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公开(公告)号：EP4389280A3
公开(公告)日：2024-10-09
申请号：EP23188005.5
申请日：2023-07-27
发明人： NARASIMHAN, Vinayak , NAMKOONG, Kak , SIDDIQUE, Radwanul Hasan , JUNG, Wonjong , YOON, Youngzoon
CPC分类号： B01L2300/082920130101 , B01L3/502707 , B01L3/50851 , B01L2200/1220130101 , B01L2300/081920130101 , B01L2300/089620130101 , B01L2300/16820130101 , B01L2300/186120130101 , C23C14/5806 , C23C14/06 , C23C14/34 , G01N1/44 , G01N21/0332 , F24S70/25
摘要： An assay repository device for photothermal or joule heating includes an assay container having an interior surface and being configured to house an assay solution, and a nanostructure layer conformally integrated onto the assay container and directly contacting the interior surface, the nanostructure layer being plasmonic and thermally conductive, and including a plurality of nanofeatures having non-uniform sizes and/or non-uniform shapes.
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公开(公告)号：EP3679354B1
公开(公告)日：2024-07-24
申请号：EP18854207.0
申请日：2018-09-07
IPC分类号： G01N21/25 , G01N21/552 , G01N21/78 , G01N33/543 , B01L3/00 , G01N21/64 , G01N21/65 , B82Y30/00
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公开(公告)号：EP4420783A1
公开(公告)日：2024-08-28
申请号：EP23188931.2
申请日：2023-08-01
发明人： Lee, Jae Hong , Park, Jungwon , Kang, Min-Ho , Lee, Minyoung , Jang, Hyeong Seok , Jung, Won Jong , Kim, Jin Ha , Namkoong, Kak , Youn, Hyung Jun
CPC分类号： B01L3/502707 , B01L2200/1220130101 , B01L2300/063620130101 , B01L2300/081920130101 , B01L2300/089320130101 , B01L2300/089620130101 , B01L2300/16120130101 , B01L2400/040620130101 , B81C1/00015 , G01N23/00 , G01N21/6458
摘要： The present disclosure provides methods and apparatuses for biomaterial detection sensors. In some embodiments, a biomaterial detection sensor includes a membrane including a plurality of wells. Each of the plurality of wells is configured to encapsulate a biomaterial contained in a sample solution. A surface of the membrane is selectively modified into at least one of a hydrophilic surface and a hydrophobic surface. In some embodiments, a method of manufacturing a biomaterial detection sensor includes depositing a first membrane and a second membrane on respective surfaces of a wafer, forming a window by etching the first membrane and the first surface of the wafer, forming a plurality of wells on the second membrane, modifying a surface of the second membrane into at least one of a hydrophilic surface and a hydrophobic surface; and transferring a two-dimensional graphene oxide material onto a bottom of each of the plurality of wells.
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公开(公告)号：EP4303317A3
公开(公告)日：2024-04-24
申请号：EP23206492.3
申请日：2018-10-22
IPC分类号： B01L3/00 , C12Q1/6869
CPC分类号： C12Q1/6869 , B01L2300/089620130101
摘要： Techniques for replacing nanopores within a nanopore based sequencing chip are provided. A first electrolyte solution is added to the external reservoir of the sequencing chip, introducing an osmotic imbalance between the reservoir and the well chamber located on the opposite side of a lipid bilayer membrane. The osmotic imbalance causes the membrane to change shape, and a nanopore within the membrane to be ejected. A second electrolyte solution is then added to the external reservoir to provide replacement nanopores and to restore the membrane shape. The replacement nanopores can be inserted into the membrane, effectively replacing the initial pore without causing the destruction of the membrane.
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公开(公告)号：EP4426489A2
公开(公告)日：2024-09-11
申请号：EP22822738.5
申请日：2022-11-03
申请人： Abbott Laboratories
CPC分类号： B01L3/502761 , B01L3/502738 , B01L2200/067320130101 , B01L2200/066820130101 , B01L2300/089620130101 , B01L2300/08720130101 , B01L2300/12320130101 , B01L2300/16120130101 , B01L2300/089320130101 , B01L2400/06520130101 , B01L2400/04320130101 , B01L3/502715 , B01L3/502746 , B01L2200/062120130101 , B01L2200/068920130101 , B01L2200/1020130101 , B01L2300/081620130101 , B01L2300/082920130101 , G01N33/54326 , G01N35/0098 , G01N33/54366 , B03C1/01 , B03C1/288 , B03C1/30 , B03C2201/1820130101 , B03C2201/2620130101 , B03C2201/2220130101
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公开(公告)号：EP4027127B1
公开(公告)日：2024-07-31
申请号：EP22159522.6
申请日：2016-04-08
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公开(公告)号：EP4389280A2
公开(公告)日：2024-06-26
申请号：EP23188005.5
申请日：2023-07-27
发明人： NARASIMHAN, Vinayak , NAMKOONG, Kak , SIDDIQUE, Radwanul Hasan , JUNG, Wonjong , YOON, Youngzoon
CPC分类号： B01L2300/082920130101 , B01L3/502707 , B01L3/50851 , B01L2200/1220130101 , B01L2300/081920130101 , B01L2300/089620130101 , B01L2300/16820130101 , B01L2300/186120130101 , C23C14/5806 , C23C14/06 , C23C14/34 , G01N1/44 , G01N21/0332 , H05B6/36 , F24S70/25
摘要： An assay repository device for photothermal or joule heating includes an assay container having an interior surface and being configured to house an assay solution, and a nanostructure layer conformally integrated onto the assay container and directly contacting the interior surface, the nanostructure layer being plasmonic and thermally conductive, and including a plurality of nanofeatures having non-uniform sizes and/or non-uniform shapes.
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公开(公告)号：EP4427841A2
公开(公告)日：2024-09-11
申请号：EP24190029.9
申请日：2018-09-07
发明人： Quan, Qimin , Liang, Feng
IPC分类号： B01L3/00
CPC分类号： G01N21/253 , G01N21/554 , B01L3/5085 , B01L2200/02620130101 , B01L2200/064720130101 , B01L2200/14120130101 , B01L2300/04420130101 , B01L2300/063620130101 , B01L2300/082920130101 , B01L2300/089320130101 , B01L2300/089620130101 , G01N33/54366 , G01N21/658 , G01N21/648 , G01N21/78 , B82Y30/00
摘要： The present invention generally relates, in some aspects, to articles and methods relating to nanosensors for determination of molecules and other features, e.g., via surface plasmonic resonance, electric resonance, magnetic resonance, color changes, or the like. These articles and methods may be used, for example, for sample detection. The articles described in some aspects of the invention include a microwell array and a nanosensor array. In some embodiments, the nanosensor arrays may utilize nanoparticles positioned on nanostructures that are able to interact with a sample suspected of containing an analyte, such as a single cell. The interaction between nanoparticles and a sample can be detected by a change in applied energy, such as altered electromagnetic radiation caused by surface plasmonic resonance of incident visible light, and/or other types of resonance. Electromagnetic radiation may be applied to a microwell array and nanosensor, and the applied electromagnetic radiation may be altered as a nanosensor interacts with a sample suspected of containing an analyte. In addition, in some embodiments, the nanosensor arrays may utilize nanostructures and the binding of analytes may be determined based on optical or color changes.
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公开(公告)号：EP3990185B1
公开(公告)日：2024-09-11
申请号：EP20823708.1
申请日：2020-05-19
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公开(公告)号：EP3519894B1
公开(公告)日：2024-04-17
申请号：EP17857180.8
申请日：2017-09-11
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