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1.发明公开METHOD AND APPARATUS FOR DERMATOLOGICAL HYPOPIGMENTATION 审中-公开VERFAHREN UND VORRICHTUNGFÜRDERMATOLOGISCHE HYPOPIGMENTIERUNG
公开(公告)号：EP2320840A2
公开(公告)日：2011-05-18
申请号：EP09805610.4
申请日：2009-08-07
CPC分类号： A61B18/0218 , A61B2017/00747 , A61B2018/00005 , A61B2018/00458 , A61B2018/0047 , A61B2018/00577 , A61B2018/00714 , A61B2018/00815 , A61B2018/00821 , A61B2018/0237 , A61B2018/0293 , A61B2018/143 , A61F7/00 , A61F7/0085 , A61F7/10 , A61F2007/0052 , A61F2007/0056 , A61F2007/0063 , A61F2007/0075 , A61F2007/0086 , A61F2007/0087 , A61F2007/0089 , A61F2007/0095 , A61F2007/0096 , A61F2007/0292
摘要： Exemplary embodiments of the present disclosure provide method and apparatus for effecting (e.g., lightening) an appearance of skin by cooling or freezing small separated surface regions of the skin to produce regions of local hypopigmentation. The width of the regions can be, for example, smaller than about 1 mm or 0.5 mm, and a distance between these frozen regions can be greater than about 3 times the width of the regions. An exemplary apparatus can be provided that includes a plurality of spatially-separated thermally conductive arrangements that can be affixed or otherwise coupled to a base. For example, the conductive arrangements can be regions of conductive material provided in or proximal to a thermal insulator, or thermally conductive protrusions affixed to the base. The conductive arrangements can be cooled and then contacted with the skin surface to produce the small regions of hypopigmentation.
摘要翻译： 本公开的示例性实施方案提供了通过冷却或冷冻皮肤的小分离表面区域来实现（例如，减轻）皮肤外观的方法和装置，以产生局部色素沉着的区域。 区域的宽度可以例如小于约1mm或0.5mm，并且这些冻结区域之间的距离可以大于区域宽度的约3倍。 可以提供一种示例性装置，其包括可以固定或以其他方式耦合到基座的多个空间分离的导热装置。 例如，导电布置可以是设置在绝热体中或靠近绝热体的导电材料的区域，或者固定到基底的导热突起。 导电布置可以被冷却，然后与皮肤表面接触以产生色素减少的小区域。
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公开(公告)号：EP3470828A2
公开(公告)日：2019-04-17
申请号：EP18400013.1
申请日：2018-05-28
CPC分类号： G01R33/383 , A61B5/055 , A61B18/06 , A61B18/1815 , A61B34/30 , A61B90/37 , A61B2017/320069 , A61B2018/00577 , A61B2018/00994 , A61B2090/374 , A61F2/82 , A61F7/00 , A61F2007/0089 , A61F2007/009 , A61F2250/0001 , A61K31/714 , A61K33/24 , A61N2/002 , A61N2/06 , A61N7/02 , G01N24/10 , G01N24/12 , G01N24/14 , G01R33/282 , G01R33/285 , G01R33/307 , G01R33/32 , G01R33/323 , G01R33/3621 , G01R33/3802 , G01R33/3808 , G01R33/3873 , G01R33/465 , G01R33/48 , G01R33/4804 , G01R33/56308 , G01R33/60 , H01F1/0557 , H01F41/0273 , H03F3/54
摘要： The invention pertains to advances in real-time methods in nuclear magnetic resonance by offering:
• a new real-time processing method for nuclear magnetic resonance (NMR) spectrum acquisition without external resonator(s), which remains stable despite magnetic field fluctuations,
• a new processing method for nuclear magnetic resonance spectrum acquisition, which remains stable despite magnetic field fluctuations and resonator stability,
• a new method of constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region,
• a new dual frequency dynamic nuclear polarization (DNP) generator that polarizes the spin of electrons and acts as an NMR transmitter.-
公开(公告)号：EP1697003A2
公开(公告)日：2006-09-06
申请号：EP04800624.1
申请日：2004-11-03
IPC分类号： A61N5/06
CPC分类号： A46B15/0036 , A46B7/10 , A46B13/023 , A46B15/0002 , A46B2200/102 , A61B18/203 , A61B18/28 , A61B2017/00057 , A61B2017/00084 , A61B2018/00005 , A61B2018/00029 , A61B2018/00452 , A61B2018/206 , A61B2090/065 , A61F7/00 , A61F2007/0087 , A61F2007/0089 , A61F2007/0096 , A61F2007/0292 , A61F2007/108 , A61N5/0601 , A61N5/0616 , A61N5/0617 , A61N5/062 , A61N2005/005 , A61N2005/0606 , A61N2005/0644 , A61N2005/0652 , A61N2005/0668
摘要： An apparatus is disclosed that uses at least one low power optical radiation source in a suitable head which can be held over a treatment area for a substantial period of time or can be moved over the treatment area a number of times during each treatment. The apparatus, a hand held light emitting applicator (LEA) or light emitting skin applicator (LESA), can be in the form of a brush or roller adapted to be moved over the patient's skin surface as radiation is applied to the skin. The skin-contacting surface of the LEA or LESA can have protuberances such as projections or bristles that can massage the skin and deliver radiation. In addition, an apparatus which delivers optical radiation to a treatment area is disclosed that contains a retrofit housing adapted to be joined to a skin-contacting device.
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4.发明公开
公开(公告)号：EP3495806A2
公开(公告)日：2019-06-12
申请号：EP18400012.3
申请日：2018-05-28
CPC分类号： G01R33/383 , A61B5/055 , A61B18/06 , A61B18/1815 , A61B34/30 , A61B90/37 , A61B2017/320069 , A61B2018/00577 , A61B2018/00994 , A61B2090/374 , A61F2/82 , A61F7/00 , A61F2007/0089 , A61F2007/009 , A61F2250/0001 , A61K31/714 , A61K33/24 , A61N2/002 , A61N2/06 , A61N7/02 , G01N24/10 , G01N24/12 , G01N24/14 , G01R33/282 , G01R33/285 , G01R33/307 , G01R33/32 , G01R33/323 , G01R33/3621 , G01R33/3802 , G01R33/3808 , G01R33/3873 , G01R33/465 , G01R33/48 , G01R33/4804 , G01R33/56308 , G01R33/60 , H01F1/0557 , H01F41/0273 , H03F3/54
摘要： The invention pertains to advances in real-time methods in nuclear magnetic resonance, magnetic resonance imaging, and non-invasive medical ablation by offering:
• a new real-time processing method for nuclear magnetic resonance (NMR) spectrum acquisition without external resonator(s), which remains stable despite magnetic field fluctuations,
• a new processing method for nuclear magnetic resonance spectrum acquisition, which remains stable despite magnetic field fluctuations and resonator stability,
• a new method of constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region,
• a new dual frequency dynamic nuclear polarization (DNP) generator that polarizes the spin of electrons and acts as an NMR transmitter,
• a new real-time processing method for visualizing, targeting, and guiding surgical and other non-invasive processes, and
• a new method of non-invasive ablation, heat generation, and chemical reaction activation inside the human body to support a fully automatic or semi-automatic surgical procedure without the use of invasive devices, thus providing material reduction in risk to patient safety.-
公开(公告)号：EP3107642A4
公开(公告)日：2017-11-01
申请号：EP15749068
申请日：2015-02-16
CPC分类号： A61M1/369 , A61F2007/0054 , A61F2007/0089 , A61M1/14 , A61M1/16 , A61M1/1698 , A61M1/32 , A61M1/341 , A61M1/36 , A61M1/3607 , A61M1/3621 , A61M1/3687 , A61M5/44 , A61M2202/00 , A61M2202/0208 , A61M2202/0216 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/3633 , A61M2205/366 , A61M2210/12
摘要： According to some embodiments, a system may treat blood outside the body of a patient. The system may include one or more pumps configured to draw blood from a patient into a fluid flow path at a rate, for example, of 5-7 liters per minute. The system may include one or more heat exchangers coupled to the fluid flow path and configured to heat the blood, for example, to a temperature above 42 degrees Celsius and below 43.2 degrees Celsius.
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公开(公告)号：EP2320840A4
公开(公告)日：2012-09-05
申请号：EP09805610
申请日：2009-08-07
申请人： GEN HOSPITAL CORP
CPC分类号： A61B18/0218 , A61B2017/00747 , A61B2018/00005 , A61B2018/00458 , A61B2018/0047 , A61B2018/00577 , A61B2018/00714 , A61B2018/00815 , A61B2018/00821 , A61B2018/0237 , A61B2018/0293 , A61B2018/143 , A61F7/00 , A61F7/0085 , A61F7/10 , A61F2007/0052 , A61F2007/0056 , A61F2007/0063 , A61F2007/0075 , A61F2007/0086 , A61F2007/0087 , A61F2007/0089 , A61F2007/0095 , A61F2007/0096 , A61F2007/0292
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公开(公告)号：EP1610866A2
公开(公告)日：2006-01-04
申请号：EP04709930.4
申请日：2004-02-10
IPC分类号： A61N5/06
CPC分类号： A46B15/0002 , A46B15/0036 , A46B2200/1066 , A61B18/203 , A61B2017/00057 , A61B2017/00084 , A61B2018/00005 , A61B2018/00452 , A61B2090/065 , A61C1/081 , A61C1/088 , A61C17/3481 , A61C19/06 , A61F7/00 , A61F2007/0087 , A61F2007/0089 , A61F2007/0096 , A61F2007/0292 , A61F2007/108 , A61K8/02 , A61K2800/438 , A61K2800/81 , A61N5/0601 , A61N5/0603 , A61N5/0617 , A61N5/062 , A61N5/0624 , A61N2005/005 , A61N2005/0606 , A61N2005/0644 , A61N2005/0652 , A61N2005/0662 , A61Q11/00
摘要： Oral phototherapy applicators are disclosed that are sized and shaped so as to fit at least partially in a user’s mouth with a plurality of bristles of elongate shape coupled to an apparatus body. The applicators can be adapted to brush the user’s teeth and further include at least one radiation emitter to the body to provide phototherapeutic radiation to a portion of the oral cavity other than tissue in contact with the bristles. In one embodiment, the phototherapy emitter irradiates both a region of tissue in contact with the bristles and a portion of the oral cavity that is not in contact with the apparatus. For example, the apparatus can include at least one emitter that irradiates tooth tissue in contact with the bristles and gum tissue surrounding the tooth tissue.
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