Filtration membrane
    10.
    发明公开
    Filtration membrane 审中-公开
    Filtrationsmembrane

    公开(公告)号:EP1710011A1

    公开(公告)日:2006-10-11

    申请号:EP05102721.7

    申请日:2005-04-07

    Abstract: The invention is directed to a filtration membrane that is capable for the retention of endotoxines and cytokine inducing substances (CIS) including bacterial DNA and/or DNA fragments from fluid and/or liquid media. The invention is further directed to a method of manufacturing such filtration membranes in a high quality and in an effective and time saving procedure, and to the use of such membranes for the retention of substances from fluids or liquids. The filtration membrane of the invention consists of a polymer blend comprising at least one hydrophobic polymer containing sulfur in its back bone, at least one hydrophilic, uncharged homo-polymer of polyvinylpyrrolidone and at least one polymer containing cationic charges. The method of manufacturing such a filtration membrane comprises dissolving at least one hydrophobic polymer containing sulfur in its back bone and at least one hydrophilic, uncharged polyvinylpyrrolidone and at least one polymer containing cationic charges in at least one solvent to form a polymer solution, subjecting the formed polymer solution to a diffusion-induced phase separation to prepare a filtration membrane, washing and subsequently drying of the filtration membrane.

    Abstract translation: 本发明涉及能够从流体和/或液体介质中保留包含细菌DNA和/或DNA片段的内毒素和细胞因子诱导物质(CIS)的过滤膜。 本发明进一步涉及以高质量和有效且节省时间的方法制造这种过滤膜的方法,以及使用这种膜来保持来自流体或液体的物质。 本发明的过滤膜由包含至少一种在其后骨中含有硫的疏水性聚合物,至少一种亲水的,不带电的聚乙烯吡咯烷酮的聚合物和至少一种含有阳离子电荷的聚合物组成的聚合物共混物构成。 制造这种过滤膜的方法包括将至少一种含有硫的疏水性聚合物溶解在其背骨中,以及至少一种亲水的,不带电的聚乙烯吡咯烷酮和至少一种含至少一种溶剂中的阳离子电荷的聚合物形成聚合物溶液, 形成的聚合物溶液进行扩散诱导的相分离以制备过滤膜,洗涤并随后干燥过滤膜。

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