DIFFRACTION GRATING-BASED ENCODED MICRO-PARTICLES FOR MULTIPLEXED EXPERIMENTS
    8.
    发明公开
    DIFFRACTION GRATING-BASED ENCODED MICRO-PARTICLES FOR MULTIPLEXED EXPERIMENTS 审中-公开
    上形成衍射点阵存储器微粒的进行实验复用的基础

    公开(公告)号:EP1535242A1

    公开(公告)日:2005-06-01

    申请号:EP03793272.0

    申请日:2003-08-20

    IPC分类号: G06T5/00

    摘要: Microparticles (8) includes an optical substrate (10) having at least one diffraction grating (12) disposed therein. The grating (12) having a plurality of colocated pitches Λ which represent a unique identification digital code that is detected when illuminated by incident light (24). The incident light (24) may be directed transversely from the side of the substrate (10) with a narrow band (single wavelength) or multiple wavelength source, in which case the code is represented by a spatial distribution of light or a wavelength spectrum, respectively. The code may be digital binary or may be other numerical bases. The micro-particles (8) can provide a large number of unique codes, e.g., greater than 67 million codes, and can withstand harsh environments. The micro­particles (8) are functionalized by coating them with a material/substance of interest, which are then used to perform multiplexed experiments involving chemical processes, e.g., DNA testing and combinatorial chemistry.