公开(公告)号：EP2990046A1

公开(公告)日：2016-03-02

申请号：EP14788947.1

申请日：2014-04-23

申请人： Cho Dang Pharm. Co., Ltd.

发明人： KIM, Ki Woon ,  YOO, Hye Dong ,  HONG, Soon Sun ,  KIM, Soo Jung ,  LEE, Hyun Seung ,  FANG, Zhenghuan ,  KANG, Su Jin

IPC分类号： A61K36/896 ,  A61P35/02

CPC分类号： A61K31/365 ,  A61K36/57

摘要： The present invention relates to a pharmaceutical composition containing, as an active ingredient, a Liriodendron tulipifera L. bark extract for treating chronic myelogneous leukemia. More specifically, the present invention relates to the pharmaceutical composition, containing, as the active ingredient, the Liriodendron tulipifera L. bark extract useful in selectively inhibiting mutant enzyme T315I from a mutation of a BCR-ABL fusion gene that causes chronic myelogenous leukemia, and to a use of epi-Tulipinolide which is an active ingredient of the composition.

摘要翻译： 本发明涉及含有一种药物组合物，如在活性成分，用于治疗慢性白血病myelogneous一个北美鹅掌楸L.树皮提取物。 更具体地，本发明涉及药物组合物，含从BCR-ABL融合基因的突变作为活性成分，所述北美鹅掌楸L.树皮提取物中有用的选择性抑制突变酶T315I做的原因的慢性髓细胞性白血病，和 至使用外延Tulipinolide所有这是对组合物的活性成分。

公开(公告)号：EP2624702B1

公开(公告)日：2016-03-02

申请号：EP11831602.5

申请日：2011-10-06

申请人： The Board of Trustees of The University of Arkansas

发明人： QUAVE, Cassandra L. ,  SMELTZER, Mark S. ,  COMPADRE, Cesar M. ,  HENDRICKSON, Howard

IPC分类号： A01N43/90 ,  A01N65/00 ,  A01N65/34 ,  A01P1/00 ,  A61K38/14 ,  A61K38/15 ,  A61K36/75 ,  A61K36/76 ,  A61K36/77 ,  A61K36/87 ,  A61K36/88

CPC分类号： A01N43/90 ,  A01N65/00 ,  A01N65/34 ,  A61K31/19 ,  A61K31/192 ,  A61K31/352 ,  A61K31/366 ,  A61K31/43 ,  A61K31/431 ,  A61K31/496 ,  A61K31/65 ,  A61K31/7048 ,  A61K31/7056 ,  A61K36/185 ,  A61K36/21 ,  A61K36/23 ,  A61K36/24 ,  A61K36/28 ,  A61K36/40 ,  A61K36/45 ,  A61K36/48 ,  A61K36/49 ,  A61K36/51 ,  A61K36/52 ,  A61K36/53 ,  A61K36/57 ,  A61K36/61 ,  A61K36/73 ,  A61K36/75 ,  A61K36/76 ,  A61K36/77 ,  A61K36/87 ,  A61K36/88 ,  A61K36/896 ,  A61K38/12 ,  A61K38/14 ,  A61K38/15 ,  Y02A50/478 ,  A61K2300/00

摘要： The present invention provides polyphenolic compositions derived from a plant that inhibit the formation of a biofilm. Also provided are combinations that comprise at least one phenolic phytochemical and at least one antimicrobial agent that inhibit the growth of an established biofilm. Further, the present invention provides methods for inhibiting the formation and growth of biofilms.

公开(公告)号：EP2815759A1

公开(公告)日：2014-12-24

申请号：EP13749767.3

申请日：2013-02-01

申请人： Cho Dang Pharm. Co., Ltd.

发明人： KIM, Nak Doo

IPC分类号： A61K36/896 ,  A61P1/04 ,  A61P1/00

CPC分类号： A61K31/365 ,  A61K36/57 ,  A61K2236/00

摘要： The present invention relates to a pharmaceutical composition containing, as active ingredients, epitulipinolide and costunolide extracted from the bark of Liriodendron tulipifera. More specifically, the present invention relates to a pharmaceutical composition for treating the gastrointestinal tract, the composition containing, as active ingredients, epitulipinolide and costunolide, which are the active ingredients of the extract from the bark of Liriodendron tulipifera, and to the use thereof as a therapeutic agent for gastrointestinal diseases.

摘要翻译： 本发明涉及含有一种药物组合物，作为活性成分，并从北美鹅掌楸树皮中提取表美鹅掌楸木香。 更具体地，本发明涉及一种药物组合物用于治疗胃肠道，包含该组合物，作为活性成分，表美鹅掌楸和木香，哪些是来自北美鹅掌楸树皮提取物的活性成分，并涉及其作为 用于胃肠道疾病的治疗剂。

公开(公告)号：EP2793812A1

公开(公告)日：2014-10-29

申请号：EP11794375.3

申请日：2011-12-02

申请人： Colgate-Palmolive Company

发明人： FEI, Lin ,  JARACZ, Stanislav ,  YANG, Ying ,  XU, Guofeng

IPC分类号： A61K8/34 ,  A61Q11/00

CPC分类号： A61K8/347 ,  A61K36/57 ,  A61K36/575 ,  A61K2800/49 ,  A61K2800/5922 ,  A61Q11/00

摘要： Oral care compositions comprising isobutyl magnolol and
n -butyl magnolol. A method of enhancing the solubility of isobutyl magnolol in an oral care composition comprises admixing
n -butyl magnolol with an orally acceptable carrier comprising isobutyl magnolol. The composition may be used to treat diseases or conditions of the oral cavity such as caries, gingivitis, periodontitis, tooth yellowing and halitosis.

公开(公告)号：EP2688577A1

公开(公告)日：2014-01-29

申请号：EP12701225.0

申请日：2012-01-24

申请人： Maria Clementine Martin Klosterfrau Vertriebsgesellschaft mbH

发明人： VESTWEBER, Anna-Maria

IPC分类号： A61K36/534 ,  A61K36/57 ,  A61K36/235 ,  A61K36/23 ,  A61P1/02

CPC分类号： A61K36/534 ,  A61K36/23 ,  A61K36/235 ,  A61K36/57

摘要： The invention relates to a composition, in particular a pharmaceutical preparation, preferably for the therapeutic or prophylactic treatment of digestive problems or disturbances, in particular digestive malfunctions, meteorism, flatulence, colic, bloating, stomach pressure, excessive gas formation in the stomach/intestinal tract, or the like, wherein the composition contains - in combination and each in effective amounts, in particular pharmaceutically effective amounts - (a) at least one polysiloxane, (b) peppermint oil, (c) anise oil, (d) fennel oil, and (e) caraway oil.

公开(公告)号：EP2318024A2

公开(公告)日：2011-05-11

申请号：EP09777023.4

申请日：2009-07-08

申请人： Beiersdorf AG

发明人： ESPEL, Anja ,  SCHÄFER, Jessica ,  FEY, Sven ,  BREITENBACH, Ute ,  KNOTT, Anja ,  MUMMERT, Christoper ,  SCHERNER, Cathrin

IPC分类号： A61K36/57 ,  A61K31/728 ,  A61P17/00

CPC分类号： A61Q19/06 ,  A61K8/735 ,  A61K8/97 ,  A61K31/728 ,  A61K36/57 ,  A61Q19/005 ,  A61Q19/007 ,  A61K2300/00

摘要： The invention relates to active substance combinations consisting of an effective amount of anis fruit extract and hyaluronic acid.

公开(公告)号：EP0491913A1

公开(公告)日：1992-07-01

申请号：EP91912841.0

申请日：1991-06-11

申请人： Cedars-Sinai Medical Center

发明人： HO, David, Da-i ,  LI, Xiling, Shirley

IPC分类号： A61K36 ,  A61K35 ,  A61P37 ,  C12Q1 ,  G01N33

CPC分类号： A61K36/355 ,  A61K36/236 ,  A61K36/28 ,  A61K36/315 ,  A61K36/39 ,  A61K36/537 ,  A61K36/539 ,  A61K36/57 ,  A61K36/68 ,  A61K36/718 ,  A61K2300/00

摘要： L'invention met en oeuvre des extraits d'herbes tirés de dix remèdes galéniques chinois (10) présentant une activité significative anti-VIH in vitro et ex vivo, ainsi que leur emploi dans le diagnostic et le traitement du VIH et de maladies apparentéesau VIH.

公开(公告)号：EP2114387B1

公开(公告)日：2016-04-06

申请号：EP08761756.9

申请日：2008-01-11

申请人： Europe Finances

发明人： BERNARD, Philippe ,  RASE, Didier

IPC分类号： A61K31/05 ,  A61K8/34 ,  A61K36/575

CPC分类号： A61K31/05 ,  A61K8/347 ,  A61K8/97 ,  A61K36/54 ,  A61K36/57 ,  A61K36/575 ,  A61K36/899 ,  A61K2800/782 ,  A61Q7/00 ,  A61Q19/08

公开(公告)号：EP2605831B1

公开(公告)日：2014-06-18

申请号：EP11773679.3

申请日：2011-10-11

申请人： Maria Clementine Martin Klosterfrau Vertriebsgesellschaft mbH

发明人： NAUERT, Christian ,  GREVE, Harald

IPC分类号： A61P31/00 ,  A61P11/10 ,  A61P11/12 ,  A61K36/185 ,  A61K36/28 ,  A61K36/25 ,  A61K36/11 ,  A61K36/53 ,  A61K36/235 ,  A61K36/35 ,  A61K36/57

CPC分类号： A61K36/53 ,  A61K36/11 ,  A61K36/185 ,  A61K36/235 ,  A61K36/25 ,  A61K36/28 ,  A61K36/35 ,  A61K36/57

公开(公告)号：EP2496096A4

公开(公告)日：2013-01-23

申请号：EP10829033

申请日：2010-11-03

申请人： ARIZONA HEALTH CONSULTING LLC

发明人： WANG YIBING ,  REILLY PETER J

IPC分类号： A23L1/015 ,  A61K36/57 ,  A61P3/04

CPC分类号： A61K36/57

摘要： Magnoliidae compounds are made by obtaining parts of Magnoliidae plants. The parts of the Magnoliidae plants are mixed with alcohol and water. The mixture of the parts of the Magnoliidae plants, alcohol and water is heated and the parts of the Magnoliidae plants are removed so that a liquid mixture remains. The liquid mixture is drying to form a solid composition. Alcohol and water are added to the solid composition to reconstitute the solid composition into a liquid composition. The liquid composition is heated to form solid matter. The solid matter is dried to obtain a purified composition of the Magnoliidae compounds. A dose of Magnoliidae compounds promotes weight loss and can be administered in liquid form, sublingually, intravenously, in a pharmaceutically acceptable carrier, in combination with a metabolite detoxification agent, in combination with a nutritional or dietary supplement, or in chewing gum.