摘要:
The invention pertains to advances in real-time methods in nuclear magnetic resonance by offering: • a new real-time processing method for nuclear magnetic resonance (NMR) spectrum acquisition without external resonator(s), which remains stable despite magnetic field fluctuations, • a new processing method for nuclear magnetic resonance spectrum acquisition, which remains stable despite magnetic field fluctuations and resonator stability, • a new method of constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region, • a new dual frequency dynamic nuclear polarization (DNP) generator that polarizes the spin of electrons and acts as an NMR transmitter.
摘要:
An electromagnetic heating device for heating a living body or an object (15), comprising a cavity resonator (11) made of hollow electroconductive material for receiving a living body or an object (15) therein and heating same by a high frequency electromagnetic field produced therein; and at least an electric field concentrator (14a, 14b) disposed in the cavity resonator (11) separately therefrom. Thus, it is possible to concentrate an electric field to a desired location to supply a strong current into a living body or an object (15). Further, since the electric field concentrator (14a, 14b) is electrically out of contact with the cavity resonator (11), a frequency adjusting element (17a, 17b) and an impedance matching element (19) may be easily provided in the vicinity for optimum transmission of high frequency electromagnetic energy thereby eliminating the need for adjusting the frequency of the high frequency electromagnetic energy source. Since an oscillator without the capability to change its frequency can be manufactured at a fraction of the cost for manufacturing a variable frequency oscillator, the cost of the overall heating device can be drastically reduced. By shaping the free end of the electric field concentrator (14a, 14b), it is possible to achieve a desired degree of energy concentration.
摘要:
Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, and a programmable controller configured to provide instructions to the one or more cooling elements in response to information regarding one or more physiological conditions of the vertebrate subject.
摘要:
A heater (seed) and system for subjecting tumors to closely controlled hypothermia or higher temperatures includes a core of ferromagnetic material having a high resistivity or resistivity of a non-conductor enclosed with a bio-compatible non-magnetic conductive sheath and excited by a coil positioned to establish a magnetic field coupled to the seed. The core is dimensioned so as to reduce demagnetizing effects to acceptable levels. The thickness of the conductive sheath is optimized to achieve a heat generating capacity which is considerably greater than that of the bare ferromagnetic material.
摘要:
The invention pertains to advances in real-time methods in nuclear magnetic resonance, magnetic resonance imaging, and non-invasive medical ablation by offering: • a new real-time processing method for nuclear magnetic resonance (NMR) spectrum acquisition without external resonator(s), which remains stable despite magnetic field fluctuations, • a new processing method for nuclear magnetic resonance spectrum acquisition, which remains stable despite magnetic field fluctuations and resonator stability, • a new method of constructing predetermined magnets from appropriate magnetic material that allows for focusing the magnetic field in a target region, • a new dual frequency dynamic nuclear polarization (DNP) generator that polarizes the spin of electrons and acts as an NMR transmitter, • a new real-time processing method for visualizing, targeting, and guiding surgical and other non-invasive processes, and • a new method of non-invasive ablation, heat generation, and chemical reaction activation inside the human body to support a fully automatic or semi-automatic surgical procedure without the use of invasive devices, thus providing material reduction in risk to patient safety.
摘要:
Devices, systems, and methods are disclosed herein for treatment of a disease, disorder, or condition in a vertebrate subject. A device is provided that includes one or more passive cooling elements configured to be applied to one or more tissues of a vertebrate subject to modulate at least one activity of brown adipose tissue of the vertebrate subject, wherein at least a portion of the one or more passive cooling elements is configured to be implantable, and wherein the one or more passive cooling elements includes a first portion configured to be in association with the one or more tissues to be cooled, and a second portion configured to be placed in association with one or more tissues adjacent to an external epidermal tissue of the vertebrate subject.
摘要:
On provoque une lésion thermique destructrice à n'importe quel emplacement dans le cerveau. La tête (S) d'un patient est maintenue à l'intérieur d'un cadre stéréotactique (3). On entre et on analyse dans un ordinateur (87) les informations recueillies après avoir effectué un examen tomographique et un angiogramme ou avoir procédé à l'imagerie à résonance magnétique. On resynthétise ces informations puis on les projette sous forme d'image vidéo sur un écran faisant face au chirurgien. On introduit un petit objet métallique (63) par exemple une bille, dans la tête du patient via un trou percé à travers le crâne du patient. A l'aide des données fluoroscopiques en temps réel superposées sur l'image de synthèse de structures tridimensionnelles, le chirurgien peut contrôler et manipuler ledit objet à travers les tissus tendres du cerveau du patient jusqu'à une position proche de la zone tumorale ou jusque dans cette dernière. On déclenche ensuite le feu d'un faisceau d'énergie sur ledit objet, ce qui entraîne ledit objet thermiquement plus efficace à détruire la zone tumorale du cerveau. On répète cette procédure jusqu'à éradication de toute la tumeur par hyperthermie très localisée. On peut utiliser la procédure précitée afin de soumettre le cerveau ainsi que d'autre parties du corps à une hyperthermie, chimiothérapie, radiothérapie ainsi qu'à d'autres agents ou traitements.