不同年龄的感觉阈值的标准值计算的年龄校正因子。 驱动控制器51通过使用参考数据和年龄校正因子来控制探针驱动结构3的驱动条件以进行主刺激施加条件。 此外，依次进行二次刺激施加条件和三次刺激施加条件以测量感觉阈值。

公开(公告)号：EP2868270A1

公开(公告)日：2015-05-06

申请号：EP14191554.6

申请日：2014-11-03

申请人： Seiko Instruments Inc. ,  Nihon Kohden Corporation

发明人： Sugawara, Ryo ,  Kobayashi, Tomoo ,  Motogi, Jun

IPC分类号： A61B5/05 ,  A61N1/04 ,  A61B5/00

CPC分类号： A61N1/0456 ,  A61B5/05 ,  A61B5/4005 ,  A61B5/4047 ,  A61N1/0476 ,  A61N1/0488 ,  H05K3/306 ,  Y10T29/49133

摘要： Provided are a living body stimulating electrode, a living body stimulating electrode apparatus, and a method for producing a living body stimulating electrode. The living body stimulating electrode has a flexible circuit board (FPC) between a living body stimulating electrode and a resin part. The resin part and the FPC are fixed with the living body stimulating electrode. Specifically, the flexible circuit board is disposed between the living body stimulating electrode and the resin part, and one or both of a stimulating electrode and a contact electrode constituting the living body stimulating electrode have an engaging part having a pressing part and a fixing part. The pressing part presses the flexible circuit board onto the resin part. Simultaneously, the fixing part is penetrated through a through hole formed in the flexible circuit board and pressed into a hole formed in the resin part, thereby fixed to and held by the resin part. The engaging part may be subjected to a chamfering process (the edge may be chamfered into an angulated plane or a round plane) to form an inclined plane or a curved (round) plane.

摘要翻译： 本发明提供一种活体刺激电极，活体刺激电极装置，以及一种用于制造活体刺激电极的方法。 活体刺激电极具有活体刺激电极和一个树脂部分之间的柔性电路板（FPC）。 树脂部和FPC固定与所述活体刺激电极。 具体地，该柔性电路板被活体刺激电极和树脂部，和一个或两个刺激电极的和构成活体刺激电极的接触电极之间设置有具有按压部和固定部的卡合部。 按压部按压所述柔性电路板到树脂部分。 同时，固定部通过设置在柔性电路板形成，并且被压入在所述树脂部件形成的孔的通孔穿透，从而固定并通过树脂部保持。 接合部可以经过倒角加工（该边缘可以在角形或圆形平面被倒角成规划），以形成上倾斜平面或弯曲的（圆）面。