公开(公告)号：EP0836651A4

公开(公告)日：2004-07-14

申请号：EP96923255

申请日：1996-06-07

申请人： IGEN INT INC

发明人： MARTIN MARK T ,  LIANG PAM ,  DONG LIWEN

IPC分类号： C07D499/26 ,  C12Q1/34 ,  G01N21/78 ,  G01N27/327 ,  G01N27/42 ,  C12Q1/00 ,  A61K51/00 ,  C07D327/10 ,  C12Q1/04 ,  C12Q1/06 ,  G01N31/00 ,  G01N33/53

CPC分类号： C12Q1/34 ,  G01N2333/986 ,  G01N2415/00 ,  G01N2458/30 ,  G01N2458/40

摘要： The present invention provides detectable compounds comprising a chemically-transformable first compound covalently linked to an electrochemiluminescent compound. These compounds are useful in processes and kits that monitor the status of the first compound and derive information from the monitoring. The figure shows a proposed ECL mechanism depicting reaction steps associated with the use of TPA as a nonconjugated reductant.